Advances in the Biofabrication of 3D Skin in vitro: Healthy and Pathological Models MJ Randall, A Jüngel, M Rimann, K Wuertz-Kozak Frontiers in bioengineering and biotechnology 6, 154, 2018 | 171 | 2018 |
Mitochondrial ROS induced by chronic ethanol exposure promote hyper-activation of the NLRP3 inflammasome LR Hoyt, MJ Randall, JL Ather, DP DePuccio, CC Landry, X Qian, ... Redox biology 12, 883-896, 2017 | 117 | 2017 |
IL-1/inhibitory κB kinase ε–induced glycolysis augment epithelial effector function and promote allergic airways disease X Qian, R Aboushousha, C van de Wetering, SB Chia, E Amiel, ... Journal of Allergy and Clinical Immunology 142 (2), 435-450. e10, 2018 | 50 | 2018 |
Ethanol and other short-chain alcohols inhibit NLRP3 inflammasome activation through protein tyrosine phosphatase stimulation LR Hoyt, JL Ather, MJ Randall, DP DePuccio, CC Landry, MD Wewers, ... The Journal of Immunology 197 (4), 1322-1334, 2016 | 50 | 2016 |
The tobacco smoke component, acrolein, suppresses innate macrophage responses by direct alkylation of c-Jun N-terminal kinase M Hristova, PC Spiess, DI Kasahara, MJ Randall, B Deng, A van der Vliet American journal of respiratory cell and molecular biology 46 (1), 23-33, 2012 | 47 | 2012 |
Acrolein exposure suppresses antigen-induced pulmonary inflammation PC Spiess, D Kasahara, A Habibovic, M Hristova, MJ Randall, ... Respiratory research 14, 1-14, 2013 | 41 | 2013 |
Acrolein-induced activation of mitogen-activated protein kinase signaling is mediated by alkylation of thioredoxin reductase and thioredoxin 1 MJ Randall, PC Spiess, M Hristova, RJ Hondal, A van der Vliet Redox biology 1 (1), 265-275, 2013 | 40 | 2013 |
Adaptation to acrolein through upregulating the protection by glutathione in human bronchial epithelial cells: the materialization of the hormesis concept MM Sthijns, MJ Randall, A Bast, GRMM Haenen Biochemical and biophysical research communications 446 (4), 1029-1034, 2014 | 36 | 2014 |
Protein alkylation by the α, β-unsaturated aldehyde acrolein. A reversible mechanism of electrophile signaling? MJ Randall, M Hristova, A van der Vliet FEBS letters 587 (23), 3808-3814, 2013 | 36 | 2013 |
Weight loss decreases inherent and allergic methacholine hyperresponsiveness in mouse models of diet-induced obese asthma JL Ather, M Chung, LR Hoyt, MJ Randall, A Georgsdottir, NA Daphtary, ... American journal of respiratory cell and molecular biology 55 (2), 176-187, 2016 | 32 | 2016 |
Ziritaxestat, a novel autotaxin inhibitor, and lung function in idiopathic pulmonary fibrosis: the ISABELA 1 and 2 randomized clinical trials TM Maher, P Ford, KK Brown, U Costabel, V Cottin, SK Danoff, ... Jama 329 (18), 1567-1578, 2023 | 28 | 2023 |
Bacterial lipoproteins constitute the TLR2-stimulating activity of serum amyloid A EJ Burgess, LR Hoyt, MJ Randall, MM Mank, JJ Bivona, PL Eisenhauer, ... The Journal of Immunology 201 (8), 2377-2384, 2018 | 24 | 2018 |
The tobacco smoke component acrolein induces glucocorticoid resistant gene expression via inhibition of histone deacetylase MJ Randall, GRMM Haenen, FG Bouwman, A van der Vliet, A Bast Toxicology letters 240 (1), 43-49, 2016 | 22 | 2016 |
Ablation of Glutaredoxin-1 Modulates House Dust Mite–Induced Allergic Airways Disease in Mice SM Hoffman, X Qian, JD Nolin, DG Chapman, SB Chia, KG Lahue, ... American journal of respiratory cell and molecular biology 55 (3), 377-386, 2016 | 20 | 2016 |
Anti-inflammatory effects of levalbuterol-induced 11β-hydroxysteroid dehydrogenase type 1 activity in airway epithelial cells MJ Randall, SF Kostin, EJ Burgess, LR Hoyt, JL Ather, LK Lundblad, ... Frontiers in Endocrinology 5, 236, 2015 | 14 | 2015 |
Inhalation of the reactive aldehyde acrolein promotes antigen sensitization to ovalbumin and enhances neutrophilic inflammation E O’Brien, PC Spiess, A Habibovic, M Hristova, RA Bauer, MJ Randall, ... Journal of immunotoxicology 13 (2), 191-197, 2016 | 11 | 2016 |
ISABELA 1 and 2 investigators. ziritaxestat, a novel autotaxin inhibitor, and lung function in idiopathic pulmonary fibrosis: the ISABELA 1 and 2 randomized clinical trials TM Maher, P Ford, KK Brown, U Costabel, V Cottin, SK Danoff, ... JAMA 329 (18), 1567-1578, 2023 | 8 | 2023 |
A 24‐Week, Phase IIa, Randomized, Double‐Blind, Placebo‐Controlled Study of Ziritaxestat in Early Diffuse Cutaneous Systemic Sclerosis D Khanna, CP Denton, DE Furst, MD Mayes, M Matucci‐Cerinic, V Smith, ... Arthritis & Rheumatology 75 (8), 1434-1444, 2023 | 6 | 2023 |
Assessment of a relationship between prognostic biomarkers and treatment response in ISABELA1 &2 IPF cohorts M Randall, S De Bernard, I Seghers, N Verbruggen, S Lim, ... European Respiratory Journal 60 (suppl 66), 2022 | 1 | 2022 |
Uricase Inhibits Nitrogen Dioxide–Promoted Allergic Sensitization to Inhaled Ovalbumin Independent of Uric Acid Catabolism JL Ather, EJ Burgess, LR Hoyt, MJ Randall, MK Mandal, DE Matthews, ... The Journal of Immunology 197 (5), 1720-1732, 2016 | 1 | 2016 |