Yeast HOG1 MAP kinase cascade is regulated by a multistep phosphorelay mechanism in the SLN1–YPD1–SSK1 “two-component” osmosensor F Posas, SM Wurgler-Murphy, T Maeda, EA Witten, TC Thai, H Saito Cell 86 (6), 865-875, 1996 | 1099 | 1996 |
Osmotic activation of the HOG MAPK pathway via Ste11p MAPKKK: scaffold role of Pbs2p MAPKK F Posas, H Saito Science 276 (5319), 1702-1705, 1997 | 712 | 1997 |
Controlling gene expression in response to stress E De Nadal, G Ammerer, F Posas Nature Reviews Genetics 12 (12), 833-845, 2011 | 680 | 2011 |
Response to hyperosmotic stress H Saito, F Posas Genetics 192 (2), 289-318, 2012 | 528 | 2012 |
The transcriptional response of yeast to saline stress F Posas, JR Chambers, JA Heyman, JP Hoeffler, E De Nadal, J Arino Journal of Biological Chemistry 275 (23), 17249-17255, 2000 | 512 | 2000 |
Regulated nucleo/cytoplasmic exchange of HOG1 MAPK requires the importin β homologs NMD5 and XPO1 P Ferrigno, F Posas, D Koepp, H Saito, PA Silver The EMBO journal 17 (19), 5606-5614, 1998 | 511 | 1998 |
The MAPK Hog1 recruits Rpd3 histone deacetylase to activate osmoresponsive genes E De Nadal, M Zapater, PM Alepuz, L Sumoy, G Mas, F Posas Nature 427 (6972), 370-374, 2004 | 414 | 2004 |
Distributed biological computation with multicellular engineered networks S Regot, J Macia, N Conde, K Furukawa, J Kjellén, T Peeters, S Hohmann, ... Nature 469 (7329), 207-211, 2011 | 396 | 2011 |
Activation of the yeast SSK2 MAP kinase kinase kinase by the SSK1 two-component response regulator F Posas, H Saito The EMBO journal 17 (5), 1385-1394, 1998 | 391 | 1998 |
Yeast Cdc42 GTPase and Ste20 PAK-like kinase regulate Sho1-dependent activation of the Hog1 MAPK pathway DC Raitt, F Posas, H Saito The EMBO journal 19 (17), 4623-4631, 2000 | 310 | 2000 |
Hog1 mediates cell-cycle arrest in G1 phase by the dual targeting of Sic1 X Escoté, M Zapater, J Clotet, F Posas Nature cell biology 6 (10), 997-1002, 2004 | 283 | 2004 |
Dealing with osmostress through MAP kinase activation E de Nadal, PM Alepuz, F Posas EMBO reports 3 (8), 735-740, 2002 | 283 | 2002 |
Regulation of the Sko1 transcriptional repressor by the Hog1 MAP kinase in response to osmotic stress M Proft, A Pascual-Ahuir, E de Nadal, J Ariño, R Serrano, F Posas The EMBO journal 20 (5), 1123-1133, 2001 | 277 | 2001 |
A human homolog of the yeast Ssk2/Ssk22 MAP kinase kinase kinases, MTK1, mediates stress-induced activation of the p38 and JNK pathways M Takekawa, F Posas, H Saito The EMBO Journal 16 (16), 4973-4982, 1997 | 259 | 1997 |
Osmostress-induced transcription by Hot1 depends on a Hog1-mediated recruitment of the RNA Pol II PM Alepuz, E de Nadal, M Zapater, G Ammerer, F Posas The EMBO journal 22 (10), 2433-2442, 2003 | 251 | 2003 |
3D-printing of transparent bio-microfluidic devices in PEG-DA A Urrios, C Parra-Cabrera, N Bhattacharjee, AM Gonzalez-Suarez, ... Lab on a Chip 16 (12), 2287-2294, 2016 | 233 | 2016 |
Signal transduction by MAP kinase cascades in budding yeast F Posas, M Takekawa, H Saito Current opinion in microbiology 1 (2), 175-182, 1998 | 228 | 1998 |
The sequential activation of the yeast HOG and SLT2 pathways is required for cell survival to cell wall stress C Bermejo, E Rodríguez, R García, JM Rodríguez-Peña, ... Molecular biology of the cell 19 (3), 1113-1124, 2008 | 223 | 2008 |
The p38 pathway: from biology to cancer therapy A Martínez-Limón, M Joaquin, M Caballero, F Posas, E De Nadal International journal of molecular sciences 21 (6), 1913, 2020 | 213 | 2020 |
Targeting the MEF2-like transcription factor Smp1 by the stress-activated Hog1 mitogen-activated protein kinase E Nadal, L Casadomé, F Posas Molecular and cellular biology 23 (1), 229-237, 2003 | 206 | 2003 |