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Clemens Schmitt
Clemens Schmitt
Universitätsprofessor und Vorstand Universitätsklinik für Hämatologie und Internistische Onkologie, Kepler Universitätsklinikum, Johannes Kepler Universität, Linz
Dirección de correo verificada de kepleruniklinikum.at
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Cellular senescence: defining a path forward
V Gorgoulis, PD Adams, A Alimonti, DC Bennett, O Bischof, C Bishop, ...
Cell 179 (4), 813-827, 2019
17972019
Oncogene-induced senescence as an initial barrier in lymphoma development
M Braig, S Lee, C Loddenkemper, C Rudolph, AHFM Peters, ...
Nature 436 (7051), 660-665, 2005
14622005
A senescence program controlled by p53 and p16INK4a contributes to the outcome of cancer therapy
CA Schmitt, JS Fridman, M Yang, S Lee, E Baranov, RM Hoffman, ...
Cell 109 (3), 335-346, 2002
12382002
Senescence-associated reprogramming promotes cancer stemness
M Milanovic, DNY Fan, D Belenki, JHM Däbritz, Z Zhao, Y Yu, JR Dörr, ...
Nature 553 (7686), 96-100, 2018
8642018
Dissecting p53 tumor suppressor functions in vivo
CA Schmitt, JS Fridman, M Yang, E Baranov, RM Hoffman, SW Lowe
Cancer cell 1 (3), 289-298, 2002
6142002
INK4a/ARF mutations accelerate lymphomagenesis and promote chemoresistance by disabling p53
CA Schmitt, ME McCurrach, E de Stanchina, RR Wallace-Brodeur, ...
Genes & development 13 (20), 2670-2677, 1999
5891999
Synthetic lethal metabolic targeting of cellular senescence in cancer therapy
JR Dörr, Y Yu, M Milanovic, G Beuster, C Zasada, JHM Däbritz, J Lisec, ...
Nature 501 (7467), 421-425, 2013
5662013
Inhibition of RNA polymerase I as a therapeutic strategy to promote cancer-specific activation of p53
MJ Bywater, G Poortinga, E Sanij, N Hein, A Peck, C Cullinane, M Wall, ...
Cancer cell 22 (1), 51-65, 2012
5642012
The dynamic nature of senescence in cancer
S Lee, CA Schmitt
Nature cell biology 21 (1), 94-101, 2019
4822019
Apoptosis and therapy
CA Schmitt, SW Lowe
The Journal of pathology 187 (1), 127-137, 1999
4541999
Senescence, apoptosis and therapy—cutting the lifelines of cancer
CA Schmitt
Nature Reviews Cancer 3 (4), 286-295, 2003
4222003
Oncogene-induced senescence: putting the brakes on tumor development
M Braig, CA Schmitt
Cancer research 66 (6), 2881-2884, 2006
3642006
Genetic analysis of chemoresistance in primary murine lymphomas
CA Schmitt, CT Rosenthal, SW Lowe
Nature medicine 6 (9), 1029-1035, 2000
3422000
Cellular senescence and cancer treatment
CA Schmitt
Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1775 (1), 5-20, 2007
3382007
Tumor stroma-derived TGF-β limits myc-driven lymphomagenesis via Suv39h1-dependent senescence
M Reimann, S Lee, C Loddenkemper, JR Dörr, V Tabor, P Aichele, ...
Cancer cell 17 (3), 262-272, 2010
2112010
Therapy-induced senescence: opportunities to improve anticancer therapy
PG Prasanna, DE Citrin, J Hildesheim, MM Ahmed, S Venkatachalam, ...
JNCI: Journal of the National Cancer Institute 113 (10), 1285-1298, 2021
1822021
Hematopoietic lineage distribution and evolutionary dynamics of clonal hematopoiesis
CM Arends, J Galan-Sousa, K Hoyer, W Chan, M Jäger, K Yoshida, ...
Leukemia 32 (9), 1908-1919, 2018
1662018
Hypoxia-inducible factor 1α determines gastric cancer chemosensitivity via modulation of p53 and NF-κB
N Rohwer, C Dame, A Haugstetter, B Wiedenmann, K Detjen, CA Schmitt, ...
PloS one 5 (8), e12038, 2010
1642010
FoxO transcription factors suppress Myc-driven lymphomagenesis via direct activation of Arf
C Bouchard, S Lee, V Paulus-Hock, C Loddenkemper, M Eilers, ...
Genes & development 21 (21), 2775-2787, 2007
1562007
Targeting the senescence-overriding cooperative activity of structurally unrelated H3K9 demethylases in melanoma
Y Yu, K Schleich, B Yue, S Ji, P Lohneis, K Kemper, MR Silvis, N Qutob, ...
Cancer cell 33 (2), 322-336. e8, 2018
1422018
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Artículos 1–20