Synaptotoxicity of Alzheimer beta amyloid can be explained by its membrane perforating property FJ Sepulveda, J Parodi, RW Peoples, C Opazo, LG Aguayo PloS one 5 (7), e11820, 2010 | 191 | 2010 |
β-amyloid causes depletion of synaptic vesicles leading to neurotransmission failure J Parodi, FJ Sepulveda, J Roa, C Opazo, NC Inestrosa, LG Aguayo Journal of Biological Chemistry 285 (4), 2506-2514, 2010 | 190 | 2010 |
Canonical Wnt3a modulates intracellular calcium and enhances excitatory neurotransmission in hippocampal neurons ME Avila, FJ Sepúlveda, CF Burgos, G Moraga-Cid, J Parodi, RT Moon, ... Journal of biological chemistry 285 (24), 18939-18947, 2010 | 97 | 2010 |
Differential roles of NMDA receptor subtypes NR2A and NR2B in dendritic branch development and requirement of RasGRF1 FJ Sepulveda, FJ Bustos, E Inostroza, FA Zúñiga, RL Neve, M Montecino, ... Journal of neurophysiology 103 (4), 1758-1770, 2010 | 87 | 2010 |
Biphasic effects of copper on neurotransmission in rat hippocampal neurons C Peters, B Muñoz, FJ Sepúlveda, J Urrutia, M Quiroz, S Luza, ... Journal of Neurochemistry 119 (1), 78-88, 2011 | 74 | 2011 |
Nature of the neurotoxic membrane actions of amyloid-β on hippocampal neurons in Alzheimer's disease FJ Sepúlveda, H Fierro, E Fernandez, C Castillo, RW Peoples, C Opazo, ... Neurobiology of aging 35 (3), 472-481, 2014 | 70 | 2014 |
Nature of the neurotoxic membrane actions of amyloid-β on hippocampal neurons in Alzheimer's disease FJ Sepúlveda, H Fierro, E Fernandez, C Castillo, RW Peoples, C Opazo, ... Neurobiology of aging 35 (3), 472-481, 2014 | 70 | 2014 |
Effect of cholesterol on membrane fluidity and association of Aβ oligomers and subsequent neuronal damage: A Double-Edged Sword EJ Fernández-Pérez, FJ Sepúlveda, C Peters, D Bascuñán, ... Frontiers in aging neuroscience 10, 226, 2018 | 66 | 2018 |
Glial hypothalamic inhibition of GLUT2 expression alters satiety, impacting eating behavior MJ Barahona, P Llanos, A Recabal, K Escobar‐Acuña, R Elizondo‐Vega, ... Glia 66 (3), 592-605, 2018 | 53 | 2018 |
Soluble Aβ 1-40 peptide increases excitatory neurotransmission and induces epileptiform activity in hippocampal neurons ME Cuevas, H Haensgen, FJ Sepúlveda, G Zegers, J Roa, C Opazo, ... Journal of Alzheimer's Disease 23 (4), 673-687, 2011 | 39 | 2011 |
Regulation of glycinergic and GABAergic synaptogenesis by brain-derived neurotrophic factor in developing spinal neurons MA Carrasco, P Castro, FJ Sepulveda, JC Tapia, K Gatica, MI Davis, ... Neuroscience 145 (2), 484-494, 2007 | 39 | 2007 |
Role of membrane GM1 on early neuronal membrane actions of Aβ during onset of Alzheimer's disease EJ Fernández-Pérez, FJ Sepúlveda, R Peoples, LG Aguayo Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1863 (12 …, 2017 | 36 | 2017 |
Adenovirus-mediated suppression of hypothalamic glucokinase affects feeding behavior RM Uranga, C Millán, MJ Barahona, A Recabal, M Salgado, F Martinez, ... Scientific Reports 7 (1), 3697, 2017 | 29 | 2017 |
Alzheimer β-amyloid blocks epileptiform activity in hippocampal neurons FJ Sepúlveda, C Opazo, LG Aguayo Molecular and Cellular Neuroscience 41 (4), 420-428, 2009 | 24 | 2009 |
Ibuprofen inhibits the synaptic failure induced by the amyloid-β peptide in hippocampal neurons MP Zurita, G Munoz, FJ Sepulveda, P Gomez, C Castillo, CF Burgos, ... Journal of Alzheimer's Disease 35 (3), 463-473, 2013 | 19 | 2013 |
Copper-uptake is critical for the down regulation of synapsin and dynamin induced by neocuproine: modulation of synaptic activity in hippocampal neurons PA Castro, A Ramirez, FJ Sepúlveda, C Peters, H Fierro, J Waldron, ... Frontiers in Aging Neuroscience 6, 319, 2014 | 17 | 2014 |
The level of NMDA receptor in the membrane modulates amyloid-β association and perforation C Peters, FJ Sepúlveda, EJ Fernández-Pérez, RW Peoples, LG Aguayo Journal of Alzheimer's Disease 53 (1), 197-207, 2016 | 16 | 2016 |
Anti‐homeostatic synaptic plasticity of glycine receptor function after chronic strychnine in developing cultured mouse spinal neurons MA Carrasco, PA Castro, FJ Sepulveda, M Cuevas, JC Tapia, P Izaurieta, ... Journal of neurochemistry 100 (5), 1143-1154, 2007 | 16 | 2007 |
Sustained increase of Ca+ 2 oscillations after chronic TRPV1 receptor activation with capsaicin in cultured spinal neurons C Larrucea, P Castro, FJ Sepulveda, G Wandersleben, J Roa, LG Aguayo Brain research 1218, 70-76, 2008 | 13 | 2008 |
ß-Amyloid causes depletion of synaptic vesicles leading to neurotransmission failure J Parodi, FJ Sepulveda, J Roa, C Opazo, NC Inestrosa, LG Aguayo J Biol Chem 285, 2506-2514, 2010 | 12 | 2010 |