Stephan Ginell
Stephan Ginell
Hauptman-Woodward Medical Research Inst
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From molecular to macroscopic via the rational design of a self-assembled 3D DNA crystal
J Zheng, JJ Birktoft, Y Chen, T Wang, R Sha, PE Constantinou, SL Ginell, ...
Nature 461 (7260), 74-77, 2009
The productive conformation of arachidonic acid bound to prostaglandin synthase
MG Malkowski, SL Ginell, WL Smith, RM Garavito
Science 289 (5486), 1933-1937, 2000
The Structural Biology Center 19ID undulator beamline: facility specifications and protein crystallographic results
G Rosenbaum, RW Alkire, G Evans, FJ Rotella, K Lazarski, RG Zhang, ...
Journal of synchrotron radiation 13 (1), 30-45, 2006
Non-classical transpeptidases yield insight into new antibacterials
P Kumar, A Kaushik, EP Lloyd, SG Li, R Mattoo, NC Ammerman, DT Bell, ...
Nature chemical biology 13 (1), 54-61, 2017
Quantum model of catalysis based on a mobile proton revealed by subatomic x-ray and neutron diffraction studies of h-aldose reductase
MP Blakeley, F Ruiz, R Cachau, I Hazemann, F Meilleur, A Mitschler, ...
Proceedings of the National Academy of Sciences 105 (6), 1844-1848, 2008
Structure of porcine aldehyde reductase holoenzyme
O El-Kabbani, K Judge, SL Ginell, DAA Myles, LJ DeLucas, TG Flynn
nature structural biology 2 (8), 687-692, 1995
Mycobacterium abscessus l,d-Transpeptidases Are Susceptible to Inactivation by Carbapenems and Cephalosporins but Not Penicillins
P Kumar, V Chauhan, JRA Silva, J Lameira, FB d'Andrea, SG Li, SL Ginell, ...
Antimicrobial agents and chemotherapy 61 (10), 10.1128/aac. 00866-17, 2017
The many faces of radiation-induced changes
D Borek, SL Ginell, M Cymborowski, W Minor, Z Otwinowski
Journal of synchrotron radiation 14 (1), 24-33, 2007
Mutational and x-ray crystallographic analysis of the interaction of dihomo-γ-linolenic acid with prostaglandin endoperoxide H synthases
ED Thuresson, MG Malkowski, KM Lakkides, CJ Rieke, AM Mulichak, ...
Journal of Biological Chemistry 276 (13), 10358-10365, 2001
Crystal and molecular structure of a DNA fragment: d (CGTGAATTCACG)
N Narayana, SL Ginell, IM Russu, HM Berman
Biochemistry 30 (18), 4449-4455, 1991
Crystal and molecular structure of a DNA duplex containing the carcinogenic lesion O6-methylguanine
SL Ginell, S Kuzmich, RA Jones, HM Berman
Biochemistry 29 (46), 10461-10465, 1990
Exploring the mechanism of β-lactam ring protonation in the class A β-lactamase acylation mechanism using neutron and X-ray crystallography
VG Vandavasi, KL Weiss, JB Cooper, PT Erskine, SJ Tomanicek, ...
Journal of medicinal chemistry 59 (1), 474-479, 2016
Crystal Structure of Human Complement Protein C8γ at 1.2 Å Resolution Reveals a Lipocalin Fold and a Distinct Ligand Binding Site,
E Ortlund, CL Parker, SF Schreck, S Ginell, W Minor, JM Sodetz, ...
Biochemistry 41 (22), 7030-7037, 2002
Conformation of N4-acetylcytidine, a modified nucleoside of tRNA, and stereochemistry of codon-anticodon interaction
R Parthasarathy, SL Ginell, NC De, GB Chheda
Biochemical and Biophysical Research Communications 83 (2), 657-663, 1978
Active-site protonation states in an acyl-enzyme intermediate of a class A β-lactamase with a monobactam substrate
VG Vandavasi, PS Langan, KL Weiss, JM Parks, JB Cooper, SL Ginell, ...
Antimicrobial agents and chemotherapy 61 (1), 10.1128/aac. 01636-16, 2017
Crystal and molecular structure of a DNA fragment containing a 2-aminoadenine modification: the relationship between conformation, packing, and hydration in Z-DNA hexamers
B Schneider, SL Ginell, R Jones, B Gaffney, HM Berman
Biochemistry 31 (40), 9622-9628, 1992
The absence of tertiary interactions in a self‐assembled DNA crystal structure
N Nguyen, JJ Birktoft, R Sha, T Wang, J Zheng, PE Constantinou, ...
Journal of Molecular Recognition 25 (4), 234-237, 2012
The crystal and molecular structure of the anticancer drug actinomycin D—some explanations for its unusual properties
S Ginell, L Lessinger, HM Berman
Biopolymers: Original Research on Biomolecules 27 (5), 843-864, 1988
Substrate binding induces conformational changes in a class A β-lactamase that prime it for catalysis
PS Langan, VG Vandavasi, CJ Cooper, KL Weiss, SL Ginell, JM Parks, ...
Acs Catalysis 8 (3), 2428-2437, 2018
Towards protein-crystal centering using second-harmonic generation (SHG) microscopy
DJ Kissick, CM Dettmar, M Becker, AM Mulichak, V Cherezov, SL Ginell, ...
Acta Crystallographica Section D: Biological Crystallography 69 (5), 843-851, 2013
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