David Wyllie
David Wyllie
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Cited by
Modulation of synaptic transmission and long-term potentiation: effects on paired pulse facilitation and EPSC variance in the CA1 region of the hippocampus
T Manabe, DJ Wyllie, DJ Perkel, RA Nicoll
Journal of neurophysiology 70 (4), 1451-1459, 1993
Synaptic NMDA receptor activity boosts intrinsic antioxidant defenses
S Papadia, FX Soriano, F Léveillé, MA Martel, KA Dakin, HH Hansen, ...
Nature neuroscience 11 (4), 476-487, 2008
Subunit‐specific gating controls rat NR1/NR2A and NR1/NR2B NMDA channel kinetics and synaptic signalling profiles
K Erreger, SM Dravid, TG Banke, DJA Wyllie, SF Traynelis
The Journal of physiology 563 (2), 345-358, 2005
Mutant induced pluripotent stem cell lines recapitulate aspects of TDP-43 proteinopathies and reveal cell-specific vulnerability
B Bilican, A Serio, SJ Barmada, AL Nishimura, GJ Sullivan, M Carrasco, ...
Proceedings of the National Academy of Sciences 109 (15), 5803-5808, 2012
Identification of amino acid residues of the NR2A subunit that control glutamate potency in recombinant NR1/NR2A NMDA receptors
LC Anson, PE Chen, DJA Wyllie, D Colquhoun, R Schoepfer
Journal of Neuroscience 18 (2), 581-589, 1998
Single‐channel activations and concentration jumps: comparison of recombinant NR1a/NR2A and NR1a/NR2D NMDA receptors
DJA Wyllie, P Behe, D Colquhoun
The Journal of physiology 510 (1), 1-18, 1998
Influence of GluN2 subunit identity on NMDA receptor function
DJA Wyllie, MR Livesey, GE Hardingham
Neuropharmacology 74, 4-17, 2013
Mitochondrial calcium uniporter Mcu controls excitotoxicity and is transcriptionally repressed by neuroprotective nuclear calcium signals
J Qiu, YW Tan, AM Hagenston, MA Martel, N Kneisel, PA Skehel, ...
Nature communications 4 (1), 2034, 2013
Neurons and neuronal activity control gene expression in astrocytes to regulate their development and metabolism
P Hasel, O Dando, Z Jiwaji, P Baxter, AC Todd, S Heron, NM Márkus, ...
Nature communications 8 (1), 15132, 2017
Determination of NMDA NR1 subunit copy number in recombinant NMDA receptors
P Béhé, P Stern, DJA Wyllie, M Nassar, R Schoepfer, D Colquhoun
Proceedings of the Royal Society of London. Series B: Biological Sciences …, 1995
Glutamate receptor gating
K Erreger, PE Chen, DJA Wyllie, SF Traynelis
Critical Reviews™ in Neurobiology 16 (3), 2004
The subtype of GluN2 C-terminal domain determines the response to excitotoxic insults
MA Martel, TJ Ryan, KFS Bell, JH Fowler, A McMahon, B Al-Mubarak, ...
Neuron 74 (3), 543-556, 2012
Structural features of the glutamate binding site in recombinant NR1/NR2A N-methyl-D-aspartate receptors determined by site-directed mutagenesis and molecular modeling
PE Chen, MT Geballe, PJ Stansfeld, AR Johnston, H Yuan, AL Jacob, ...
Molecular pharmacology 67 (5), 1470-1484, 2005
Subunit-specific agonist activity at NR2A-, NR2B-, NR2C-, and NR2D-containing N-methyl-D-aspartate glutamate receptors
K Erreger, MT Geballe, A Kristensen, PE Chen, KB Hansen, CJ Lee, ...
Molecular pharmacology 72 (4), 907-920, 2007
In developing hippocampal neurons, NR2B-containing N-methyl-D-aspartate receptors (NMDARs) can mediate signaling to neuronal survival and synaptic potentiation, as well as …
MA Martel, DJA Wyllie, GE Hardingham
Neuroscience 158 (1), 334-343, 2009
Specific targeting of pro-death NMDA receptor signals with differing reliance on the NR2B PDZ ligand
FX Soriano, MA Martel, S Papadia, A Vaslin, P Baxter, C Rickman, ...
Journal of Neuroscience 28 (42), 10696-10710, 2008
Dynamin I phosphorylation by GSK3 controls activity-dependent bulk endocytosis of synaptic vesicles
EL Clayton, N Sue, KJ Smillie, T O'Leary, N Bache, G Cheung, AR Cole, ...
Nature neuroscience 13 (7), 845-851, 2010
Neuronal development is promoted by weakened intrinsic antioxidant defences due to epigenetic repression of Nrf2
KFS Bell, B Al-Mubarak, MA Martel, S McKay, N Wheelan, P Hasel, ...
Nature communications 6 (1), 7066, 2015
Activation of glutamate receptors and glutamate uptake in identified macroglial cells in rat cerebellar cultures.
DJ Wyllie, A Mathie, CJ Symonds, SG Cull‐Candy
The Journal of Physiology 432 (1), 235-258, 1991
C9ORF72 repeat expansion causes vulnerability of motor neurons to Ca2+-permeable AMPA receptor-mediated excitotoxicity
BT Selvaraj, MR Livesey, C Zhao, JM Gregory, OT James, EM Cleary, ...
Nature communications 9 (1), 347, 2018
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