| Digital signaling and hysteresis characterize ras activation in lymphoid cells J Das, M Ho, J Zikherman, C Govern, M Yang, A Weiss, AK Chakraborty, ... Cell 136 (2), 337-351, 2009 | 476 | 2009 |
| Role of nanoscale antigen organization on B-cell activation probed using DNA origami R Veneziano, TJ Moyer, MB Stone, EC Wamhoff, BJ Read, S Mukherjee, ... Nature nanotechnology 15 (8), 716-723, 2020 | 291 | 2020 |
| The balance between T cell receptor signaling and degradation at the center of the immunological synapse is determined by antigen quality S Čemerski, J Das, E Giurisato, MA Markiewicz, PM Allen, ... Immunity 29 (3), 414-422, 2008 | 167 | 2008 |
| Purely stochastic binary decisions in cell signaling models without underlying deterministic bistabilities MN Artyomov, J Das, M Kardar, AK Chakraborty Proceedings of the National Academy of Sciences 104 (48), 18958-18963, 2007 | 121 | 2007 |
| The stimulatory potency of T cell antigens is influenced by the formation of the immunological synapse S Čemerski, J Das, J Locasale, P Arnold, E Giurisato, MA Markiewicz, ... Immunity 26 (3), 345-355, 2007 | 118 | 2007 |
| Monovalent and multivalent ligation of the B cell receptor exhibit differential dependence upon Syk and Src family kinases S Mukherjee, J Zhu, J Zikherman, R Parameswaran, TA Kadlecek, ... Science signaling 6 (256), ra1-ra1, 2013 | 84 | 2013 |
| Origin of the sharp boundary that discriminates positive and negative selection of thymocytes A Prasad, J Zikherman, J Das, JP Roose, A Weiss, AK Chakraborty Proceedings of the National Academy of Sciences 106 (2), 528-533, 2009 | 75 | 2009 |
| Decreased diacylglycerol metabolism enhances ERK activation and augments CD8+ T cell functional responses MJ Riese, J Grewal, J Das, T Zou, V Patil, AK Chakraborty, GA Koretzky Journal of biological chemistry 286 (7), 5254-5265, 2011 | 74 | 2011 |
| Pairing computation with experimentation: a powerful coupling for understanding T cell signalling AK Chakraborty, J Das Nature Reviews Immunology 10 (1), 59-71, 2010 | 68 | 2010 |
| The ζ isoform of diacylglycerol kinase plays a predominant role in regulatory T cell development and TCR-mediated ras signaling RP Joshi, AM Schmidt, J Das, D Pytel, MJ Riese, M Lester, JA Diehl, ... Science signaling 6 (303), ra102-ra102, 2013 | 63 | 2013 |
| Sensitivity of T cells to antigen and antagonism emerges from differential regulation of the same molecular signaling module DC Wylie, J Das, AK Chakraborty Proceedings of the National Academy of Sciences 104 (13), 5533-5538, 2007 | 63 | 2007 |
| NK cells: tuned by peptide? J Das, SI Khakoo Immunological reviews 267 (1), 214-227, 2015 | 46 | 2015 |
| A dendronized polymer is a single-molecule glass J Das, M Yoshida, ZM Fresco, TL Choi, JMJ Fréchet, AK Chakraborty The Journal of Physical Chemistry B 109 (14), 6535-6543, 2005 | 40 | 2005 |
| Positive feedback regulation results in spatial clustering and fast spreading of active signaling molecules on a cell membrane J Das, M Kardar, AK Chakraborty The Journal of Chemical Physics 130 (24), 2009 | 39 | 2009 |
| Effect of cross-linking on the structure and thermodynamics of lamellar block copolymers ED Gomez, J Das, AK Chakraborty, JA Pople, NP Balsara Macromolecules 39 (14), 4848-4859, 2006 | 38 | 2006 |
| Extracellular DNA and Type IV Pilus Expression Regulate the Structure and Kinetics of Biofilm Formation by Nontypeable Haemophilus influenzae J Das, E Mokrzan, V Lakhani, L Rosas, JA Jurcisek, WC Ray, LO Bakaletz MBio 8 (6), 10.1128/mbio. 01466-17, 2017 | 35 | 2017 |
| Activation or tolerance of natural killer cells is modulated by ligand quality in a nonmonotonic manner J Das Biophysical journal 99 (7), 2028-2037, 2010 | 34 | 2010 |
| Peptide selectivity discriminates NK cells from KIR2DL2‐and KIR2DL3‐positive individuals S Cassidy, S Mukherjee, TM Myint, B Mbiribindi, H North, J Traherne, ... European journal of immunology 45 (2), 492-500, 2015 | 30 | 2015 |
| Molecular origin and functional consequences of digital signaling and hysteresis during Ras activation in lymphocytes AK Chakraborty, J Das, J Zikherman, M Yang, CC Govern, M Ho, A Weiss, ... Science signaling 2 (66), pt2-pt2, 2009 | 30 | 2009 |
| In silico modeling identifies CD45 as a regulator of IL-2 synergy in the NKG2D-mediated activation of immature human NK cells S Mukherjee, H Jensen, W Stewart, D Stewart, WC Ray, SY Chen, ... Science signaling 10 (485), eaai9062, 2017 | 28 | 2017 |
Julie ZikhermanUCSF Medical CenterVerified email at ucsf.edu
