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Vikrant Gohil
Vikrant Gohil
Senior Director at Eli Lilly & Co.
Dirección de correo verificada de lilly.com
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Strategies for characterizing sildenafil, vardenafil, tadalafil and their analogues in herbal dietary supplements, and detecting counterfeit products containing these drugs
S Singh, B Prasad, AA Savaliya, RP Shah, VM Gohil, A Kaur
TrAC Trends in Analytical Chemistry 28 (1), 13-28, 2009
2092009
Modulating TNF-α signaling with natural products
AT Paul, VM Gohil, KK Bhutani
Drug discovery today 11 (15-16), 725-732, 2006
1772006
Natural products drug discovery research in India: Status and appraisal
KK Bhutani, VM Gohil
Indian journal of experimental biology 48 (03), 199-207, 2010
1592010
Design, synthesis and biological evaluation of 1, 3, 6-trisubstituted β-carboline derivatives for cytotoxic and anti-leishmanial potential
NA Lunagariya, VM Gohil, V Kushwah, S Neelagiri, S Jain, S Singh, ...
Bioorganic & Medicinal Chemistry Letters 26 (3), 789-794, 2016
462016
Synthesis and anti-leishmanial activity of 1-aryl-β-carboline derivatives against Leishmania donovani
VM Gohil, KG Brahmbhatt, PM Loiseau, KK Bhutani
Bioorganic & Medicinal Chemistry Letters 22 (12), 3905-3907, 2012
422012
Synthesis, biological evaluation and molecular docking of aryl hydrazines and hydrazides for anticancer activity
VM Gohil, SK Agrawal, AK Saxena, D Garg, C Gopimohan, KK Bhutani
CSIR, 2010
162010
Safety, tolerability and pharmacokinetics (pk) of single and multiple doses of alg-010133, an s-antigen transport inhibiting oligonucleotide polymer (stops) for the treatment …
E Gane, MF Yuen, J Yogaratnam, K Le, J Vuong, W Christopher, V Gohil, ...
J Hepatol 75 (Suppl), S741, 2021
72021
THE S-ANTIGEN TRANSPORT-INHIBITING OLIGONUCLEOTIDE POLYMER (STOPS™) ALG-010133 DEMONSTRATES A FAVORABLE PRECLINICAL PROFILE FOR THE TREATMENT OF CHRONIC HEPATITIS B
V Gohil, D Misner, S Chanda, Q Zhang, J Liu, J Hong, R Pandey, ...
Liver 91 (15.7), 930, 2020
42020
Safety, pharmacokinetics, and antiviral activity of the S-antigen Transport Inhibiting Oligonucleotide Polymers (STOPS) drug candidate ALG-010133 in subjects with chronic …
EJ Gane, K Agarwal, MF Yuen, A Jucov, C Schwabe, K Le, S Wang, ...
Journal of Hepatology, S871-S872, 2022
22022
An in vivo duck hepatitis B virus model recapitulates key aspects of nucleic acid polymer treatment outcomes in chronic hepatitis B patients
Y Debing, H Vanrusselt, L Degrauwe, DAS de Oliveira, CK Kariuki, ...
Antiviral Research, 105835, 2024
2024
Best-in-Class Antisense Oligonucleotides Against Hepatitis B Virus Using Next Generation Bridged Nucleic Acid Chemistries Significantly Increases In Vivo Efficacy and Reduces …
D Misner, J Hong, B Filippi, S Chang, M Tu, G Wiki, F Wenz, K Gupta, ...
INTERNATIONAL JOURNAL OF TOXICOLOGY 42 (1), 94-94, 2023
2023
Lack of Translation of Favorable Nonclinical Toxicology Profile of Antisense Oligonucleotide (ASO) ALG-020572 to Chronic Hepatitis B (CHB) Patients
S Chang, D Misner, K Gupta, G Gratz, J Hong, K Le, V Gohil, ...
INTERNATIONAL JOURNAL OF TOXICOLOGY 42 (1), 89-90, 2023
2023
Nonclinical efficacy, pharmacokinetic profile and pharmacokinetic/pharmacodynamic (PK/PD) correlation of ALG-125755, a GalNAc-conjugated siRNA, for functional cure of chronic …
K Gupta, M Fitzgerald, K Le, V Gohil, S Mukherjee, D Misner, J Hong, ...
ratio 6245, 0.01, 2022
2022
Safety, pharmacokinetics, and antiviral activity of the S-antigen Transport Inhibiting Oligonucleotide Polymers (STOPS) drug candidate ALG-010133 in subjects with chronic …
EJ Gane, K Agarwal, RMF Yuen, A Jucov, C Schwabe, K Le, S Wang, ...
The International Liver Congress 2022, 22-26 June 2022. Journal of Hepatology, 2022
2022
ALG-020572, a GalNAc-conjugated Antisense Oligonucleotide, Demonstrates In Vivo Efficacy and Favorable Preclinical Profile for the Treatment of Chronic Hepatitis B
K Gupta, J Hong, K Le, D Misner, V Gohil, H Tan, H Kang, M Luo, ...
HEPATOLOGY 74, 503A-503A, 2021
2021
Quantitation of siRNA in Biological Matrices by Liquid Chromatography and High Resolution Accurate Mass Spectrometry (LC/MS-HRAM)
SW Yuanxin Xu Ju Liu, Krishna Aluri, Vikrant Gohil, Chris Tran, Jing Li
ASMS Conference on Mass Spectrometry and Allied Topics 65, 2017
2017
Top-Down Analysis of Penicillin Binding Protein 2a from Methicillin Resistant Staphlococcus Aureus
J Neil, H Cardasis, P Yip, V Gohil, A Cherkassky, J Stephenson
ASMS Conference on Mass Spectrometry and Allied Topics, 2015
2015
Pharmaceutical Biotechnology and Biopharmaceuticals
A Paul, V Gohil, K Bhutani
A Textbook of Molecular Biotechnology, 735-762, 2009
2009
Development of an All-Recombinant Intact Protein Standard for LC-MS Application Development and System Suitability Testing
HL Cardasis, R Viner, V Gohil, K Opperman, S Bechler, J Rogers, K Flook, ...
proteins 1009, 8, 0
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