Gut microbiome modulates response to anti–PD-1 immunotherapy in melanoma patients V Gopalakrishnan, CN Spencer, L Nezi, A Reuben, MC Andrews, ... Science 359 (6371), 97-103, 2018 | 3855 | 2018 |
Genomic classification of cutaneous melanoma R Akbani, KC Akdemir, BA Aksoy, M Albert, A Ally, SB Amin, H Arachchi, ... Cell 161 (7), 1681-1696, 2015 | 2674 | 2015 |
DNA breaks and chromosome pulverization from errors in mitosis K Crasta, NJ Ganem, R Dagher, AB Lantermann, EV Ivanova, Y Pan, ... Nature 482 (7383), 53-58, 2012 | 1302 | 2012 |
Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function A Viale, P Pettazzoni, CA Lyssiotis, H Ying, N Sánchez, M Marchesini, ... Nature 514 (7524), 628-632, 2014 | 1178 | 2014 |
The Mad1/Mad2 complex as a template for Mad2 activation in the spindle assembly checkpoint A De Antoni, CG Pearson, D Cimini, JC Canman, V Sala, L Nezi, ... Current Biology 15 (3), 214-225, 2005 | 560 | 2005 |
Dietary fiber and probiotics influence the gut microbiome and melanoma immunotherapy response CN Spencer, JL McQuade, V Gopalakrishnan, JA McCulloch, M Vetizou, ... Science 374 (6575), 1632-1640, 2021 | 421 | 2021 |
Passenger deletions generate therapeutic vulnerabilities in cancer FL Muller, S Colla, E Aquilanti, VE Manzo, G Genovese, J Lee, ... Nature 488 (7411), 337-342, 2012 | 362 | 2012 |
Gut microbiota signatures are associated with toxicity to combined CTLA-4 and PD-1 blockade MC Andrews, CPM Duong, V Gopalakrishnan, V Iebba, WS Chen, ... Nature medicine 27 (8), 1432-1441, 2021 | 253 | 2021 |
Sister chromatid tension and the spindle assembly checkpoint L Nezi, A Musacchio Current opinion in cell biology 21 (6), 785-795, 2009 | 205 | 2009 |
Reporting guidelines for human microbiome research: the STORMS checklist C Mirzayi, A Renson, Genomic Standards Consortium, ... Nature medicine 27 (11), 1885-1892, 2021 | 201 | 2021 |
Cross-cohort gut microbiome associations with immune checkpoint inhibitor response in advanced melanoma KA Lee, AM Thomas, LA Bolte, JR Björk, LK de Ruijter, F Armanini, ... Nature medicine 28 (3), 535-544, 2022 | 193 | 2022 |
Accumulation of long-chain fatty acids in the tumor microenvironment drives dysfunction in intrapancreatic CD8+ T cells T Manzo, BM Prentice, KG Anderson, A Raman, A Schalck, GS Codreanu, ... Journal of Experimental Medicine 217 (8), 2020 | 174 | 2020 |
Determinants of conformational dimerization of Mad2 and its inhibition by p31comet M Mapelli, FV Filipp, G Rancati, L Massimiliano, L Nezi, G Stier, ... The EMBO journal 25 (6), 1273-1284, 2006 | 162 | 2006 |
Syndecan 1 is a critical mediator of macropinocytosis in pancreatic cancer W Yao, JL Rose, W Wang, S Seth, H Jiang, A Taguchi, J Liu, L Yan, ... Nature 568 (7752), 410-414, 2019 | 152 | 2019 |
ILF2 is a regulator of RNA splicing and DNA damage response in 1q21-amplified multiple myeloma M Marchesini, Y Ogoti, E Fiorini, AA Samur, L Nezi, M D'Anca, P Storti, ... Cancer cell 32 (1), 88-100. e6, 2017 | 133 | 2017 |
In vivo functional platform targeting patient-derived xenografts identifies WDR5-Myc association as a critical determinant of pancreatic cancer A Carugo, G Genovese, S Seth, L Nezi, JL Rose, D Bossi, A Cicalese, ... Cell reports 16 (1), 133-147, 2016 | 133 | 2016 |
Genomic and immune heterogeneity are associated with differential responses to therapy in melanoma A Reuben, CN Spencer, PA Prieto, V Gopalakrishnan, SM Reddy, ... NPJ genomic medicine 2 (1), 10, 2017 | 131 | 2017 |
Synthetic vulnerabilities of mesenchymal subpopulations in pancreatic cancer G Genovese, A Carugo, J Tepper, FS Robinson, L Li, M Svelto, L Nezi, ... Nature 542 (7641), 362-366, 2017 | 122 | 2017 |
Telomere dysfunction drives aberrant hematopoietic differentiation and myelodysplastic syndrome S Colla, DST Ong, Y Ogoti, M Marchesini, NA Mistry, K Clise-Dwyer, ... Cancer cell 27 (5), 644-657, 2015 | 116 | 2015 |
Genetic events that limit the efficacy of MEK and RTK inhibitor therapies in a mouse model of KRAS-driven pancreatic cancer P Pettazzoni, A Viale, P Shah, A Carugo, H Ying, H Wang, G Genovese, ... Cancer research 75 (6), 1091-1101, 2015 | 86 | 2015 |