| Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity Y Echelard, DJ Epstein, B St-Jacques, L Shen, J Mohler, JA McMahon, ... Cell 75 (7), 1417-1430, 1993 | 2750 | 1993 |
| Splotch (Sp2H), a mutation affecting development of the mouse neural tube, shows a deletion within the paired homeodomain of Pax-3 DJ Epstein, M Vekemans, P Gros Cell 67 (4), 767-774, 1991 | 810 | 1991 |
| Gli2 is required for induction of floor plate and adjacent cells, but not most ventral neurons in the mouse central nervous system MP Matise, DJ Epstein, HL Park, KA Platt, AL Joyner Development 125 (15), 2759-2770, 1998 | 590 | 1998 |
| Characterization of Wnt gene expression in developing and postnatal hair follicles and identification of Wnt5a as a target of Sonic hedgehog in hair follicle morphogenesis S Reddy, T Andl, A Bagasra, MM Lu, DJ Epstein, EE Morrisey, SE Millar Mechanisms of development 107 (1-2), 69-82, 2001 | 547 | 2001 |
| A role for Gbx2 in repression of Otx2 and positioning the mid/hindbrain organizer S Millet, K Campbell, DJ Epstein, K Losos, E Harris, AL Joyner Nature 401 (6749), 161-164, 1999 | 374 | 1999 |
| Wnt/β-catenin signaling promotes expansion of Isl-1–positive cardiac progenitor cells through regulation of FGF signaling ED Cohen, Z Wang, JJ Lepore, MM Lu, MM Taketo, DJ Epstein, ... The Journal of clinical investigation 117 (7), 1794-1804, 2007 | 331 | 2007 |
| Wnt-dependent regulation of inner ear morphogenesis is balanced by the opposing and supporting roles of Shh MM Riccomagno, S Takada, DJ Epstein Genes & development 19 (13), 1612-1623, 2005 | 283 | 2005 |
| Specification of the mammalian cochlea is dependent on Sonic hedgehog MM Riccomagno, L Martinu, M Mulheisen, DK Wu, DJ Epstein Genes & development 16 (18), 2365-2378, 2002 | 280 | 2002 |
| Cloning, expression, and chromosomal location of SHH and IHH: two human homologues of the Drosophila segment polarity gene hedgehog V Marigo, DJ Roberts, SMK Lee, O Tsukurov, T Levi, JM Gastier, ... Genomics 28 (1), 44-51, 1995 | 274 | 1995 |
| A functional screen for sonic hedgehog regulatory elements across a 1 Mb interval identifies long-range ventral forebrain enhancers Y Jeong, K El-Jaick, E Roessler, M Muenke, DJ Epstein Oxford University Press for The Company of Biologists Limited 133 (4), 761-772, 2006 | 271 | 2006 |
| Neural crest stem cell maintenance by combinatorial Wnt and BMP signaling M Kléber, HY Lee, H Wurdak, J Buchstaller, MM Riccomagno, LM Ittner, ... The Journal of cell biology 169 (2), 309-320, 2005 | 240 | 2005 |
| Myf5 is a direct target of long-range Shh signaling and Gli regulation for muscle specification MK Gustafsson, H Pan, DF Pinney, Y Liu, A Lewandowski, DJ Epstein, ... Genes & development 16 (1), 114-126, 2002 | 237 | 2002 |
| A mutation within intron 3 of the Pax-3 gene produces aberrantly spliced mRNA transcripts in the splotch (Sp) mouse mutant. DJ Epstein, KJ Vogan, DG Trasler, P Gros Proceedings of the National Academy of Sciences 90 (2), 532-536, 1993 | 230 | 1993 |
| Regulation of a remote Shh forebrain enhancer by the Six3 homeoprotein Y Jeong, FC Leskow, K El-Jaick, E Roessler, M Muenke, A Yocum, ... Nature genetics 40 (11), 1348-1353, 2008 | 227 | 2008 |
| Antagonizing cAMP-dependent protein kinase A in the dorsal CNS activates a conserved Sonic hedgehog signaling pathway DJ Epstein, E Martí, MP Scott, AP McMahon Development 122 (9), 2885-2894, 1996 | 219 | 1996 |
| Regionalization of Sonic hedgehog transcription along the anteroposterior axis of the mouse central nervous system is regulated by Hnf3-dependent and … DJ Epstein, AP McMahon, AL Joyner Development 126 (2), 281-292, 1999 | 207 | 1999 |
| Genetic interaction between members of the Vangl family causes neural tube defects in mice E Torban, AM Patenaude, S Leclerc, S Rakowiecki, S Gauthier, ... Proceedings of the National Academy of Sciences 105 (9), 3449-3454, 2008 | 202 | 2008 |
| Haploinsufficiency of Six3 fails to activate Sonic hedgehog expression in the ventral forebrain and causes holoprosencephaly X Geng, C Speirs, O Lagutin, A Inbal, W Liu, L Solnica-Krezel, Y Jeong, ... Developmental cell 15 (2), 236-247, 2008 | 197 | 2008 |
| Cre-mediated excision of Fgf8 in the Tbx1 expression domain reveals a critical role for Fgf8 in cardiovascular development in the mouse CB Brown, JM Wenning, MM Lu, DJ Epstein, EN Meyers, JA Epstein Developmental biology 267 (1), 190-202, 2004 | 161 | 2004 |
| FoxF1 and FoxL1 link hedgehog signaling and the control of epithelial proliferation in the developing stomach and intestine BB Madison, LB McKenna, D Dolson, DJ Epstein, KH Kaestner Journal of biological chemistry 284 (9), 5936-5944, 2009 | 150 | 2009 |
