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Fernando J Sepulveda
Fernando J Sepulveda
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Synaptotoxicity of Alzheimer beta amyloid can be explained by its membrane perforating property
FJ Sepulveda, J Parodi, RW Peoples, C Opazo, LG Aguayo
PloS one 5 (7), e11820, 2010
1912010
β-amyloid causes depletion of synaptic vesicles leading to neurotransmission failure
J Parodi, FJ Sepulveda, J Roa, C Opazo, NC Inestrosa, LG Aguayo
Journal of Biological Chemistry 285 (4), 2506-2514, 2010
1902010
Canonical Wnt3a modulates intracellular calcium and enhances excitatory neurotransmission in hippocampal neurons
ME Avila, FJ Sepúlveda, CF Burgos, G Moraga-Cid, J Parodi, RT Moon, ...
Journal of biological chemistry 285 (24), 18939-18947, 2010
972010
Differential roles of NMDA receptor subtypes NR2A and NR2B in dendritic branch development and requirement of RasGRF1
FJ Sepulveda, FJ Bustos, E Inostroza, FA Zúñiga, RL Neve, M Montecino, ...
Journal of neurophysiology 103 (4), 1758-1770, 2010
872010
Biphasic effects of copper on neurotransmission in rat hippocampal neurons
C Peters, B Muñoz, FJ Sepúlveda, J Urrutia, M Quiroz, S Luza, ...
Journal of Neurochemistry 119 (1), 78-88, 2011
742011
Nature of the neurotoxic membrane actions of amyloid-β on hippocampal neurons in Alzheimer's disease
FJ Sepúlveda, H Fierro, E Fernandez, C Castillo, RW Peoples, C Opazo, ...
Neurobiology of aging 35 (3), 472-481, 2014
702014
Nature of the neurotoxic membrane actions of amyloid-β on hippocampal neurons in Alzheimer's disease
FJ Sepúlveda, H Fierro, E Fernandez, C Castillo, RW Peoples, C Opazo, ...
Neurobiology of aging 35 (3), 472-481, 2014
702014
Effect of cholesterol on membrane fluidity and association of Aβ oligomers and subsequent neuronal damage: A Double-Edged Sword
EJ Fernández-Pérez, FJ Sepúlveda, C Peters, D Bascuñán, ...
Frontiers in aging neuroscience 10, 226, 2018
662018
Glial hypothalamic inhibition of GLUT2 expression alters satiety, impacting eating behavior
MJ Barahona, P Llanos, A Recabal, K Escobar‐Acuña, R Elizondo‐Vega, ...
Glia 66 (3), 592-605, 2018
532018
Soluble Aβ 1-40 peptide increases excitatory neurotransmission and induces epileptiform activity in hippocampal neurons
ME Cuevas, H Haensgen, FJ Sepúlveda, G Zegers, J Roa, C Opazo, ...
Journal of Alzheimer's Disease 23 (4), 673-687, 2011
392011
Regulation of glycinergic and GABAergic synaptogenesis by brain-derived neurotrophic factor in developing spinal neurons
MA Carrasco, P Castro, FJ Sepulveda, JC Tapia, K Gatica, MI Davis, ...
Neuroscience 145 (2), 484-494, 2007
392007
Role of membrane GM1 on early neuronal membrane actions of Aβ during onset of Alzheimer's disease
EJ Fernández-Pérez, FJ Sepúlveda, R Peoples, LG Aguayo
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1863 (12 …, 2017
362017
Adenovirus-mediated suppression of hypothalamic glucokinase affects feeding behavior
RM Uranga, C Millán, MJ Barahona, A Recabal, M Salgado, F Martinez, ...
Scientific Reports 7 (1), 3697, 2017
292017
Alzheimer β-amyloid blocks epileptiform activity in hippocampal neurons
FJ Sepúlveda, C Opazo, LG Aguayo
Molecular and Cellular Neuroscience 41 (4), 420-428, 2009
242009
Ibuprofen inhibits the synaptic failure induced by the amyloid-β peptide in hippocampal neurons
MP Zurita, G Munoz, FJ Sepulveda, P Gomez, C Castillo, CF Burgos, ...
Journal of Alzheimer's Disease 35 (3), 463-473, 2013
192013
Copper-uptake is critical for the down regulation of synapsin and dynamin induced by neocuproine: modulation of synaptic activity in hippocampal neurons
PA Castro, A Ramirez, FJ Sepúlveda, C Peters, H Fierro, J Waldron, ...
Frontiers in Aging Neuroscience 6, 319, 2014
172014
The level of NMDA receptor in the membrane modulates amyloid-β association and perforation
C Peters, FJ Sepúlveda, EJ Fernández-Pérez, RW Peoples, LG Aguayo
Journal of Alzheimer's Disease 53 (1), 197-207, 2016
162016
Anti‐homeostatic synaptic plasticity of glycine receptor function after chronic strychnine in developing cultured mouse spinal neurons
MA Carrasco, PA Castro, FJ Sepulveda, M Cuevas, JC Tapia, P Izaurieta, ...
Journal of neurochemistry 100 (5), 1143-1154, 2007
162007
Sustained increase of Ca+ 2 oscillations after chronic TRPV1 receptor activation with capsaicin in cultured spinal neurons
C Larrucea, P Castro, FJ Sepulveda, G Wandersleben, J Roa, LG Aguayo
Brain research 1218, 70-76, 2008
132008
ß-Amyloid causes depletion of synaptic vesicles leading to neurotransmission failure
J Parodi, FJ Sepulveda, J Roa, C Opazo, NC Inestrosa, LG Aguayo
J Biol Chem 285, 2506-2514, 2010
122010
El sistema no puede realizar la operación en estos momentos. Inténtalo de nuevo más tarde.
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