| Organoid Profiling Identifies Common Responders to Chemotherapy in Pancreatic Cancer H Tiriac, P Belleau, DD Engle, D Plenker, A Deschênes, TDD Somerville, ... Cancer discovery 8 (9), 1112-1129, 2018 | 700* | 2018 |
| Immunogenic neoantigens derived from gene fusions stimulate T cell responses W Yang, KW Lee, RM Srivastava, F Kuo, C Krishna, D Chowell, ... Nature medicine 25 (5), 767-775, 2019 | 262 | 2019 |
| Genetic determinants of cisplatin resistance in patients with advanced germ cell tumors A Bagrodia, BH Lee, W Lee, EK Cha, JP Sfakianos, G Iyer, EJ Pietzak, ... Journal of Clinical Oncology 34 (33), 4000, 2016 | 148 | 2016 |
| Diverse alterations associated with resistance to KRAS (G12C) inhibition Y Zhao, YR Murciano-Goroff, JY Xue, A Ang, J Lucas, TT Mai, ... Nature 599 (7886), 679-683, 2021 | 141 | 2021 |
| Distinct classes of complex structural variation uncovered across thousands of cancer genome graphs K Hadi, X Yao, JM Behr, A Deshpande, C Xanthopoulakis, H Tian, ... Cell 183 (1), 197-210. e32, 2020 | 139* | 2020 |
| Indel variant analysis of short-read sequencing data with Scalpel H Fang, EA Bergmann, K Arora, V Vacic, MC Zody, I Iossifov, JA O'rawe, ... Nature protocols 11 (12), 2529-2548, 2016 | 105 | 2016 |
| Genome-wide somatic variant calling using localized colored de Bruijn graphs G Narzisi, A Corvelo, K Arora, EA Bergmann, M Shah, R Musunuri, ... Communications biology 1 (1), 20, 2018 | 94 | 2018 |
| Gene silencing in Tribolium castaneum as a tool for the targeted identification of candidate RNAi targets in crop pests E Knorr, E Fishilevich, L Tenbusch, MLF Frey, M Rangasamy, A Billion, ... Scientific reports 8 (1), 2061, 2018 | 92 | 2018 |
| PGBD5 promotes site-specific oncogenic mutations in human tumors AG Henssen, R Koche, J Zhuang, E Jiang, C Reed, A Eisenberg, E Still, ... Nature genetics 49 (7), 1005-1014, 2017 | 80 | 2017 |
| Genetic mechanisms of primary chemotherapy resistance in pediatric acute myeloid leukemia NA McNeer, J Philip, H Geiger, RE Ries, VP Lavallee, M Walsh, M Shah, ... Leukemia 33 (8), 1934-1943, 2019 | 67 | 2019 |
| Conpair: concordance and contamination estimator for matched tumor–normal pairs EA Bergmann, BJ Chen, K Arora, V Vacic, MC Zody Bioinformatics 32 (20), 3196-3198, 2016 | 60 | 2016 |
| Comparing sequencing assays and human-machine analyses in actionable genomics for glioblastoma KO Wrzeszczynski, MO Frank, T Koyama, K Rhrissorrakrai, N Robine, ... Neurology Genetics 3 (4), 2017 | 43 | 2017 |
| Use of chromatin remodeling ATPases as RNAi targets for parental control of western corn rootworm (Diabrotica virgifera virgifera) and Neotropical brown stink bug (Euschistus … E Fishilevich, AM Vélez, C Khajuria, MLF Frey, RL Hamm, H Wang, ... Insect biochemistry and molecular biology 71, 58-71, 2016 | 39 | 2016 |
| Deep whole-genome sequencing of 3 cancer cell lines on 2 sequencing platforms K Arora, M Shah, M Johnson, R Sanghvi, J Shelton, K Nagulapalli, ... Scientific reports 9 (1), 19123, 2019 | 34 | 2019 |
| Ancestry-driven recalibration of tumor mutational burden and disparate clinical outcomes in response to immune checkpoint inhibitors AH Nassar, E Adib, S Abou Alaiwi, T El Zarif, S Groha, EW Akl, PV Nuzzo, ... Cancer Cell 40 (10), 1161-1172. e5, 2022 | 33 | 2022 |
| Integrative genetic analysis of mouse and human AML identifies cooperating disease alleles MA Hatlen, K Arora, V Vacic, EA Grabowska, W Liao, B Riley-Gillis, ... Journal of Experimental Medicine 213 (1), 25-34, 2016 | 26 | 2016 |
| African ancestry–associated gene expression profiles in triple-negative breast cancer underlie altered tumor biology and clinical outcome in women of African descent R Martini, P Delpe, TR Chu, K Arora, B Lord, A Verma, D Bedi, B Karanam, ... Cancer discovery 12 (11), 2530-2551, 2022 | 25 | 2022 |
| Identification of targetable BRAF ΔN486_P490 variant by whole-genome sequencing leading to dabrafenib-induced remission of a BRAF-mutant pancreatic adenocarcinoma KO Wrzeszczynski, S Rahman, MO Frank, K Arora, M Shah, H Geiger, ... Molecular Case Studies 5 (6), a004424, 2019 | 25 | 2019 |
| Differences in prostate cancer genomes by self-reported race: contributions of genetic ancestry, modifiable cancer risk factors, and clinical factors KH Stopsack, S Nandakumar, K Arora, B Nguyen, SE Vasselman, B Nweji, ... Clinical Cancer Research 28 (2), 318-326, 2022 | 24 | 2022 |
| Analytical validation of clinical whole-genome and transcriptome sequencing of patient-derived tumors for reporting targetable variants in cancer KO Wrzeszczynski, V Felice, A Abhyankar, L Kozon, H Geiger, D Manaa, ... The Journal of Molecular Diagnostics 20 (6), 822-835, 2018 | 24 | 2018 |
