| Dioxygen activation and methane hydroxylation by soluble methane monooxygenase: a tale of two irons and three proteins M Merkx, DA Kopp, MH Sazinsky, JL Blazyk, J Müller, SJ Lippard Angewandte Chemie International Edition 40 (15), 2782-2807, 2001 | 810 | 2001 |
| Genetically encoded FRET sensors to monitor intracellular Zn2+ homeostasis JL Vinkenborg, TJ Nicolson, EA Bellomo, MS Koay, GA Rutter, M Merkx Nature methods 6 (10), 737-740, 2009 | 439 | 2009 |
| Human copper transporter 2 is localized in late endosomes and lysosomes and facilitates cellular copper uptake PVE Van den Berghe, DE Folmer, HEM Malingré, E Van Beurden, ... Biochemical Journal 407 (1), 49-59, 2007 | 225 | 2007 |
| Quantitative understanding of the energy transfer between fluorescent proteins connected via flexible peptide linkers TH Evers, EMWM van Dongen, AC Faesen, EW Meijer, M Merkx Biochemistry 45 (44), 13183-13192, 2006 | 224 | 2006 |
| Fluorescently labeled collagen binding proteins allow specific visualization of collagen in tissues and live cell culture KN Krahn, CVC Bouten, S van Tuijl, MAMJ van Zandvoort, M Merkx Analytical biochemistry 350 (2), 177-185, 2006 | 181 | 2006 |
| Inhibition of human copper trafficking by a small molecule significantly attenuates cancer cell proliferation J Wang, C Luo, C Shan, Q You, J Lu, S Elf, Y Zhou, Y Wen, JL Vinkenborg, ... Nature chemistry 7 (12), 968-979, 2015 | 165 | 2015 |
| Branched KLVFF tetramers strongly potentiate inhibition of β‐Amyloid aggregation SM Chafekar, H Malda, M Merkx, EW Meijer, D Viertl, HA Lashuel, F Baas, ... ChemBioChem 8 (15), 1857-1864, 2007 | 159 | 2007 |
| Tuning the flexibility of glycine-serine linkers to allow rational design of multidomain proteins M Van Rosmalen, M Krom, M Merkx Biochemistry 56 (50), 6565-6574, 2017 | 128 | 2017 |
| Supramolecular Control of Enzyme Activity through Cucurbit [8] uril‐Mediated Dimerization DT Dang, HD Nguyen, M Merkx, L Brunsveld Angewandte Chemie International Edition 10 (52), 2915-2919, 2013 | 124 | 2013 |
| Multivalent peptide and protein dendrimers using native chemical ligation I van Baal, H Malda, SA Synowsky, JLJ van Dongen, TM Hackeng, ... Angewandte Chemie 117 (32), 5180-5185, 2005 | 118 | 2005 |
| Paper‐based antibody detection devices using bioluminescent BRET‐switching sensor proteins K Tenda, B van Gerven, R Arts, Y Hiruta, M Merkx, D Citterio Angewandte Chemie International Edition 57 (47), 15369-15373, 2018 | 116 | 2018 |
| Detection of antibodies in blood plasma using bioluminescent sensor proteins and a smartphone R Arts, I Den Hartog, SE Zijlema, V Thijssen, SHE Van Der Beelen, ... Analytical chemistry 88 (8), 4525-4532, 2016 | 116 | 2016 |
| Variation of linker length in ratiometric fluorescent sensor proteins allows rational tuning of Zn (II) affinity in the picomolar to femtomolar range EMWM van Dongen, TH Evers, LM Dekkers, EW Meijer, LWJ Klomp, ... Journal of the American Chemical Society 129 (12), 3494-3495, 2007 | 116 | 2007 |
| An optical sensor based on a photonic polymer film to detect calcium in serum M Moirangthem, R Arts, M Merkx, APHJ Schenning Advanced functional materials 26 (8), 1154-1160, 2016 | 112 | 2016 |
| Ratiometric fluorescent sensor proteins with subnanomolar affinity for Zn (II) based on copper chaperone domains EMWM van Dongen, LM Dekkers, K Spijker, EW Meijer, LWJ Klomp, ... Journal of the American Chemical Society 128 (33), 10754-10762, 2006 | 109 | 2006 |
| Engineering genetically encoded FRET sensors L Lindenburg, M Merkx Sensors 14 (7), 11691-11713, 2014 | 105 | 2014 |
| High resolution imaging of collagen organisation and synthesis using a versatile collagen specific probe RA Boerboom, KN Krahn, RTA Megens, MAMJ van Zandvoort, M Merkx, ... Journal of structural biology 159 (3), 392-399, 2007 | 104 | 2007 |
| Mitochondrial and ER-Targeted eCALWY Probes Reveal High Levels of Free Zn2+ P Chabosseau, E Tuncay, G Meur, EA Bellomo, A Hessels, S Hughes, ... ACS chemical biology 9 (9), 2111-2120, 2014 | 101 | 2014 |
| Electrochemical reduction of NO by hemin adsorbed at pyrolitic graphite MT de Groot, M Merkx, AH Wonders, MTM Koper Journal of the American Chemical Society 127 (20), 7579-7586, 2005 | 101 | 2005 |
| Enhanced sensitivity of FRET‐based protease sensors by redesign of the GFP dimerization interface JL Vinkenborg, TH Evers, SWA Reulen, EW Meijer, M Merkx ChemBioChem 8 (10), 1119-1121, 2007 | 99 | 2007 |
