| A platform of synthetic lethal gene interaction networks reveals that the GNAQ uveal melanoma oncogene controls the hippo pathway through FAK X Feng, N Arang, DC Rigiracciolo, JS Lee, H Yeerna, Z Wang, S Lubrano, ... Cancer cell 35 (3), 457-472. e5, 2019 | 212 | 2019 |
| Copper activates HIF-1α/GPER/VEGF signalling in cancer cells DC Rigiracciolo, A Scarpelli, R Lappano, A Pisano, MF Santolla, ... Oncotarget 6 (33), 34158, 2015 | 146 | 2015 |
| The lauric acid-activated signaling prompts apoptosis in cancer cells R Lappano, A Sebastiani, F Cirillo, DC Rigiracciolo, GR Galli, R Curcio, ... Cell death discovery 3 (1), 1-9, 2017 | 136 | 2017 |
| SIRT1 is involved in oncogenic signaling mediated by GPER in breast cancer MF Santolla, S Avino, M Pellegrino, EM De Francesco, P De Marco, ... Cell death & disease 6 (7), e1834-e1834, 2015 | 87 | 2015 |
| Focal adhesion kinase (FAK) activation by estrogens involves GPER in triple-negative breast cancer cells DC Rigiracciolo, MF Santolla, R Lappano, A Vivacqua, F Cirillo, GR Galli, ... Journal of Experimental & Clinical Cancer Research 38, 1-16, 2019 | 78 | 2019 |
| IGF-1/IGF-1R/FAK/YAP transduction signaling prompts growth effects in triple-negative breast cancer (TNBC) cells DC Rigiracciolo, N Nohata, R Lappano, F Cirillo, M Talia, D Scordamaglia, ... Cells 9 (4), 1010, 2020 | 76* | 2020 |
| GPER is involved in the stimulatory effects of aldosterone in breast cancer cells and breast tumor-derived endothelial cells DC Rigiracciolo, A Scarpelli, R Lappano, A Pisano, MF Santolla, S Avino, ... Oncotarget 7 (1), 94, 2016 | 71 | 2016 |
| Pregnancy augments G protein estrogen receptor (GPER) induced vasodilation in rat uterine arteries via the nitric oxide-cGMP signaling pathway T Tropea, EM De Francesco, D Rigiracciolo, M Maggiolini, M Wareing, ... PLoS One 10 (11), e0141997, 2015 | 68 | 2015 |
| GPER, IGF‐IR, and EGFR transduction signaling are involved in stimulatory effects of zinc in breast cancer cells and cancer‐associated fibroblasts A Pisano, MF Santolla, EM De Francesco, P De Marco, DC Rigiracciolo, ... Molecular carcinogenesis 56 (2), 580-593, 2017 | 67 | 2017 |
| GPER mediates a feedforward FGF2/FGFR1 paracrine activation coupling CAFs to cancer cells toward breast tumor progression MF Santolla, A Vivacqua, R Lappano, DC Rigiracciolo, F Cirillo, GR Galli, ... Cells 8 (3), 223, 2019 | 58 | 2019 |
| The IL1β-IL1R signaling is involved in the stimulatory effects triggered by hypoxia in breast cancer cells and cancer-associated fibroblasts (CAFs) R Lappano, M Talia, F Cirillo, DC Rigiracciolo, D Scordamaglia, R Guzzi, ... Journal of Experimental & Clinical Cancer Research 39, 1-22, 2020 | 56 | 2020 |
| Cancer associated fibroblasts: role in breast cancer and potential as therapeutic targets R Lappano, DC Rigiracciolo, A Belfiore, M Maggiolini, EM De Francesco Expert opinion on therapeutic targets 24 (6), 559-572, 2020 | 53 | 2020 |
| miR-221 stimulates breast cancer cells and cancer-associated fibroblasts (CAFs) through selective interference with the A20/c-Rel/CTGF signaling MF Santolla, R Lappano, F Cirillo, DC Rigiracciolo, A Sebastiani, ... Journal of Experimental & Clinical Cancer Research 37, 1-12, 2018 | 52 | 2018 |
| Protective role of GPER agonist G‐1 on cardiotoxicity induced by doxorubicin EM De Francesco, C Rocca, F Scavello, D Amelio, T Pasqua, ... Journal of Cellular Physiology 232 (7), 1640-1649, 2017 | 51 | 2017 |
| Notch1 mediates preconditioning protection induced by GPER in normotensive and hypertensive female rat hearts C Rocca, S Femminò, G Aquila, MC Granieri, EM De Francesco, ... Frontiers in physiology 9, 368307, 2018 | 39 | 2018 |
| Stimulatory actions of IGF-I are mediated by IGF-IR cross-talk with GPER and DDR1 in mesothelioma and lung cancer cells S Avino, P De Marco, F Cirillo, MF Santolla, EM De Francesco, MG Perri, ... Oncotarget 7 (33), 52710, 2016 | 37 | 2016 |
| Focal adhesion kinase fine tunes multifaced signals toward breast cancer progression DC Rigiracciolo, F Cirillo, M Talia, L Muglia, JS Gutkind, M Maggiolini, ... Cancers 13 (4), 645, 2021 | 35 | 2021 |
| The G protein-coupled estrogen receptor (GPER) expression correlates with pro-metastatic pathways in ER-negative breast cancer: a bioinformatics analysis M Talia, EM De Francesco, DC Rigiracciolo, MG Muoio, L Muglia, ... Cells 9 (3), 622, 2020 | 34 | 2020 |
| Recent advances on the role of G protein-coupled receptors in hypoxia-mediated signaling R Lappano, D Rigiracciolo, P De Marco, S Avino, AR Cappello, C Rosano, ... The AAPS journal 18, 305-310, 2016 | 29 | 2016 |
| miR-338-3p is regulated by estrogens through GPER in breast cancer cells and cancer-associated fibroblasts (CAFs) A Vivacqua, A Sebastiani, AM Miglietta, DC Rigiracciolo, F Cirillo, ... Cells 7 (11), 203, 2018 | 28 | 2018 |
J. Silvio Gutkind, Ph.D.UCSD, Distinguished Professor and Chair, Dept. Pharmacology, AD Basic Science Moores Cancer CenterDirección de correo verificada de ucsd.edu
