Matt Sazinsky
Matt Sazinsky
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Dioxygen activation and methane hydroxylation by soluble methane monooxygenase: a tale of two irons and three proteins
M Merkx, DA Kopp, MH Sazinsky, JL Blazyk, J Müller, SJ Lippard
Angewandte Chemie International Edition 40 (15), 2782-2807, 2001
Crystal structure of the toluene/o-xylene monooxygenase hydroxylase from Pseudomonas stutzeri OX1: insight into the substrate specificity, substrate channeling, and active site …
MH Sazinsky, J Bard, A Di Donato, SJ Lippard
Journal of Biological Chemistry 279 (29), 30600-30610, 2004
Correlating structure with function in bacterial multicomponent monooxygenases and related diiron proteins
MH Sazinsky, SJ Lippard
Accounts of chemical research 39 (8), 558-566, 2006
Structural insights into dioxygen-activating copper enzymes
AC Rosenzweig, MH Sazinsky
Current Opinion in Structural Biology 16 (6), 729-735, 2006
Structure of the ATP binding domain from the Archaeoglobus fulgidus Cu+-ATPase
MH Sazinsky, AK Mandal, JM Arguello, AC Rosenzweig
Journal of Biological Chemistry 281 (16), 11161-11166, 2006
Product bound structures of the soluble methane monooxygenase hydroxylase from Methylococcus capsulatus (Bath): protein motion in the α-subunit
MH Sazinsky, SJ Lippard
Journal of the American Chemical Society 127 (16), 5814-5825, 2005
X-ray Structure of a Hydroxylase−Regulatory Protein Complex from a Hydrocarbon-Oxidizing Multicomponent Monooxygenase, Pseudomonas sp. OX1 Phenol Hydroxylase …
MH Sazinsky, PW Dunten, MS McCormick, A DiDonato, SJ Lippard
Biochemistry 45 (51), 15392-15404, 2006
Methane monooxygenase: functionalizing methane at iron and copper
MH Sazinsky, SJ Lippard
Sustaining life on planet earth: Metalloenzymes mastering dioxygen and other …, 2015
Structure of the Actuator Domain from the Archaeoglobus fulgidus Cu+-ATPase,
MH Sazinsky, S Agarwal, JM Argüello, AC Rosenzweig
Biochemistry 45 (33), 9949-9955, 2006
Aktivierung von Disauerstoff und Hydroxylierung von Methan durch lösliche Methan‐Monooxygenase: eine Geschichte von zwei Eisenatomen und drei Proteinen
M Merkx, DA Kopp, MH Sazinsky, JL Blazyk, J Müller, SJ Lippard
Angewandte Chemie 113 (15), 2860-2888, 2001
Structure and mechanism of styrene monooxygenase reductase: new insight into the FAD-transfer reaction
E Morrison, A Kantz, GT Gassner, MH Sazinsky
Biochemistry 52 (35), 6063-6075, 2013
X-ray crystal structure of alcohol products bound at the active site of soluble methane monooxygenase hydroxylase
DA Whittington, MH Sazinsky, SJ Lippard
Journal of the American Chemical Society 123 (8), 1794-1795, 2001
An artificial gene for human porphobilinogen synthase allows comparison of an allelic variation implicated in susceptibility to lead poisoning
EK Jaffe, M Volin, CR Bronson-Mullins, RL Dunbrack, J Kervinen, ...
Journal of Biological Chemistry 275 (4), 2619-2626, 2000
X-ray Crystal Structures of Manganese(II)-Reconstituted and Native Toluene/o-Xylene Monooxygenase Hydroxylase Reveal Rotamer Shifts in Conserved …
MS McCormick, MH Sazinsky, KL Condon, SJ Lippard
Journal of the American Chemical Society 128 (47), 15108-15110, 2006
Characterization and structure of a Zn2+ and [2Fe-2S]-containing copper chaperone from Archaeoglobus fulgidus
MH Sazinsky, B LeMoine, M Orofino, R Davydov, KZ Bencze, ...
Journal of Biological Chemistry 282 (35), 25950-25959, 2007
Preparation and X-ray structures of metal-free, dicobalt and dimanganese forms of soluble methane monooxygenase hydroxylase from Methylococcus capsulatus (Bath)
MH Sazinsky, M Merkx, E Cadieux, S Tang, SJ Lippard
Biochemistry 43 (51), 16263-16276, 2004
Active Site Threonine Facilitates Proton Transfer during Dioxygen Activation at the Diiron Center of Toluene/o-Xylene Monooxygenase Hydroxylase
WJ Song, MS McCormick, RK Behan, MH Sazinsky, W Jiang, J Lin, ...
Journal of the American Chemical Society 132 (39), 13582-13585, 2010
Structure and interactions of the C‐terminal metal binding domain of Archaeoglobus fulgidus CopA
S Agarwal, D Hong, NK Desai, MH Sazinsky, JM Argüello, ...
Proteins: Structure, Function, and Bioinformatics 78 (11), 2450-2458, 2010
Determination by X-ray Absorption Spectroscopy of the Fe− Fe Separation in the Oxidized Form of the Hydroxylase of Methane Monooxygenase Alone and in the Presence of MMOD
D Jackson Rudd, MH Sazinsky, M Merkx, SJ Lippard, B Hedman, ...
Inorganic chemistry 43 (15), 4579-4589, 2004
Tracking a defined route for O2 migration in a dioxygen-activating diiron enzyme
WJ Song, G Gucinski, MH Sazinsky, SJ Lippard
Proceedings of the National Academy of Sciences 108 (36), 14795-14800, 2011
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