The N6-methyladenosine (m6A)-forming enzyme METTL3 controls myeloid differentiation of normal hematopoietic and leukemia cells LP Vu, BF Pickering, Y Cheng, S Zaccara, D Nguyen, G Minuesa, T Chou, ... Nature medicine 23 (11), 1369-1376, 2017 | 1026 | 2017 |
PI3K inhibition results in enhanced estrogen receptor function and dependence in hormone receptor–positive breast cancer A Bosch, Z Li, A Bergamaschi, H Ellis, E Toska, A Prat, JJ Tao, DE Spratt, ... Science translational medicine 7 (283), 283ra51-283ra51, 2015 | 343 | 2015 |
Transport of lamivudine [(-)-β-l-2′, 3′-dideoxy-3′-thiacytidine] and high-affinity interaction of nucleoside reverse transcriptase inhibitors with human organic cation … G Minuesa, C Volk, M Molina-Arcas, V Gorboulev, I Erkizia, P Arndt, ... Journal of pharmacology and experimental therapeutics 329 (1), 252-261, 2009 | 160 | 2009 |
Transformation of the intestinal epithelium by the MSI2 RNA-binding protein S Wang, N Li, M Yousefi, A Nakauka-Ddamba, F Li, K Parada, S Rao, ... Nature communications 6 (1), 6517, 2015 | 140 | 2015 |
Small-molecule targeting of MUSASHI RNA-binding activity in acute myeloid leukemia G Minuesa, SK Albanese, W Xie, Y Kazansky, D Worroll, A Chow, ... Nature communications 10 (1), 2691, 2019 | 116 | 2019 |
Musashi2 sustains the mixed-lineage leukemia–driven stem cell regulatory program SM Park, M Gönen, L Vu, G Minuesa, P Tivnan, TS Barlowe, J Taggart, ... The Journal of clinical investigation 125 (3), 1286-1298, 2015 | 111 | 2015 |
The Msi family of RNA-binding proteins function redundantly as intestinal oncoproteins N Li, M Yousefi, A Nakauka-Ddamba, F Li, L Vandivier, K Parada, ... Cell reports 13 (11), 2440-2455, 2015 | 105 | 2015 |
Drug uptake transporters in antiretroviral therapy G Minuesa, I Huber-Ruano, M Pastor-Anglada, H Koepsell, B Clotet, ... Pharmacology & therapeutics 132 (3), 268-279, 2011 | 102 | 2011 |
Functional screen of MSI2 interactors identifies an essential role for SYNCRIP in myeloid leukemia stem cells LP Vu, C Prieto, EM Amin, S Chhangawala, A Krivtsov, MN Calvo-Vidal, ... Nature genetics 49 (6), 866-875, 2017 | 86 | 2017 |
Peptidomimetic blockade of MYB in acute myeloid leukemia K Ramaswamy, L Forbes, G Minuesa, T Gindin, F Brown, MG Kharas, ... Nature communications 9 (1), 110, 2018 | 84 | 2018 |
Expression and functionality of anti-human immunodeficiency virus and anticancer drug uptake transporters in immune cells G Minuesa, S Purcet, I Erkizia, M Molina-Arcas, M Bofill, ... Journal of Pharmacology and Experimental Therapeutics 324 (2), 558-567, 2008 | 82 | 2008 |
PI3K inhibition activates SGK1 via a feedback loop to promote chromatin-based regulation of ER-dependent gene expression E Toska, P Castel, S Chhangawala, A Arruabarrena-Aristorena, C Chan, ... Cell reports 27 (1), 294-306. e5, 2019 | 57 | 2019 |
A 1536-well fluorescence polarization assay to screen for modulators of the MUSASHI family of RNA-binding proteins G Minuesa, C Antczak, D Shum, C Radu, B Bhinder, Y Li, H Djaballah, ... Combinatorial chemistry & high throughput screening 17 (7), 596-609, 2014 | 43 | 2014 |
Formation of toxic oligomeric assemblies of RNA-binding protein: Musashi in Alzheimer’s disease U Sengupta, M Montalbano, S McAllen, G Minuesa, M Kharas, R Kayed Acta neuropathologica communications 6, 1-14, 2018 | 37 | 2018 |
Convergent organization of aberrant MYB complex controls oncogenic gene expression in acute myeloid leukemia S Takao, L Forbes, M Uni, S Cheng, JMB Pineda, Y Tarumoto, P Cifani, ... Elife 10, e65905, 2021 | 36 | 2021 |
Nucleoside transporters and human organic cation transporter 1 determine the cellular handling of DNA‐methyltransferase inhibitors C Arimany‐Nardi, E Errasti‐Murugarren, G Minuesa, J Martinez‐Picado, ... British journal of pharmacology 171 (16), 3868-3880, 2014 | 32 | 2014 |
Role of human organic cation transporter 1 (hOCT1) polymorphisms in lamivudine (3TC) uptake and drug-drug interactions C Arimany-Nardi, G Minuesa, T Keller, I Erkizia, H Koepsell, ... Frontiers in pharmacology 7, 175, 2016 | 26 | 2016 |
3′-Azido-2′, 3′-dideoxythymidine (zidovudine) uptake mechanisms in T lymphocytes S Purcet, G Minuesa, M Molina-Arcas, I Erkizia, FJ Casado, B Clotet, ... Antiviral therapy 11 (6), 803-812, 2006 | 23 | 2006 |
P-glycoprotein (ABCB1) activity decreases raltegravir disposition in primary CD4+P-gphigh cells and correlates with HIV-1 viral load G Minuesa, C Arimany-Nardi, I Erkizia, S Cedeno, J Moltó, B Clotet, ... Journal of antimicrobial chemotherapy 71 (10), 2782-2792, 2016 | 22 | 2016 |
MoiRNAiFold: a novel tool for complex in silico RNA design G Minuesa, C Alsina, JA Garcia-Martin, JC Oliveros, I Dotu Nucleic acids research 49 (9), 4934-4943, 2021 | 17 | 2021 |