| Estrogen receptors alpha (ERα) and beta (ERβ): subtype-selective ligands and clinical potential I Paterni, C Granchi, JA Katzenellenbogen, F Minutolo Steroids 90, 13-29, 2014 | 742 | 2014 |
| Past, present, and future of Bcr-Abl inhibitors: from chemical development to clinical efficacy F Rossari, F Minutolo, E Orciuolo Journal of hematology & oncology 11, 1-14, 2018 | 330 | 2018 |
| Inhibitors of lactate dehydrogenase isoforms and their therapeutic potentials C Granchi, S Bertini, M Macchia, F Minutolo Current medicinal chemistry 17 (7), 672-697, 2010 | 266 | 2010 |
| Discovery of N-Hydroxyindole-Based Inhibitors of Human Lactate Dehydrogenase Isoform A (LDH-A) as Starvation Agents against Cancer Cells C Granchi, S Roy, C Giacomelli, M Macchia, T Tuccinardi, A Martinelli, ... Journal of medicinal chemistry 54 (6), 1599-1612, 2011 | 256 | 2011 |
| Heterogeneous asymmetric epoxidation of unfunctionalized olefins catalyzed by polymer-bound (salen) manganese complexes F Minutolo, D Pini, A Petri, P Salvadori Tetrahedron: Asymmetry 7 (8), 2293-2302, 1996 | 225 | 1996 |
| Increased lactate secretion by cancer cells sustains non-cell-autonomous adaptive resistance to MET and EGFR targeted therapies M Apicella, E Giannoni, S Fiore, KJ Ferrari, D Fernández-Pérez, C Isella, ... Cell metabolism 28 (6), 848-865. e6, 2018 | 218 | 2018 |
| Anticancer agents that counteract tumor glycolysis C Granchi, F Minutolo ChemMedChem 7 (8), 1318-1350, 2012 | 208 | 2012 |
| Synergistic interaction of novel lactate dehydrogenase inhibitors with gemcitabine against pancreatic cancer cells in hypoxia M Maftouh, A Avan, R Sciarrillo, C Granchi, LG Leon, R Rani, N Funel, ... British journal of cancer 110 (1), 172-182, 2014 | 174 | 2014 |
| Polymer-bound chiral (salen) Mn (III) complex as heterogeneous catalyst in rapid and clean enantioselective epoxidation of unfunctionalised olefins F Minutolo, D Pini, P Salvadori Tetrahedron Letters 37 (19), 3375-3378, 1996 | 173 | 1996 |
| Estrogen receptor β ligands: recent advances and biomedical applications F Minutolo, M Macchia, BS Katzenellenbogen, JA Katzenellenbogen Medicinal research reviews 31 (3), 364-442, 2011 | 170 | 2011 |
| Identification of LDH-A as a therapeutic target for cancer cell killing via (i) p53/NAD (H)-dependent and (ii) p53-independent pathways SJ Allison, JRP Knight, C Granchi, R Rani, F Minutolo, J Milner, ... Oncogenesis 3 (5), e102-e102, 2014 | 136 | 2014 |
| An update on therapeutic opportunities offered by cancer glycolytic metabolism C Granchi, D Fancelli, F Minutolo Bioorganic & medicinal chemistry letters 24 (21), 4915-4925, 2014 | 119 | 2014 |
| New N-arylsulfonyl-N-alkoxyaminoacetohydroxamic acids as selective inhibitors of gelatinase A (MMP-2) A Rossello, E Nuti, E Orlandini, P Carelli, S Rapposelli, M Macchia, ... Bioorganic & medicinal chemistry 12 (9), 2441-2450, 2004 | 102 | 2004 |
| Heparin in COVID-19 patients is associated with reduced in-hospital mortality: the multicenter Italian CORIST study A Di Castelnuovo, S Costanzo, A Antinori, N Berselli, L Blandi, ... Thrombosis and haemostasis 121 (08), 1054-1065, 2021 | 100 | 2021 |
| Synthesis of a resveratrol analogue with high ceramide-mediated proapoptotic activity on human breast cancer cells F Minutolo, G Sala, A Bagnacani, S Bertini, I Carboni, G Placanica, ... Journal of medicinal chemistry 48 (22), 6783-6786, 2005 | 99 | 2005 |
| Small-molecule inhibitors of human LDH5 C Granchi, I Paterni, R Rani, F Minutolo Future medicinal chemistry 5 (16), 1967-1991, 2013 | 98 | 2013 |
| Use of hydroxychloroquine in hospitalised COVID-19 patients is associated with reduced mortality: Findings from the observational multicentre Italian CORIST study A Di Castelnuovo, S Costanzo, A Antinori, N Berselli, L Blandi, R Bruno, ... European Journal of Internal Medicine 82, 38-47, 2020 | 93 | 2020 |
| Phospho-Akt overexpression is prognostic and can be used to tailor the synergistic interaction of Akt inhibitors with gemcitabine in pancreatic cancer D Massihnia, A Avan, N Funel, M Maftouh, A Van Krieken, C Granchi, ... Journal of Hematology & Oncology 10, 1-17, 2017 | 89 | 2017 |
| Lactate dehydrogenase-A inhibition induces human glioblastoma multiforme stem cell differentiation and death S Daniele, C Giacomelli, E Zappelli, C Granchi, ML Trincavelli, F Minutolo, ... Scientific reports 5 (1), 15556, 2015 | 85 | 2015 |
| The dichotomous role of the glycolytic metabolism pathway in cancer metastasis: interplay with the complex tumor microenvironment and novel therapeutic strategies B El Hassouni, C Granchi, A Vallés-Martí, IGP Supadmanaba, G Bononi, ... Seminars in cancer biology 60, 238-248, 2020 | 84 | 2020 |
