Junfei Zhao
Junfei Zhao
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Immune and genomic correlates of response to anti-PD-1 immunotherapy in glioblastoma
J Zhao, AX Chen, RD Gartrell, AM Silverman, L Aparicio, T Chu, ...
Nature medicine 25 (3), 462-469, 2019
New insights into genetic susceptibility of COVID-19: an ACE2 and TMPRSS2 polymorphism analysis
Y Hou, J Zhao, W Martin, A Kallianpur, MK Chung, L Jehi, N Sharifi, ...
BMC medicine 18, 1-8, 2020
TSGene 2.0: an updated literature-based knowledgebase for tumor suppressor genes
M Zhao, P Kim, R Mitra, J Zhao, Z Zhao
Nucleic acids research 44 (D1), D1023-D1031, 2016
Efficient methods for identifying mutated driver pathways in cancer
J Zhao, S Zhang, LY Wu, XS Zhang
Bioinformatics 28 (22), 2940-2947, 2012
Advances in computational approaches for prioritizing driver mutations and significantly mutated genes in cancer genomes
F Cheng, J Zhao, Z Zhao
Briefings in bioinformatics 17 (4), 642-656, 2016
MGMT genomic rearrangements contribute to chemotherapy resistance in gliomas
B Oldrini, N Vaquero-Siguero, Q Mu, P Kroon, Y Zhang, M Galán-Ganga, ...
Nature communications 11 (1), 3883, 2020
Functional interrogation of DNA damage response variants with base editing screens
R Cuella-Martin, SB Hayward, X Fan, X Chen, JW Huang, A Taglialatela, ...
Cell 184 (4), 1081-1097. e19, 2021
Extracellular Matrix/Integrin Signaling Promotes Resistance to Combined Inhibition of HER2 and PI3K in HER2+ Breast CancerECM Promotes Resistance to HER2/PI3K Inhibition
AB Hanker, MV Estrada, G Bianchini, PD Moore, J Zhao, F Cheng, ...
Cancer research 77 (12), 3280-3292, 2017
A gene gravity model for the evolution of cancer genomes: a study of 3,000 cancer genomes across 9 cancer types
F Cheng, C Liu, CC Lin, J Zhao, P Jia, WH Li, Z Zhao
PLoS computational biology 11 (9), e1004497, 2015
Proteome-scale investigation of protein allosteric regulation perturbed by somatic mutations in 7,000 cancer genomes
Q Shen, F Cheng, H Song, W Lu, J Zhao, X An, M Liu, G Chen, Z Zhao, ...
The American Journal of Human Genetics 100 (1), 5-20, 2017
Comprehensive characterization of protein–protein interactions perturbed by disease mutations
F Cheng, J Zhao, Y Wang, W Lu, Z Liu, Y Zhou, WR Martin, R Wang, ...
Nature genetics 53 (3), 342-353, 2021
HDAC inhibitors elicit metabolic reprogramming by targeting super-enhancers in glioblastoma models
TTT Nguyen, Y Zhang, E Shang, C Shu, C Torrini, J Zhao, E Bianchetti, ...
The Journal of clinical investigation 130 (7), 3699-3716, 2020
Very low mutation burden is a feature of inflamed recurrent glioblastomas responsive to cancer immunotherapy
M Gromeier, MC Brown, G Zhang, X Lin, Y Chen, Z Wei, N Beaubier, ...
Nature communications 12 (1), 352, 2021
A network-based drug repositioning infrastructure for precision cancer medicine through targeting significantly mutated genes in the human cancer genomes
F Cheng, J Zhao, M Fooksa, Z Zhao
Journal of the American Medical Informatics Association 23 (4), 681-691, 2016
Systems biology-based investigation of cellular antiviral drug targets identified by gene-trap insertional mutagenesis
F Cheng, JL Murray, J Zhao, J Sheng, Z Zhao, DH Rubin
PLoS computational biology 12 (9), e1005074, 2016
Systematic prioritization of druggable mutations in∼ 5000 genomes across 16 cancer types using a structural genomics-based approach
J Zhao, F Cheng, Y Wang, CL Arteaga, Z Zhao
Molecular & cellular proteomics 15 (2), 642-656, 2016
ccmGDB: a database for cancer cell metabolism genes
P Kim, F Cheng, J Zhao, Z Zhao
Nucleic acids research 44 (D1), D959-D968, 2016
Glioma progression is shaped by genetic evolution and microenvironment interactions
FS Varn, KC Johnson, J Martinek, JT Huse, MLP Nasrallah, P Wesseling, ...
Cell 185 (12), 2184-2199. e16, 2022
Combined HDAC and Bromodomain Protein Inhibition Reprograms Tumor Cell Metabolism and Elicits Synthetic Lethality in GlioblastomaTargeting the Epigenome Reprograms Glioblastoma …
Y Zhang, CT Ishida, W Ishida, SFL Lo, J Zhao, C Shu, E Bianchetti, ...
Clinical Cancer Research 24 (16), 3941-3954, 2018
The possibility of cancer immune editing in gliomas. A critical review
VA Arrieta, B Cacho-Díaz, J Zhao, R Rabadan, L Chen, AM Sonabend
Oncoimmunology 7 (7), e1445458, 2018
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