|Immune and genomic correlates of response to anti-PD-1 immunotherapy in glioblastoma|
J Zhao, AX Chen, RD Gartrell, AM Silverman, L Aparicio, T Chu, ...
Nature medicine 25 (3), 462-469, 2019
|New insights into genetic susceptibility of COVID-19: an ACE2 and TMPRSS2 polymorphism analysis|
Y Hou, J Zhao, W Martin, A Kallianpur, MK Chung, L Jehi, N Sharifi, ...
BMC medicine 18 (1), 1-8, 2020
|TSGene 2.0: an updated literature-based knowledgebase for tumor suppressor genes|
M Zhao, P Kim, R Mitra, J Zhao, Z Zhao
Nucleic acids research 44 (D1), D1023-D1031, 2016
|Efficient methods for identifying mutated driver pathways in cancer|
J Zhao, S Zhang, LY Wu, XS Zhang
Bioinformatics 28 (22), 2940-2947, 2012
|Functional interrogation of DNA damage response variants with base editing screens|
R Cuella-Martin, SB Hayward, X Fan, X Chen, JW Huang, A Taglialatela, ...
Cell 184 (4), 1081-1097. e19, 2021
|Advances in computational approaches for prioritizing driver mutations and significantly mutated genes in cancer genomes|
F Cheng, J Zhao, Z Zhao
Briefings in bioinformatics 17 (4), 642-656, 2016
|Glioma progression is shaped by genetic evolution and microenvironment interactions|
FS Varn, KC Johnson, J Martinek, JT Huse, MLP Nasrallah, P Wesseling, ...
Cell 185 (12), 2184-2199. e16, 2022
|MGMT genomic rearrangements contribute to chemotherapy resistance in gliomas|
B Oldrini, N Vaquero-Siguero, Q Mu, P Kroon, Y Zhang, M Galán-Ganga, ...
Nature communications 11 (1), 3883, 2020
|Comprehensive characterization of protein–protein interactions perturbed by disease mutations|
F Cheng, J Zhao, Y Wang, W Lu, Z Liu, Y Zhou, WR Martin, R Wang, ...
Nature genetics 53 (3), 342-353, 2021
|HDAC inhibitors elicit metabolic reprogramming by targeting super-enhancers in glioblastoma models|
TTT Nguyen, Y Zhang, E Shang, C Shu, C Torrini, J Zhao, E Bianchetti, ...
The Journal of clinical investigation 130 (7), 3699-3716, 2020
|Extracellular Matrix/Integrin Signaling Promotes Resistance to Combined Inhibition of HER2 and PI3K in HER2+ Breast Cancer|
AB Hanker, MV Estrada, G Bianchini, PD Moore, J Zhao, F Cheng, ...
Cancer research 77 (12), 3280-3292, 2017
|A gene gravity model for the evolution of cancer genomes: a study of 3,000 cancer genomes across 9 cancer types|
F Cheng, C Liu, CC Lin, J Zhao, P Jia, WH Li, Z Zhao
PLoS computational biology 11 (9), e1004497, 2015
|Very low mutation burden is a feature of inflamed recurrent glioblastomas responsive to cancer immunotherapy|
M Gromeier, MC Brown, G Zhang, X Lin, Y Chen, Z Wei, N Beaubier, ...
Nature communications 12 (1), 352, 2021
|Proteome-scale investigation of protein allosteric regulation perturbed by somatic mutations in 7,000 cancer genomes|
Q Shen, F Cheng, H Song, W Lu, J Zhao, X An, M Liu, G Chen, Z Zhao, ...
The American Journal of Human Genetics 100 (1), 5-20, 2017
|A MYC and RAS co-activation signature in localized prostate cancer drives bone metastasis and castration resistance|
JM Arriaga, S Panja, M Alshalalfa, J Zhao, M Zou, A Giacobbe, ...
Nature Cancer 1 (11), 1082-1096, 2020
|A network-based drug repositioning infrastructure for precision cancer medicine through targeting significantly mutated genes in the human cancer genomes|
F Cheng, J Zhao, M Fooksa, Z Zhao
Journal of the American Medical Informatics Association 23 (4), 681-691, 2016
|Systematic prioritization of druggable mutations in∼ 5000 genomes across 16 cancer types using a structural genomics-based approach|
J Zhao, F Cheng, Y Wang, CL Arteaga, Z Zhao
Molecular & cellular proteomics 15 (2), 642-656, 2016
|Single-cell characterization of macrophages in glioblastoma reveals MARCO as a mesenchymal pro-tumor marker|
AX Chen, RD Gartrell, J Zhao, PS Upadhyayula, W Zhao, J Yuan, ...
Genome medicine 13 (1), 1-13, 2021
|Systems biology-based investigation of cellular antiviral drug targets identified by gene-trap insertional mutagenesis|
F Cheng, JL Murray, J Zhao, J Sheng, Z Zhao, DH Rubin
PLoS computational biology 12 (9), e1005074, 2016
|ccmGDB: a database for cancer cell metabolism genes|
P Kim, F Cheng, J Zhao, Z Zhao
Nucleic acids research 44 (D1), D959-D968, 2016