Quasi-equilibrium pharmacokinetic model for drugs exhibiting target-mediated drug disposition DE Mager, W Krzyzanski Pharmaceutical research 22, 1589-1596, 2005 | 253 | 2005 |
Mathematical modeling of circadian cortisol concentrations using indirect response models: comparison of several methods A Chakraborty, W Krzyzanski, WJ Jusko Journal of pharmacokinetics and biopharmaceutics 27, 23-43, 1999 | 127 | 1999 |
Pharmacokinetic and pharmacodynamic modeling of recombinant human erythropoietin after multiple subcutaneous doses in healthy subjects W Krzyzanski, WJ Jusko, MC Wacholtz, N Minton, WK Cheung European journal of pharmaceutical sciences 26 (3-4), 295-306, 2005 | 113 | 2005 |
Basic pharmacodynamic models for agents that alter production of natural cells W Krzyzanski, R Ramakrishnan, WJ Jusko Journal of pharmacokinetics and biopharmaceutics 27, 467-489, 1999 | 108 | 1999 |
Pharmacokinetics of anti-hepcidin monoclonal antibody Ab 12B9m and hepcidin in cynomolgus monkeys JJ Xiao, W Krzyzanski, YM Wang, H Li, MJ Rose, M Ma, Y Wu, B Hinkle, ... The AAPS journal 12, 646-657, 2010 | 104 | 2010 |
Selection between Michaelis–Menten and target-mediated drug disposition pharmacokinetic models X Yan, DE Mager, W Krzyzanski Journal of pharmacokinetics and pharmacodynamics 37, 25-47, 2010 | 101 | 2010 |
Pharmacokinetic and pharmacodynamic modeling of recombinant human erythropoietin after intravenous and subcutaneous administration in rats S Woo, W Krzyzanski, WJ Jusko The Journal of pharmacology and experimental therapeutics 319 (3), 1297-1306, 2006 | 82 | 2006 |
Pharmacodynamics-mediated drug disposition (PDMDD) and precursor pool lifespan model for single dose of romiplostim in healthy subjects YMC Wang, W Krzyzanski, S Doshi, JJ Xiao, JJ Pérez-Ruixo, AT Chow The AAPS journal 12, 729-740, 2010 | 80 | 2010 |
Target-mediated pharmacokinetic and pharmacodynamic model of recombinant human erythropoietin (rHuEPO) S Woo, W Krzyzanski, WJ Jusko Journal of pharmacokinetics and pharmacodynamics 34, 849-868, 2007 | 79 | 2007 |
Mathematical formalism for the properties of four basic models of indirect pharmacodynamic responses W Krzyzanski, WJ Jusko Journal of pharmacokinetics and biopharmaceutics 25, 107-123, 1997 | 77 | 1997 |
Pharmacodynamic model for chemotherapy-induced anemia in rats S Woo, W Krzyzanski, WJ Jusko Cancer chemotherapy and pharmacology 62, 123-133, 2008 | 65 | 2008 |
Population modeling of filgrastim PK‐PD in healthy adults following intravenous and subcutaneous administrations W Krzyzanski, P Wiczling, P Lowe, E Pigeolet, M Fink, A Berghout, ... The Journal of Clinical Pharmacology 50 (S9), 101S-112S, 2010 | 60 | 2010 |
Pharmacokinetic model of target-mediated disposition of thrombopoietin F Jin, W Krzyzanski AAPS PharmSci 6, 86-93, 2004 | 56 | 2004 |
Quantitative prediction of human pharmacokinetics for mAbs exhibiting target-mediated disposition AP Singh, W Krzyzanski, SW Martin, G Weber, A Betts, A Ahmad, ... The AAPS journal 17, 389-399, 2015 | 55 | 2015 |
Integrated functions for four basic models of indirect pharmacodynamic response W Krzyzanski, WJ Jusko Journal of pharmaceutical sciences 87 (1), 67-72, 1998 | 55 | 1998 |
Pharmacodynamic analysis of recombinant human erythropoietin effect on reticulocyte production rate and age distribution in healthy subjects JJ Pérez-Ruixo, W Krzyzanski, J Hing Clinical pharmacokinetics 47, 399-415, 2008 | 54 | 2008 |
Assessment of drug interactions relevant to pharmacodynamic indirect response models J Earp, W Krzyzanski, A Chakraborty, MK Zamacona, WJ Jusko Journal of pharmacokinetics and pharmacodynamics 31, 345-380, 2004 | 54 | 2004 |
Pharmacodynamic models for agents that alter production of natural cells with various distributions of lifespans W Krzyzanski, S Woo, WJ Jusko Journal of pharmacokinetics and pharmacodynamics 33, 125-166, 2006 | 53 | 2006 |
Population pharmacokinetic and pharmacodynamic model‐based comparability assessment of a recombinant human epoetin alfa and the biosimilar HX575 X Yan, PJ Lowe, M Fink, A Berghout, S Balser, W Krzyzanski The Journal of Clinical Pharmacology 52 (11), 1624-1644, 2012 | 49 | 2012 |
Pharmacokinetics and pharmacodynamics of erythropoietin receptor in healthy volunteers W Krzyzanski, E Wyska Naunyn-Schmiedeberg's archives of pharmacology 377, 637-645, 2008 | 49 | 2008 |