SIGNOR: a database of causal relationships between biological entities L Perfetto, L Briganti, A Calderone, A Cerquone Perpetuini, M Iannuccelli, ... Nucleic acids research 44 (D1), D548-D554, 2016 | 247 | 2016 |
Laser capture microdissection and protein microarray analysis of human non-small cell lung cancer: differential epidermal growth factor receptor (EGPR) phosphorylation events … AJ VanMeter, AS Rodriguez, ED Bowman, J Jen, CC Harris, J Deng, ... Molecular & Cellular Proteomics 7 (10), 1902-1924, 2008 | 136 | 2008 |
Deep proteomics of breast cancer cells reveals that metformin rewires signaling networks away from a pro-growth state F Sacco, A Silvestri, D Posca, S Pirrò, PF Gherardini, L Castagnoli, ... Cell systems 2 (3), 159-171, 2016 | 88 | 2016 |
Protein pathway biomarker analysis of human cancer reveals requirement for upfront cellular-enrichment processing A Silvestri, A Colombatti, VS Calvert, J Deng, E Mammano, C Belluco, ... Laboratory investigation 90 (5), 787-796, 2010 | 72 | 2010 |
Heterogeneous pathway activation and drug response modelled in colorectal-tumor-derived 3D cultures D Schumacher, G Andrieux, K Boehnke, M Keil, A Silvestri, M Silvestrov, ... PLOS Genetics 15 (3), e1008076, 2019 | 70 | 2019 |
Metformin induces apoptosis and downregulates pyruvate kinase M2 in breast cancer cells only when grown in nutrient-poor conditions A Silvestri, F Palumbo, I Rasi, D Posca, T Pavlidou, S Paoluzi, ... PloS one 10 (8), e0136250, 2015 | 49 | 2015 |
Individualized therapy for metastatic colorectal cancer A Silvestri, E Pin, A Huijbers, R Pellicani, EM Parasido, M Pierobon, ... Journal of internal medicine 274 (1), 1-24, 2013 | 43 | 2013 |
Three-Dimensional Patient-Derived In Vitro Sarcoma Models: Promising Tools for Improving Clinical Tumor Management M Gaebler, A Silvestri, J Haybaeck, P Reichardt, CD Lowery, LF Stancato, ... Frontiers in Oncology 7, 203, 2017 | 42 | 2017 |
The solution structure of EMILIN1 globular C1q domain reveals a disordered insertion necessary for interaction with the α4β1 integrin G Verdone, R Doliana, A Corazza, SA Colebrooke, P Spessotto, S Bot, ... Journal of Biological Chemistry 283 (27), 18947-18956, 2008 | 40 | 2008 |
Pilot phase I/II personalized therapy trial for metastatic colorectal cancer: evaluating the feasibility of protein pathway activation mapping for stratifying patients to … M Pierobon, A Silvestri, A Spira, A Reeder, E Pin, S Banks, E Parasido, ... Journal of proteome research 13 (6), 2846-2855, 2014 | 36 | 2014 |
Influence of eukaryotic translation initiation factor 6 on non–small cell lung cancer development and progression N Gantenbein, E Bernhart, I Anders, N Golob-Schwarzl, S Krassnig, ... European Journal of Cancer 101, 165-180, 2018 | 34 | 2018 |
A pilot characterization of human lung NSCLC by protein pathway activation mapping A Zupa, G Improta, A Silvestri, E Pin, J Deng, M Aieta, P Musto, D Nitti, ... Journal of Thoracic Oncology 7 (12), 1755-1766, 2012 | 34 | 2012 |
From chemotherapy to combined targeted therapeutics: in vitro and in vivo models to decipher intra-tumor heterogeneity G Gambara, M Gaebler, U Keilholz, CRA Regenbrecht, A Silvestri Frontiers in pharmacology 9, 77, 2018 | 26 | 2018 |
From chemotherapy to combined targeted therapeutics: in vitro and in vivo models to decipher intra-tumor heterogeneity G Gambara, M Gaebler, U Keilholz, CRA Regenbrecht, A Silvestri Frontiers in Pharmacology 9, 77, 2018 | 26 | 2018 |
Reverse phase protein microarrays: fluorometric and colorimetric detection RI Gallagher, A Silvestri, EF Petricoin, LA Liotta, V Espina Protein Microarray for Disease Analysis, 275-301, 2011 | 26 | 2011 |
Protein pathway activation mapping of colorectal metastatic progression reveals metastasis-specific network alterations A Silvestri, V Calvert, C Belluco, M Lipsky, R De Maria, J Deng, ... Clinical & experimental metastasis 30 (3), 309-316, 2013 | 25 | 2013 |
Protein drug target activation homogeneity in the face of intra-tumor heterogeneity: implications for precision medicine EM Parasido, A Silvestri, V Canzonieri, C Belluco, MG Diodoro, M Milione, ... Oncotarget 8 (30), 48534, 2017 | 10 | 2017 |
Academic collaborative models fostering the translation of physiological in vitro systems from basic research into drug discovery A Silvestri, F Vicente, MJ Vicent, B Stechmann, W Fecke Drug Discovery Today, 2021 | 6 | 2021 |
In Vitro Three-Dimensional Cell Cultures as Tool for Precision Medicine A Silvestri, D Schumacher, M Silvestrov, R Schäfer, C Reinhard, ... Mechanisms of Molecular Carcinogenesis–Volume 2, 281-313, 2017 | 6 | 2017 |
Use of gene expression signatures to identify origin of primary and therapeutic strategies for patients with advanced solid tumors. SD Hsu, MK Kim, A Foye, A Silvestri, HK Lyerly, M Morse, E Petricoin III, ... Journal of Clinical Oncology 28 (15_suppl), 10504-10504, 2010 | 3 | 2010 |