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Ibolya Leveles
Ibolya Leveles
BME ABÉT
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Aromatic stacking between nucleobase and enzyme promotes phosphate ester hydrolysis in dUTPase
I Pecsi, I Leveles, V Harmat, BG Vertessy, J Toth
Nucleic acids research 38 (20), 7179-7186, 2010
752010
Highly potent dUTPase inhibition by a bacterial repressor protein reveals a novel mechanism for gene expression control
JE Szabo, V Németh, V Papp-Kádár, K Nyíri, I Leveles, AA Bendes, ...
Nucleic acids research 42 (19), 11912-11920, 2014
592014
Regulation of the equilibrium between closed and open conformations of annexin A2 by N-terminal phosphorylation and S100A4-binding
P Ecsédi, B Kiss, G Gógl, L Radnai, L Buday, K Koprivanacz, K Liliom, ...
Structure 25 (8), 1195-1207. e5, 2017
502017
Preventive DNA repair by sanitizing the cellular (deoxy) nucleoside triphosphate pool
GN Nagy, I Leveles, BG Vértessy
The FEBS journal 281 (18), 4207-4223, 2014
502014
Structural characterization of arginine fingers: identification of an arginine finger for the pyrophosphatase dUTPases
GN Nagy, R Suardíaz, A Lopata, O Ozohanics, K Vékey, BR Brooks, ...
Journal of the American Chemical Society 138 (45), 15035-15045, 2016
442016
Structure and enzymatic mechanism of a moonlighting dUTPase
I Leveles, V Németh, JE Szabó, V Harmat, K Nyíri, ÁÁ Bendes, ...
Acta Crystallographica Section D: Biological Crystallography 69 (12), 2298-2308, 2013
342013
A novel fruitfly protein under developmental control degrades uracil-DNA
A Békési, M Pukáncsik, V Muha, I Zagyva, I Leveles, E Hunyadi-Gulyás, ...
Biochemical and biophysical research communications 355 (3), 643-648, 2007
322007
Direct contacts between conserved motifs of different subunits provide major contribution to active site organization in human and mycobacterial dUTPases
E Takács, G Nagy, I Leveles, V Harmat, A Lopata, J Tóth, BG Vértessy
FEBS letters 584 (14), 3047-3054, 2010
302010
The electrical conductivity of living tissue: a parameter in the bioelectrical inverse problem
MJ Peters, JG Stinstra, I Leveles
Modeling and Imaging of Bioelectrical Activity: Principles and Applications …, 2005
222005
The First Enantioselective Total Synthesis of (−)-trans-Dihydronarciclasine
G Varró, L Hegedűs, A Simon, A Balogh, A Grün, I Leveles, ...
Journal of Natural Products 80 (6), 1909-1917, 2017
212017
Substrate tunnel engineering aided by X-ray crystallography and functional dynamics swaps the function of MIO-enzymes
Z Bata, Z Molnar, E Madaras, B Molnar, E Santa-Bell, A Varga, I Leveles, ...
Acs Catalysis 11 (8), 4538-4549, 2021
202021
Molecular dynamics of the cryo-EM CFTR structure
H Tordai, I Leveles, T Hegedűs
Biochemical and biophysical research communications 491 (4), 986-993, 2017
202017
Structural insights into the tyrosine phosphorylation–mediated inhibition of SH3 domain–ligand interactions
B Merő, L Radnai, G Gógl, O Tőke, I Leveles, K Koprivanacz, B Szeder, ...
Journal of Biological Chemistry 294 (12), 4608-4620, 2019
162019
A hidden active site in the potential drug target mycobacterium tuberculosis dUTPase is accessible through small amplitude protein conformational changes
A Lopata, I Leveles, ÁÁ Bendes, B Viskolcz, BG Vértessy, B Jójárt, J Tóth
Journal of Biological Chemistry 291 (51), 26320-26331, 2016
152016
Beyond chelation: EDTA tightly binds taq DNA polymerase, MutT and dUTPase and directly inhibits dNTPase activity
A Lopata, B Jójárt, ÉV Surányi, E Takács, L Bezúr, I Leveles, ÁÁ Bendes, ...
Biomolecules 9 (10), 621, 2019
132019
Crystallization and preliminary crystallographic analysis of dUTPase from the φ11 helper phage of Staphylococcus aureus
I Leveles, G Róna, I Zagyva, Á Bendes, V Harmat, BG Vértessy
Acta Crystallographica Section F: Structural Biology and Crystallization …, 2011
122011
Structural characterization of a complex derived from lead (II) perchlorate and acridono-18-crown-6 ether
T Németh, Á Golcs, I Leveles, T Tóth, BG Vértessy, P Huszthy
Structural Chemistry 26, 1467-1471, 2015
112015
Origin of problems related to Staudinger reduction in carbopeptoid syntheses
B Csordás, A Nagy, V Harmat, V Zsoldos-Mády, I Leveles, I Pintér, ...
Amino Acids 48, 2619-2633, 2016
102016
Structural characterization of the crystalline diastereomeric complexes of enantiopure dimethylacridino-18-crown-6 ether and the enantiomers of 1-(1-naphthyl) ethylamine …
T Tóth, T Németh, I Leveles, BG Vértessy, P Huszthy
Structural Chemistry 28, 289-296, 2017
82017
Association of RNA with the uracil‐DNA‐degrading factor has major conformational effects and is potentially involved in protein folding
A Bekesi, M Pukancsik, P Haasz, L Felfoldi, I Leveles, V Muha, ...
The FEBS Journal 278 (2), 295-315, 2011
82011
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Artículos 1–20