Tony Velkov
Tony Velkov
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Structure− activity relationships of polymyxin antibiotics
T Velkov, PE Thompson, RL Nation, J Li
Journal of medicinal chemistry 53 (5), 1898-1916, 2010
Pharmacology of polymyxins: new insights into an ‘old’class of antibiotics
T Velkov, KD Roberts, RL Nation, PE Thompson, J Li
Future microbiology 8 (6), 711-724, 2013
Colistin and polymyxin B: peas in a pod, or chalk and cheese?
RL Nation, T Velkov, J Li
Clinical infectious diseases 59 (1), 88-94, 2014
A secondary mode of action of polymyxins against Gram-negative bacteria involves the inhibition of NADH-quinone oxidoreductase activity
ZZ Deris, J Akter, S Sivanesan, KD Roberts, PE Thompson, RL Nation, ...
The Journal of antibiotics 67 (2), 147-151, 2014
The rise and spread of mcr plasmid-mediated polymyxin resistance
SC Nang, J Li, T Velkov
Critical reviews in microbiology 45 (2), 131-161, 2019
Pharmacokinetics/pharmacodynamics of colistin and polymyxin B: are we there yet?
TB Tran, T Velkov, RL Nation, A Forrest, BT Tsuji, PJ Bergen, J Li
International journal of antimicrobial agents 48 (6), 592-597, 2016
Antimicrobial activity and toxicity of the major lipopeptide components of polymyxin B and colistin: last-line antibiotics against multidrug-resistant Gram-negative bacteria
KD Roberts, MAK Azad, J Wang, AS Horne, PE Thompson, RL Nation, ...
ACS infectious diseases 1 (11), 568-575, 2015
Allosteric folding correction of F508del and rare CFTR mutants by elexacaftor-tezacaftor-ivacaftor (Trikafta) combination
G Veit, A Roldan, MA Hancock, DF Da Fonte, H Xu, M Hussein, S Frenkiel, ...
JCI insight 5 (18), 2020
Teaching ‘old’polymyxins new tricks: new-generation lipopeptides targeting Gram-negative ‘superbugs’
T Velkov, KD Roberts, RL Nation, J Wang, PE Thompson, J Li
ACS chemical biology 9 (5), 1172-1177, 2014
Head and flagella subcompartmental proteomic analysis of human spermatozoa
MA Baker, N Naumovski, L Hetherington, A Weinberg, T Velkov, RJ Aitken
Proteomics 13 (1), 61-74, 2013
Probing the penetration of antimicrobial polymyxin lipopeptides into gram-negative bacteria
ZZ Deris, JD Swarbrick, KD Roberts, MAK Azad, J Akter, AS Horne, ...
Bioconjugate chemistry 25 (4), 750-760, 2014
Rescuing the last-line polymyxins: achievements and challenges
SC Nang, MAK Azad, T Velkov, QT Zhou, J Li
Pharmacological reviews 73 (2), 679-728, 2021
The combination of colistin and doripenem is synergistic against Klebsiella pneumoniae at multiple inocula and suppresses colistin resistance in an in vitro pharmacokinetic …
ZZ Deris, HH Yu, K Davis, RL Soon, J Jacob, CK Ku, A Poudyal, ...
Antimicrobial agents and chemotherapy 56 (10), 5103-5112, 2012
Lycopene attenuates colistin-induced nephrotoxicity in mice via activation of the Nrf2/HO-1 pathway
C Dai, S Tang, S Deng, S Zhang, Y Zhou, T Velkov, J Li, X Xiao
Antimicrobial agents and chemotherapy 59 (1), 579-585, 2015
Chloroquine ameliorates carbon tetrachloride-induced acute liver injury in mice via the concomitant inhibition of inflammation and induction of apoptosis
C Dai, X Xiao, D Li, S Tun, Y Wang, T Velkov, S Tang
Cell death & disease 9 (12), 1164, 2018
Polymyxin B induces apoptosis in kidney proximal tubular cells
MAK Azad, BA Finnin, A Poudyal, K Davis, J Li, PA Hill, RL Nation, ...
Antimicrobial agents and chemotherapy 57 (9), 4329-4335, 2013
Inhaled anti-infective chemotherapy for respiratory tract infections: successes, challenges and the road ahead
T Velkov, NA Rahim, QT Zhou, HK Chan, J Li
Advanced drug delivery reviews 85, 65-82, 2015
Two mechanisms of killing of Pseudomonas aeruginosa by tobramycin assessed at multiple inocula via mechanism-based modeling
JB Bulitta, NS Ly, CB Landersdorfer, NA Wanigaratne, T Velkov, R Yadav, ...
Antimicrobial agents and chemotherapy 59 (4), 2315-2327, 2015
Pharmacokinetics of four different brands of colistimethate and formed colistin in rats
H He, JC Li, RL Nation, J Jacob, G Chen, HJ Lee, BT Tsuji, PE Thompson, ...
Journal of Antimicrobial Chemotherapy 68 (10), 2311-2317, 2013
Synergistic killing of NDM-producing MDR Klebsiella pneumoniae by two ‘old’ antibiotics—polymyxin B and chloramphenicol
N Abdul Rahim, SE Cheah, MD Johnson, H Yu, HE Sidjabat, J Boyce, ...
Journal of Antimicrobial Chemotherapy 70 (9), 2589-2597, 2015
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