Potential adjuvantic properties of innate immune stimuli HJ Warshakoon, JD Hood, MR Kimbrell, S Malladi, WY Wu, N Shukla, ... Human vaccines 5 (6), 381-394, 2009 | 114 | 2009 |
Determinants of activity at human Toll-like receptors 7 and 8: quantitative structure–activity relationship (QSAR) of diverse heterocyclic scaffolds E Yoo, DB Salunke, D Sil, X Guo, ACD Salyer, AR Hermanson, M Kumar, ... Journal of medicinal chemistry 57 (19), 7955-7970, 2014 | 85 | 2014 |
Toll-like receptor-8 agonistic activities in C2, C4, and C8 modified thiazolo [4, 5-c] quinolines HP Kokatla, E Yoo, DB Salunke, D Sil, CF Ng, R Balakrishna, SS Malladi, ... Organic & biomolecular chemistry 11 (7), 1179-1198, 2013 | 71 | 2013 |
Exquisite Selectivity for Human Toll-Like Receptor 8 in Substituted Furo[2,3-c]quinolines HP Kokatla, D Sil, SS Malladi, R Balakrishna, AR Hermanson, LM Fox, ... Journal of medicinal chemistry 56 (17), 6871-6885, 2013 | 69 | 2013 |
Structure-based design of human TLR8-specific agonists with augmented potency and adjuvanticity M Beesu, G Caruso, ACD Salyer, KK Khetani, D Sil, M Weerasinghe, ... Journal of medicinal chemistry 58 (19), 7833-7849, 2015 | 66 | 2015 |
Structure‐based design of novel human Toll‐like receptor 8 agonists HP Kokatla, D Sil, H Tanji, U Ohto, SS Malladi, LM Fox, T Shimizu, ... ChemMedChem 9 (4), 719-723, 2014 | 53 | 2014 |
Bound to shock: protection from lethal endotoxemic shock by a novel, nontoxic, alkylpolyamine lipopolysaccharide sequestrant D Sil, A Shrestha, MR Kimbrell, TB Nguyen, AK Adisechan, R Balakrishna, ... Antimicrobial agents and chemotherapy 51 (8), 2811-2819, 2007 | 38 | 2007 |
Stereoselective alkenylation of a 1,3-disubstituted pyrazol-5-one through ring transformation of 2H-pyran-2-ones D Sil, R Kumar, A Sharon, PR Maulik, VJ Ram Tetrahedron letters 46 (22), 3807-3809, 2005 | 31 | 2005 |
Synthesis of a highly water-soluble derivative of amphotericin B with attenuated proinflammatory activity SA Adediran, TP Day, D Sil, MR Kimbrell, HJ Warshakoon, SS Malladi, ... Molecular pharmaceutics 6 (5), 1582-1590, 2009 | 28 | 2009 |
Polycation fluorination improves intraperitoneal siRNA delivery in metastatic pancreatic cancer Y Hang, S Tang, W Tang, D Větvička, C Zhang, Y Xie, F Yu, A Yu, D Sil, ... Journal of Controlled Release 333, 139-150, 2021 | 27 | 2021 |
Intraperitoneal siRNA nanoparticles for augmentation of gemcitabine efficacy in the treatment of pancreatic cancer S Tang, Y Hang, L Ding, W Tang, A Yu, C Zhang, D Sil, Y Xie, D Oupicky Molecular pharmaceutics 18 (12), 4448-4458, 2021 | 25 | 2021 |
Imbuing aqueous solubility to amphotericin B and nystatin with a vitamin TP Day, D Sil, NM Shukla, A Anbanandam, VW Day, SA David Molecular pharmaceutics 8 (1), 297-301, 2011 | 21 | 2011 |
Perfluorocarbon nanoemulsions enhance therapeutic siRNA delivery in the treatment of pulmonary fibrosis L Ding, S Tang, W Tang, DD Mosley, A Yu, D Sil, S Romanova, KL Bailey, ... Advanced Science 9 (8), 2103676, 2022 | 20 | 2022 |
Controlling plasma protein binding: structural correlates of interactions of hydrophobic polyamine endotoxin sequestrants with human serum albumin TB Nguyen, EVK Suresh Kumar, D Sil, SJ Wood, KA Miller, ... Molecular pharmaceutics 5 (6), 1131-1137, 2008 | 18 | 2008 |
An innovative approach to the synthesis of substituted benzaldehydes through carbanion induced ring transformation of suitably functionalized 2H-pyran-2-ones R Pratap, D Sil, VJ Ram Tetrahedron letters 45 (29), 5743-5745, 2004 | 17 | 2004 |
Oral delivery of nucleic acid therapies for local and systemic action N Kumari, K Siddhanta, S Panja, V Joshi, C Jogdeo, E Kapoor, R Khan, ... Pharmaceutical Research 40 (1), 107-122, 2023 | 14 | 2023 |
Structure–activity relationships of lipopolysaccharide sequestration in guanylhydrazone-bearing lipopolyamines W Wu, D Sil, ML Szostak, SS Malladi, HJ Warshakoon, MR Kimbrell, ... Bioorganic & medicinal chemistry 17 (2), 709-715, 2009 | 14 | 2009 |
A concise synthesis of highly functionalized α,β-unsaturated γ-butyrolactones through ring contraction of 2H-pyran-2-ones D Sil, A Sharon, PR Maulik, VJ Ram Tetrahedron letters 45 (33), 6273-6276, 2004 | 13 | 2004 |
Dually active polycation/miRNA nanoparticles for the treatment of fibrosis in alcohol-associated liver disease C Zhang, Y Hang, W Tang, D Sil, HC Jensen-Smith, RG Bennett, ... Pharmaceutics 14 (3), 669, 2022 | 10 | 2022 |
Biophysical mechanisms of the neutralization of endotoxins by lipopolyamines D Sil, L Heinbockel, Y Kaconis, M Rössle, P Garidel, T Gutsmann, ... The open biochemistry journal 7, 82, 2013 | 9 | 2013 |