Organoid Profiling Identifies Common Responders to Chemotherapy in Pancreatic Cancer H Tiriac, P Belleau, DD Engle, D Plenker, A Deschênes, TDD Somerville, ... Cancer discovery 8 (9), 1112-1129, 2018 | 909* | 2018 |
Immunogenic neoantigens derived from gene fusions stimulate T cell responses W Yang, KW Lee, RM Srivastava, F Kuo, C Krishna, D Chowell, ... Nature medicine 25 (5), 767-775, 2019 | 340 | 2019 |
Diverse alterations associated with resistance to KRAS (G12C) inhibition Y Zhao, YR Murciano-Goroff, JY Xue, A Ang, J Lucas, TT Mai, ... Nature 599 (7886), 679-683, 2021 | 294 | 2021 |
Distinct classes of complex structural variation uncovered across thousands of cancer genome graphs K Hadi, X Yao, JM Behr, A Deshpande, C Xanthopoulakis, H Tian, ... Cell 183 (1), 197-210. e32, 2020 | 214 | 2020 |
Genetic determinants of cisplatin resistance in patients with advanced germ cell tumors A Bagrodia, BH Lee, W Lee, EK Cha, JP Sfakianos, G Iyer, EJ Pietzak, ... Journal of Clinical Oncology 34 (33), 4000-4007, 2016 | 173 | 2016 |
Indel variant analysis of short-read sequencing data with Scalpel H Fang, EA Bergmann, K Arora, V Vacic, MC Zody, I Iossifov, JA O'rawe, ... Nature protocols 11 (12), 2529-2548, 2016 | 123 | 2016 |
Genome-wide somatic variant calling using localized colored de Bruijn graphs G Narzisi, A Corvelo, K Arora, EA Bergmann, M Shah, R Musunuri, ... Communications biology 1 (1), 20, 2018 | 111 | 2018 |
Gene silencing in Tribolium castaneum as a tool for the targeted identification of candidate RNAi targets in crop pests E Knorr, E Fishilevich, L Tenbusch, MLF Frey, M Rangasamy, A Billion, ... Scientific reports 8 (1), 2061, 2018 | 109 | 2018 |
Genetic mechanisms of primary chemotherapy resistance in pediatric acute myeloid leukemia NA McNeer, J Philip, H Geiger, RE Ries, VP Lavallee, M Walsh, M Shah, ... Leukemia 33 (8), 1934-1943, 2019 | 108 | 2019 |
PGBD5 promotes site-specific oncogenic mutations in human tumors AG Henssen, R Koche, J Zhuang, E Jiang, C Reed, A Eisenberg, E Still, ... Nature genetics 49 (7), 1005-1014, 2017 | 97 | 2017 |
Conpair: concordance and contamination estimator for matched tumor–normal pairs EA Bergmann, BJ Chen, K Arora, V Vacic, MC Zody Bioinformatics 32 (20), 3196-3198, 2016 | 81 | 2016 |
African ancestry–associated gene expression profiles in triple-negative breast cancer underlie altered tumor biology and clinical outcome in women of African descent R Martini, P Delpe, TR Chu, K Arora, B Lord, A Verma, D Bedi, B Karanam, ... Cancer discovery 12 (11), 2530-2551, 2022 | 79 | 2022 |
Ancestry-driven recalibration of tumor mutational burden and disparate clinical outcomes in response to immune checkpoint inhibitors AH Nassar, E Adib, S Abou Alaiwi, T El Zarif, S Groha, EW Akl, PV Nuzzo, ... Cancer Cell 40 (10), 1161-1172. e5, 2022 | 73 | 2022 |
Deep whole-genome sequencing of 3 cancer cell lines on 2 sequencing platforms K Arora, M Shah, M Johnson, R Sanghvi, J Shelton, K Nagulapalli, ... Scientific reports 9 (1), 19123, 2019 | 45 | 2019 |
Comparing sequencing assays and human-machine analyses in actionable genomics for glioblastoma KO Wrzeszczynski, MO Frank, T Koyama, K Rhrissorrakrai, N Robine, ... Neurology: Genetics 3 (4), e164, 2017 | 45 | 2017 |
Use of chromatin remodeling ATPases as RNAi targets for parental control of western corn rootworm (Diabrotica virgifera virgifera) and Neotropical brown stink bug (Euschistus … E Fishilevich, AM Vélez, C Khajuria, MLF Frey, RL Hamm, H Wang, ... Insect biochemistry and molecular biology 71, 58-71, 2016 | 45 | 2016 |
Differences in prostate cancer genomes by self-reported race: contributions of genetic ancestry, modifiable cancer risk factors, and clinical factors KH Stopsack, S Nandakumar, K Arora, B Nguyen, SE Vasselman, B Nweji, ... Clinical Cancer Research 28 (2), 318-326, 2022 | 42 | 2022 |
Genetic ancestry correlates with somatic differences in a real-world clinical cancer sequencing cohort K Arora, TN Tran, Y Kemel, M Mehine, YL Liu, S Nandakumar, SA Smith, ... Cancer discovery 12 (11), 2552-2565, 2022 | 38 | 2022 |
Whole-genome characterization of lung adenocarcinomas lacking alterations in the RTK/RAS/RAF pathway J Carrot-Zhang, X Yao, S Devarakonda, A Deshpande, JS Damrauer, ... Cell reports 34 (5), 2021 | 31 | 2021 |
Molecular and phenotypic profiling of colorectal cancer patients in West Africa reveals biological insights OI Alatise, GC Knapp, A Sharma, WK Chatila, OA Arowolo, O Olasehinde, ... Nature Communications 12 (1), 6821, 2021 | 30 | 2021 |