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Brent Segelke
Brent Segelke
Bionanomaterials Group Leader, Lawrence Livermore National Laboratory
Dirección de correo verificada de llnl.gov - Página principal
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Crystal structure of mouse CD1: an MHC-like fold with a large hydrophobic binding groove
ZH Zeng, AR Castano, BW Segelke, EA Stura, PA Peterson, IA Wilson
Science 277 (5324), 339-345, 1997
7871997
Two divalent metal ions in the active site of a new crystal form of human apurinic/apyrimidinic endonuclease, ape1: implications for the catalytic mechanism1
PT Beernink, BW Segelke, MZ Hadi, JP Erzberger, DM Wilson Iii, B Rupp
Journal of molecular biology 307 (4), 1023-1034, 2001
2242001
Fixed-target protein serial microcrystallography with an x-ray free electron laser
MS Hunter, B Segelke, M Messerschmidt, GJ Williams, NA Zatsepin, ...
Scientific reports 4, 6026, 2014
2132014
The CD1 family of lipid antigen-presenting molecules
SA Porcelli, BW Segelke, M Sugita, IA Wilson, MB Brenner
Immunology today 19 (8), 362-368, 1998
2061998
Cell-free co-expression of functional membrane proteins and apolipoprotein, forming soluble nanolipoprotein particles
JA Cappuccio, CD Blanchette, TA Sulchek, ES Arroyo, JM Kralj, AK Hinz, ...
Molecular & Cellular Proteomics 7 (11), 2246-2253, 2008
1472008
Different apolipoproteins impact nanolipoprotein particle formation
BA Chromy, E Arroyo, CD Blanchette, G Bench, H Benner, JA Cappuccio, ...
Journal of the American Chemical Society 129 (46), 14348-14354, 2007
1232007
Interaction of the N-terminal domain of apolipoprotein E4 with heparin
J Dong, CA Peters-Libeu, KH Weisgraber, BW Segelke, B Rupp, I Capila, ...
Biochemistry 40 (9), 2826-2834, 2001
1212001
Crystal structure of the Mycobacterium tuberculosis dUTPase: insights into the catalytic mechanism
S Chan, B Segelke, T Lekin, H Krupka, US Cho, M Kim, M So, CY Kim, ...
Journal of molecular biology 341 (2), 503-517, 2004
1172004
Crystal structure of Clostridium botulinum neurotoxin protease in a product-bound state: Evidence for noncanonical zinc protease activity
B Segelke, M Knapp, S Kadkhodayan, R Balhorn, B Rupp
Proceedings of the National Academy of Sciences of the United States of …, 2004
1172004
Efficiency analysis of sampling protocols used in protein crystallization screening
BW Segelke
Journal of crystal growth 232 (1-4), 553-562, 2001
1072001
Crystal Structure of AhpE from Mycobacterium tuberculosis, a 1-Cys peroxiredoxin
S Li, NA Peterson, MY Kim, CY Kim, LW Hung, M Yu, T Lekin, ...
Journal of molecular biology 346 (4), 1035-1046, 2005
962005
Femtosecond X-ray diffraction from two-dimensional protein crystals
M Frank, DB Carlson, MS Hunter, GJ Williams, M Messerschmidt, ...
IUCrJ 1 (2), 95-100, 2014
942014
The TB structural genomics consortium crystallization facility: towards automation from protein to electron density
B Rupp, BW Segelke, HI Krupka, T Lekin, J Schäfer, A Zemla, D Toppani, ...
Acta Crystallographica Section D: Biological Crystallography 58 (10), 1514-1518, 2002
922002
Structures of two novel crystal forms of Naja naja naja phospholipase A2 lacking Ca2+ reveal trimeric packing1
BW Segelke, D Nguyen, R Chee, NH Xuong, EA Dennis
Journal of molecular biology 279 (1), 223-232, 1998
811998
Quantifying size distributions of nanolipoprotein particles with single-particle analysis and molecular dynamic simulations
CD Blanchette, R Law, WH Benner, JB Pesavento, JA Cappuccio, ...
Journal of lipid research 49 (7), 1420-1430, 2008
722008
Amino acid and structural variability of Yersinia pestis LcrV protein
AP Anisimov, SV Dentovskaya, EA Panfertsev, ES Tat’yana, PK Kopylov, ...
Infection, Genetics and Evolution 10 (1), 137-145, 2010
692010
The high-speed Hydra-Plus-One system for automated high-throughput protein crystallography
HI Krupka, B Rupp, BW Segelke, T Lekin, D Wright, HC Wu, P Todd, ...
Acta Crystallographica Section D: Biological Crystallography 58 (10), 1523-1526, 2002
672002
Immobilization of His-tagged proteins on nickel-chelating nanolipoprotein particles
NO Fischer, CD Blanchette, BA Chromy, EA Kuhn, BW Segelke, M Corzett, ...
Bioconjugate chemistry 20 (3), 460-465, 2009
642009
Effective electron-density map improvement and structure validation on a Linux multi-CPU web cluster: The TB Structural Genomics Consortium Bias Removal Web Service
V Reddy, S Swanson, B Segelke, KA Kantardjieff, JC Sacchettini, B Rupp
Acta Crystallographica Section D: Biological Crystallography 59 (12), 2200-2210, 2003
622003
High-throughput, fluorescence-based screening for soluble protein expression
MA Coleman, VH Lao, BW Segelke, PT Beernink
Journal of proteome research 3 (5), 1024-1032, 2004
592004
El sistema no puede realizar la operación en estos momentos. Inténtalo de nuevo más tarde.
Artículos 1–20