| The NAD+ precursor nicotinamide riboside rescues mitochondrial defects and neuronal loss in iPSC and fly models of Parkinson’s disease DC Schöndorf, D Ivanyuk, P Baden, A Sanchez-Martinez, S De Cicco, ... Cell reports 23 (10), 2976-2988, 2018 | 300 | 2018 |
| Dynamic control of proinflammatory cytokines Il-1β and Tnf-α by macrophages in zebrafish spinal cord regeneration TM Tsarouchas, D Wehner, L Cavone, T Munir, M Keatinge, M Lambertus, ... Nature communications 9 (1), 4670, 2018 | 213 | 2018 |
| Glucocerebrosidase 1 deficient Danio rerio mirror key pathological aspects of human Gaucher disease and provide evidence of early microglial activation … M Keatinge, H Bui, A Menke, YC Chen, AM Sokol, Q Bai, F Ellett, ... Human molecular genetics 24 (23), 6640-6652, 2015 | 132 | 2015 |
| TigarB causes mitochondrial dysfunction and neuronal loss in PINK1 deficiency LJ Flinn, M Keatinge, S Bretaud, H Mortiboys, H Matsui, E De Felice, ... Annals of neurology 74 (6), 837-847, 2013 | 95 | 2013 |
| Rapid clearance of cellular debris by microglia limits secondary neuronal cell death after brain injury in vivo C Herzog, L Pons Garcia, M Keatinge, D Greenald, C Moritz, F Peri, ... Development 146 (9), dev174698, 2019 | 89 | 2019 |
| Inhibition of the mitochondrial calcium uniporter rescues dopaminergic neurons in pink1−/− zebrafish S Soman, M Keatinge, M Moein, M Da Costa, H Mortiboys, A Skupin, ... European Journal of Neuroscience 45 (4), 528-535, 2017 | 88 | 2017 |
| Restriction of mitochondrial calcium overload by mcu inactivation renders a neuroprotective effect in zebrafish models of Parkinson's disease SK Soman, M Bazała, M Keatinge, O Bandmann, J Kuznicki Biology open 8 (10), bio044347, 2019 | 59 | 2019 |
| A unique macrophage subpopulation signals directly to progenitor cells to promote regenerative neurogenesis in the zebrafish spinal cord L Cavone, T McCann, LK Drake, EA Aguzzi, AM Oprişoreanu, E Pedersen, ... Developmental cell 56 (11), 1617-1630. e6, 2021 | 45 | 2021 |
| CRISPR gRNA phenotypic screening in zebrafish reveals pro-regenerative genes in spinal cord injury M Keatinge, TM Tsarouchas, T Munir, NJ Porter, J Larraz, D Gianni, ... PLoS genetics 17 (4), e1009515, 2021 | 45 | 2021 |
| Lysosomal and phagocytic activity is increased in astrocytes during disease progression in the SOD1 G93A mouse model of amyotrophic lateral sclerosis DJ Baker, DJ Blackburn, M Keatinge, D Sokhi, P Viskaitis, PR Heath, ... Frontiers in Cellular Neuroscience 9, 410, 2015 | 44 | 2015 |
| PINK1 deficiency impairs adult neurogenesis of dopaminergic neurons SJ Brown, I Boussaad, J Jarazo, JC Fitzgerald, P Antony, M Keatinge, ... Scientific reports 11 (1), 6617, 2021 | 28 | 2021 |
| Brain tumours repurpose endogenous neuron to microglia signalling mechanisms to promote their own proliferation K Chia, M Keatinge, J Mazzolini, D Sieger Elife 8, e46912, 2019 | 23 | 2019 |
| Ablation of the pro-inflammatory master regulator miR-155 does not mitigate neuroinflammation or neurodegeneration in a vertebrate model of Gaucher's disease L Watson, M Keatinge, M Gegg, Q Bai, MC Sandulescu, A Vardi, ... Neurobiology of Disease 127, 563-569, 2019 | 21 | 2019 |
| GCH1 deficiency activates brain innate immune response and impairs tyrosine hydroxylase homeostasis H Larbalestier, M Keatinge, L Watson, E White, S Gowda, W Wei, K Koler, ... Journal of Neuroscience 42 (4), 702-716, 2022 | 14 | 2022 |
| The NAD+ precursor nicotinamide riboside rescues mitochondrial defects and neuronal loss in iPSC and fly models of Parkinson’s disease. Cell Rep 23: 2976–2988 DC Schöndorf, D Ivanyuk, P Baden, A Sanchez-Martinez, S De Cicco, ... | 11 | 2018 |
| The NAD+ precursor nicotinamide riboside rescues mitochondrial defects and neuronal loss in iPSC and Fly models of Parkinson’s disease. Cell Rep 23 (10): 2976–2988 DC Schondorf, D Ivanyuk, P Baden, A Sanchez-Martinez, S De Cicco, ... | 7 | 2018 |
| RNA-seq analysis and compound screening highlight multiple signalling pathways regulating secondary cell death after acute CNS injury in vivo C Herzog, D Greenald, J Larraz, M Keatinge, L Herrgen Biology Open 9 (5), bio050260, 2020 | 5 | 2020 |
| Ankk1 Loss of Function Disrupts Dopaminergic Pathways in Zebrafish A Leggieri, J García-González, JV Torres-Perez, W Havelange, ... Frontiers in Neuroscience 16, 794653, 2022 | 3 | 2022 |
| Dynamic control of proinflammatory cytokines Il-1β and Tnf-α by macrophages is necessary for functional spinal cord regeneration in zebrafish TM Tsarouchas, D Wehner, L Cavone, T Munir, M Keatinge, M Lambertus, ... bioRxiv, 332197, 2018 | 2 | 2018 |
| Unexpected phenotypic and molecular changes of combined glucocerebrosidase and acid sphingomyelinase deficiency M Keatinge, ME Gegg, L Watson, H Mortiboys, N Li, M Dunning, D Ailani, ... Disease Models & Mechanisms 16 (6), dmm049954, 2023 | 1 | 2023 |
