Sequencing of neuroblastoma identifies chromothripsis and defects in neuritogenesis genes JJ Molenaar, J Koster, DA Zwijnenburg, P Van Sluis, LJ Valentijn, ... Nature 483 (7391), 589-593, 2012 | 938 | 2012 |
RNA-Seq of tumor-educated platelets enables blood-based pan-cancer, multiclass, and molecular pathway cancer diagnostics MG Best, N Sol, I Kooi, J Tannous, BA Westerman, F Rustenburg, ... Cancer cell 28 (5), 666-676, 2015 | 829 | 2015 |
Neuroblastoma is composed of two super-enhancer-associated differentiation states T Van Groningen, J Koster, LJ Valentijn, DA Zwijnenburg, N Akogul, ... Nature genetics 49 (8), 1261-1266, 2017 | 428 | 2017 |
Longitudinal molecular trajectories of diffuse glioma in adults FP Barthel, KC Johnson, FS Varn, AD Moskalik, G Tanner, E Kocakavuk, ... Nature 576 (7785), 112-120, 2019 | 390 | 2019 |
Glioma progression is shaped by genetic evolution and microenvironment interactions FS Varn, KC Johnson, J Martinek, JT Huse, MLP Nasrallah, P Wesseling, ... Cell 185 (12), 2184-2199. e16, 2022 | 188 | 2022 |
ZNF423 is critically required for retinoic acid-induced differentiation and is a marker of neuroblastoma outcome S Huang, J Laoukili, MT Epping, J Koster, M Hölzel, BA Westerman, ... Cancer cell 15 (4), 328-340, 2009 | 154 | 2009 |
The parent-of-origin effect of 10q22 in pre-eclamptic females coincides with two regions clustered for genes with down-regulated expression in androgenetic placentas CBM Oudejans, J Mulders, AMA Lachmeijer, M van Dijk, AAM Könst, ... Molecular human reproduction 10 (8), 589-598, 2004 | 140 | 2004 |
Akt-mediated phosphorylation of Bmi1 modulates its oncogenic potential, E3 ligase activity, and DNA damage repair activity in mouse prostate cancer K Nacerddine, JB Beaudry, V Ginjala, B Westerman, F Mattiroli, JY Song, ... The Journal of clinical investigation 122 (5), 1920-1932, 2012 | 139 | 2012 |
The landscape of atypical and eukaryotic protein kinases GK Kanev, C de Graaf, IJP de Esch, R Leurs, T Würdinger, BA Westerman, ... Trends in pharmacological sciences 40 (11), 818-832, 2019 | 114 | 2019 |
Detection of chromosome 21-encoded mRNA of placental origin in maternal plasma CBM Oudejans, ATJJ Go, A Visser, MAM Mulders, BA Westerman, ... Clinical chemistry 49 (9), 1445-1449, 2003 | 108 | 2003 |
KLIFS: an overhaul after the first 5 years of supporting kinase research GK Kanev, C de Graaf, BA Westerman, IJP de Esch, AJ Kooistra Nucleic acids research 49 (D1), D562-D569, 2021 | 96 | 2021 |
p120-catenin-dependent collective brain infiltration by glioma cell networks PG Gritsenko, N Atlasy, CEJ Dieteren, AC Navis, JH Venhuizen, ... Nature cell biology 22 (1), 97-107, 2020 | 95 | 2020 |
Circulating trophoblast in maternal blood CBM Oudejans, ML Tjoa, BA Westerman, MAM Mulders, IJ Van Wijk, ... Prenatal Diagnosis: Published in Affiliation With the International Society …, 2003 | 88 | 2003 |
Glycosylated extracellular vesicles released by glioblastoma cells are decorated by CCL18 allowing for cellular uptake via chemokine receptor CCR8 J Berenguer, T Lagerweij, XW Zhao, S Dusoswa, P Van Der Stoop, ... Journal of extracellular vesicles 7 (1), 1446660, 2018 | 81 | 2018 |
Bmi1 is required for Hedgehog pathway-driven medulloblastoma expansion LE Michael, BA Westerman, AN Ermilov, A Wang, J Ferris, J Liu, M Blom, ... Neoplasia 10 (12), 1343-IN8, 2008 | 73 | 2008 |
A cancer drug atlas enables synergistic targeting of independent drug vulnerabilities RS Narayan, P Molenaar, J Teng, FMG Cornelissen, I Roelofs, ... Nature communications 11 (1), 2935, 2020 | 71 | 2020 |
The allosteric AKT inhibitor MK2206 shows a synergistic interaction with chemotherapy and radiotherapy in glioblastoma spheroid cultures RS Narayan, CA Fedrigo, E Brands, R Dik, LJA Stalpers, BG Baumert, ... BMC cancer 17, 1-8, 2017 | 68 | 2017 |
Allelic IGF2R repression does not correlate with expression of antisense RNA in human extraembryonic tissues CBM Oudejans, B Westerman, D Wouters, S Gooyer, PAJ Leegwater, ... Genomics 73 (3), 331-337, 2001 | 65 | 2001 |
Crowdsourced mapping of unexplored target space of kinase inhibitors A Cichońska, B Ravikumar, RJ Allaway, F Wan, S Park, O Isayev, S Li, ... Nature communications 12 (1), 3307, 2021 | 62 | 2021 |
Quantitative Reverse Transcription-Polymerase Chain Reaction Measurement of HASH1 (ASCL1), a Marker for Small Cell Lung Carcinomas with … BA Westerman, S Neijenhuis, A Poutsma, RDM Steenbergen, RHJ Breuer, ... Clinical cancer research 8 (4), 1082-1086, 2002 | 54 | 2002 |