Raul Perez-Jimenez
Raul Perez-Jimenez
Professor at CIC bioGUNE
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Stretching single talin rod molecules activates vinculin binding
A Del Rio, R Perez-Jimenez, R Liu, P Roca-Cusachs, JM Fernandez, ...
Science 323 (5914), 638-641, 2009
Probing the chemistry of thioredoxin catalysis with force
AP Wiita, R Perez-Jimenez, KA Walther, F Gräter, BJ Berne, A Holmgren, ...
Nature 450 (7166), 124-127, 2007
Single-molecule paleoenzymology probes the chemistry of resurrected enzymes
R Perez-Jimenez, A Inglés-Prieto, ZM Zhao, I Sanchez-Romero, ...
Nature structural & molecular biology 18 (5), 592-596, 2011
The efficiency of different salts to screen charge interactions in proteins: a Hofmeister effect?
R Perez-Jimenez, R Godoy-Ruiz, B Ibarra-Molero, JM Sanchez-Ruiz
Biophysical journal 86 (4), 2414-2429, 2004
Conservation of protein structure over four billion years
A Ingles-Prieto, B Ibarra-Molero, A Delgado-Delgado, R Perez-Jimenez, ...
Structure 21 (9), 1690-1697, 2013
Diversity of chemical mechanisms in thioredoxin catalysis revealed by single-molecule force spectroscopy
R Perez-Jimenez, J Li, P Kosuri, I Sanchez-Romero, AP Wiita, ...
Nature structural & molecular biology 16 (8), 890-896, 2009
Mechanical unfolding pathways of the enhanced yellow fluorescent protein revealed by single molecule force spectroscopy
R Perez-Jimenez, S Garcia-Manyes, SRK Ainavarapu, JM Fernandez
Journal of Biological Chemistry 281 (52), 40010-40014, 2006
Robustness of downhill folding: guidelines for the analysis of equilibrium folding experiments on small proteins
AN Naganathan, R Perez-Jimenez, JM Sanchez-Ruiz, V Munoz
Biochemistry 44 (20), 7435-7449, 2005
Single-molecule force spectroscopy approach to enzyme catalysis
J Alegre-Cebollada, R Perez-Jimenez, P Kosuri, JM Fernandez
Journal of Biological Chemistry 285 (25), 18961-18966, 2010
Natural selection for kinetic stability is a likely origin of correlations between mutational effects on protein energetics and frequencies of amino acid occurrences in …
R Godoy-Ruiz, F Ariza, D Rodriguez-Larrea, R Perez-Jimenez, ...
Journal of molecular biology 362 (5), 966-978, 2006
Large-scale modulation of thermodynamic protein folding barriers linked to electrostatics
Ø Halskau Jr, R Perez-Jimenez, B Ibarra-Molero, J Underhaug, V Muñoz, ...
Proceedings of the National Academy of Sciences 105 (25), 8625-8630, 2008
Relation between protein stability, evolution and structure, as probed by carboxylic acid mutations
R Godoy-Ruiz, R Perez-Jimenez, B Ibarra-Molero, JM Sanchez-Ruiz
Journal of molecular biology 336 (2), 313-318, 2004
A simple two-state protein unfolds mechanically via multiple heterogeneous pathways at single-molecule resolution
J Schönfelder, R Perez-Jimenez, V Muñoz
Nature communications 7 (1), 11777, 2016
Mechanical architecture and folding of E. coli type 1 pilus domains
A Alonso-Caballero, J Schönfelder, S Poly, F Corsetti, D De Sancho, ...
Nature communications 9 (1), 2758, 2018
Protein folding under mechanical forces: a physiological view
Y Javadi, JM Fernandez, R Perez-Jimenez
Physiology, 2013
Dwell time analysis of a single-molecule mechanochemical reaction
R Szoszkiewicz, SRK Ainavarapu, AP Wiita, R Perez-Jimenez, ...
Langmuir 24 (4), 1356-1364, 2008
Navigating the downhill protein folding regime via structural homologues
AN Naganathan, P Li, R Perez-Jimenez, JM Sanchez-Ruiz, V Munoz
Journal of the American Chemical Society 132 (32), 11183-11190, 2010
A designed protein as experimental model of primordial folding
M Sadqi, E de Alba, R Pérez-Jiménez, JM Sanchez-Ruiz, V Muñoz
Proceedings of the National Academy of Sciences 106 (11), 4127-4132, 2009
A stability pattern of protein hydrophobic mutations that reflects evolutionary structural optimization
R Godoy-Ruiz, R Perez-Jimenez, B Ibarra-Molero, JM Sanchez-Ruiz
Biophysical journal 89 (5), 3320-3331, 2005
The influence of disulfide bonds on the mechanical stability of proteins is context dependent
A Manteca, Á Alonso-Caballero, M Fertin, S Poly, D De Sancho, ...
Journal of Biological Chemistry 292 (32), 13374-13380, 2017
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