| Antibiotics induce redox-related physiological alterations as part of their lethality DJ Dwyer*, PA Belenky*, JH Yang*, IC MacDonald, JD Martell, ... Proceedings of the National Academy of Sciences 111 (20), E2100-E2109, 2014 | 900 | 2014 |
| Antibiotic efficacy is linked to bacterial cellular respiration MA Lobritz*, P Belenky*, CBM Porter, A Gutierrez, JH Yang, EG Schwarz, ... Proceedings of the National Academy of Sciences, 201509743, 2015 | 711 | 2015 |
| Carbon Sources Tune Antibiotic Susceptibility in Pseudomonas aeruginosa via Tricarboxylic Acid Cycle Control S Meylan, CBM Porter*, JH Yang*, P Belenky, A Gutierrez, MA Lobritz, ... Cell Chemical Biology, 2017 | 323* | 2017 |
| A white-box machine learning approach for revealing antibiotic mechanisms of action JH Yang, SN Wright, M Hamblin, D McCloskey, MA Alcantar, ... Cell 177 (6), 1649-1661. e9, 2019 | 289 | 2019 |
| Clinically relevant mutations in core metabolic genes confer antibiotic resistance AJ Lopatkin, SC Bening, AL Manson, JM Stokes, MA Kohanski, ... Science 371 (6531), eaba0862, 2021 | 258 | 2021 |
| Antibiotic-Induced Changes to the Host Metabolic Environment Inhibit Drug Efficacy and Alter Immune Function JH Yang*, P Bhargava*, D McCloskey, N Mao, BO Palsson, JJ Collins Cell Host & Microbe, 2017 | 245 | 2017 |
| Bacterial metabolic state more accurately predicts antibiotic lethality than growth rate AJ Lopatkin, JM Stokes, EJ Zheng, JH Yang, MK Takahashi, L You, ... Nature Microbiology 4 (12), 2109-2117, 2019 | 210 | 2019 |
| Regulation of nuclear PKA revealed by spatiotemporal manipulation of cyclic AMP V Sample*, LM DiPilato*, JH Yang*, Q Ni, JJ Saucerman, J Zhang, ... Nature chemical biology 8 (4), 375-382, 2012 | 150 | 2012 |
| Antibiotic efficacy—context matters JH Yang*, SC Bening*, JJ Collins Current Opinion in Microbiology 39, 73-80, 2017 | 98 | 2017 |
| Applications of machine learning to the problem of antimicrobial resistance: An emerging model for translational research MN Anahtar, JH Yang, S Kanjilal Journal of Clinical Microbiology, JCM. 01260-20, 2021 | 81 | 2021 |
| Comparing McRoberts' and Rubin's maneuvers for initial management of shoulder dystocia: an objective evaluation ED Gurewitsch, EJ Kim, JH Yang, KE Outland, MK McDonald, RH Allen American journal of obstetrics and gynecology 192 (1), 153-160, 2005 | 76 | 2005 |
| Computational models reduce complexity and accelerate insight into cardiac signaling networks JH Yang, JJ Saucerman Circulation research 108 (1), 85-97, 2011 | 61 | 2011 |
| PKA catalytic subunit compartmentation regulates contractile and hypertrophic responses to β-adrenergic signaling JH Yang, RK Polanowska-Grabowska, JS Smith, CW Shields IV, ... Journal of molecular and cellular cardiology 66, 83-93, 2014 | 57 | 2014 |
| Phospholemman is a negative feed-forward regulator of Ca2+ in β-adrenergic signaling, accelerating β-adrenergic inotropy JH Yang, JJ Saucerman Journal of molecular and cellular cardiology 52 (5), 1048-1055, 2012 | 44 | 2012 |
| Lethality of MalE-LacZ hybrid protein shares mechanistic attributes with oxidative component of antibiotic lethality N Takahashi*, CC Gruber*, JH Yang, X Liu, D Braff, CN Yashaswini, ... Proceedings of the National Academy of Sciences, 201707466, 2017 | 41 | 2017 |
| Digital Insights Into Nucleotide Metabolism and Antibiotic Treatment Failure AJ Lopatkin*, JH Yang* Frontiers in Digital Health 3 (583468), 1-12, 2021 | 27 | 2021 |
| Biomonitoring and precision health in deep space supported by artificial intelligence RT Scott, LM Sanders, EL Antonsen, JJA Hastings, S Park, G Mackintosh, ... Nature Machine Intelligence 5 (3), 196-207, 2023 | 23 | 2023 |
| A comprehensive update to the Mycobacterium tuberculosis H37Rv reference genome P Chitale, AD Lemenze, EC Fogarty, A Shah, C Grady, AR Odom-Mabey, ... Nature communications 13 (1), 7068, 2022 | 22 | 2022 |
| Growth and stress tolerance comprise independent metabolic strategies critical for Staphylococcus aureus infection GL Kim, TA Hooven, J Norambuena, B Li, JM Boyd, JH Yang, D Parker mbio 12 (3), 10.1128/mbio. 00814-21, 2021 | 21 | 2021 |
| Biological research and self-driving labs in deep space supported by artificial intelligence LM Sanders, RT Scott, JH Yang, AA Qutub, H Garcia Martin, DC Berrios, ... Nature Machine Intelligence 5 (3), 208-219, 2023 | 19 | 2023 |
James J CollinsMIT; Wyss Institute, Harvard; Broad Institute of MIT & HarvardVerified email at mit.edu
