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David C Gershlick
David C Gershlick
Cambridge Institute for Medical Research, The University of Cambridge
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Structural mechanism for cargo recognition by the retromer complex
M Lucas, DC Gershlick, A Vidaurrazaga, AL Rojas, JS Bonifacino, ...
Cell 167 (6), 1623-1635. e14, 2016
2182016
Direct trafficking pathways from the Golgi apparatus to the plasma membrane
D Stalder, DC Gershlick
Seminars in cell & developmental biology 107, 112-125, 2020
942020
A recycling-defective vacuolar sorting receptor reveals an intermediate compartment situated between prevacuoles and vacuoles in tobacco
O Foresti, DC Gershlick, F Bottanelli, E Hummel, C Hawes, J Denecke
The Plant Cell 22 (12), 3992-4008, 2010
862010
Segregation in the Golgi complex precedes export of endolysosomal proteins in distinct transport carriers
Y Chen, DC Gershlick, SY Park, JS Bonifacino
Journal of Cell Biology 216 (12), 4141-4151, 2017
802017
Mechanisms and concepts paving the way towards a complete transport cycle of plant vacuolar sorting receptors
C De Marcos Lousa, DC Gershlick, J Denecke
The Plant Cell 24 (5), 1714-1732, 2012
802012
Evidence for sequential action of rab 5 and rab 7 GTP ases in prevacuolar organelle partitioning
F Bottanelli, DC Gershlick, J Denecke
Traffic 13 (2), 338-354, 2012
772012
Novel role for the midbody in primary ciliogenesis by polarized epithelial cells
M Bernabé-Rubio, G Andrés, J Casares-Arias, J Fernández-Barrera, ...
Journal of Cell Biology 214 (3), 259-273, 2016
762016
Immunoprecipitation
JS Bonifacino, DC Gershlick, EC Dell'Angelica
Current Protocols in Cell Biology, 2016
712016
The Parkinson’s disease protein LRRK2 interacts with the GARP complex to promote retrograde transport to the trans-Golgi network
A Beilina, L Bonet-Ponce, R Kumaran, JJ Kordich, M Ishida, A Mamais, ...
Cell reports 31 (5), 2020
592020
Mutations in LRRK2 linked to Parkinson disease sequester Rab8a to damaged lysosomes and regulate transferrin-mediated iron uptake in microglia
A Mamais, JH Kluss, L Bonet-Ponce, N Landeck, RG Langston, N Smith, ...
PLoS biology 19 (12), e3001480, 2021
512021
Molecular mechanism for the subversion of the retromer coat by the Legionella effector RidL
M Romano-Moreno, AL Rojas, CD Williamson, DC Gershlick, M Lucas, ...
Proceedings of the National Academy of Sciences 114 (52), E11151-E11160, 2017
472017
A neurodevelopmental disorder caused by mutations in the VPS51 subunit of the GARP and EARP complexes
DC Gershlick, M Ishida, JR Jones, A Bellomo, JS Bonifacino, DB Everman
Human molecular genetics 28 (9), 1548-1560, 2019
462019
Golgi-dependent transport of vacuolar sorting receptors is regulated by COPII, AP1, and AP4 protein complexes in tobacco
DC Gershlick, CM Lousa, O Foresti, AJ Lee, EA Pereira, LLP daSilva, ...
The Plant Cell 26 (3), 1308-1329, 2014
412014
SNX19 restricts endolysosome motility through contacts with the endoplasmic reticulum
A Saric, SA Freeman, CD Williamson, M Jarnik, CM Guardia, ...
Nature communications 12 (1), 4552, 2021
382021
TSSC1 is novel component of the endosomal retrieval machinery
DC Gershlick, C Schindler, Y Chen, JS Bonifacino
Molecular biology of the cell 27 (18), 2867-2878, 2016
282016
Liquid–liquid phase separation facilitates the biogenesis of secretory storage granules
A Parchure, M Tian, D Stalder, CK Boyer, SC Bearrows, KE Rohli, ...
Journal of Cell Biology 221 (12), e202206132, 2022
222022
Formation of tubulovesicular carriers from endosomes and their fusion to the trans-Golgi network
A Hierro, DC Gershlick, AL Rojas, JS Bonifacino
International review of cell and molecular biology 318, 159-202, 2015
192015
Endosomal trafficking: retromer and retriever are relatives in recycling
DC Gershlick, M Lucas
Current Biology 27 (22), R1233-R1236, 2017
142017
Mutations in Auxilin cause parkinsonism via impaired clathrin-mediated trafficking at the Golgi apparatus and synapse
DA Roosen, N Landeck, M Conti, N Smith, S Saez-Atienzar, J Ding, ...
Biorxiv, 830802, 2019
132019
The exocyst complex is an essential component of the mammalian constitutive secretory pathway
C Pereira, D Stalder, GSF Anderson, AS Shun-Shion, J Houghton, ...
Journal of Cell Biology 222 (5), e202205137, 2023
112023
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