Ilia D. Vainchtein, PhD
Ilia D. Vainchtein, PhD
Scientist in Neuroimmunology, Janssen R&D, San Diego
Verified email at
Cited by
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Transcriptomic analysis of purified human cortical microglia reveals age-associated changes
TF Galatro, IR Holtman, AM Lerario, ID Vainchtein, N Brouwer, PR Sola, ...
Nature neuroscience 20 (8), 1162-1171, 2017
Astrocyte-derived interleukin-33 promotes microglial synapse engulfment and neural circuit development
ID Vainchtein, G Chin, FS Cho, KW Kelley, JG Miller, EC Chien, ...
Science 359 (6381), 1269-1273, 2018
Microglial remodeling of the extracellular matrix promotes synapse plasticity
PT Nguyen, LC Dorman, S Pan, ID Vainchtein, RT Han, H Nakao-Inoue, ...
Cell 182 (2), 388-403. e15, 2020
Astrocytes and microglia: in sickness and in health
ID Vainchtein, AV Molofsky
Trends in Neurosciences 43 (3), 144-154, 2020
In acute experimental autoimmune encephalomyelitis, infiltrating macrophages are immune activated, whereas microglia remain immune suppressed
ID Vainchtein, J Vinet, N Brouwer, S Brendecke, G Biagini, K Biber, ...
Glia 62 (10), 1724-1735, 2014
Circuit and molecular architecture of a ventral hippocampal network
MM Gergues, KJ Han, HS Choi, B Brown, KJ Clausing, VS Turner, ...
Nature Neuroscience 23 (11), 1444-1452, 2020
Survival and functionality of human induced pluripotent stem cell‐derived oligodendrocytes in a nonhuman primate model for multiple sclerosis
A Thiruvalluvan, M Czepiel, YA Kap, I Mantingh-Otter, I Vainchtein, ...
Stem cells translational medicine 5 (11), 1550-1561, 2016
Microglia are less pro‐inflammatory than myeloid infiltrates in the hippocampus of mice exposed to status epilepticus
J Vinet, ID Vainchtein, C Spano, C Giordano, D Bordini, G Curia, ...
Glia 64 (8), 1350-1362, 2016
Glia open access database (GOAD): a comprehensive gene expression encyclopedia of glia cells in health and disease
IR Holtman, M Noback, M Bijlsma, KN Duong, MA van der Geest, ...
Glia 63 (9), 1495-1506, 2015
Regulatory T-cells inhibit microglia-induced pain hypersensitivity in female mice
JA Kuhn, ID Vainchtein, J Braz, K Hamel, M Bernstein, V Craik, ...
Elife 10, e69056, 2021
Isolation of microglia and immune infiltrates from mouse and primate central nervous system
TF Galatro, ID Vainchtein, N Brouwer, EWGM Boddeke, BJL Eggen
Inflammation, 333-342, 2017
Regionally diverse astrocyte subtypes and their heterogeneous response to EAE
M Borggrewe, C Grit, ID Vainchtein, N Brouwer, EM Wesseling, JD Laman, ...
Glia 69 (5), 1140-1154, 2021
In situ and transcriptomic identification of microglia in synapse-rich regions of the developing zebrafish brain
NJ Silva, LC Dorman, ID Vainchtein, NC Horneck, AV Molofsky
Nature communications 12 (1), 1-12, 2021
Rapid deployment of SARS-CoV-2 testing: The CLIAHUB
ED Crawford, I Acosta, V Ahyong, EC Anderson, S Arevalo, D Asarnow, ...
PLoS pathogens 16 (10), e1008966, 2020
Enhancing GAT-3 in thalamic astrocytes promotes resilience to brain injury in rodents
FS Cho, ID Vainchtein, Y Voskobiynyk, AR Morningstar, F Aparicio, ...
Science translational medicine 14 (652), eabj4310, 2022
Microglial pattern recognition via IL-33 promotes synaptic refinement in developing corticothalamic circuits in mice
RT Han, ID Vainchtein, JCM Schlachetzki, FS Cho, LC Dorman, E Ahn, ...
Journal of Experimental Medicine 220 (2), e20220605, 2022
A type I interferon response defines a conserved microglial state required for effective phagocytosis
LC Dorman, PT Nguyen, CC Escoubas, ID Vainchtein, Y Xiao, PV Lidsky, ...
bioRxiv, 2021
Characterizing microglial gene expression in a model of secondary progressive multiple sclerosis
ID Vainchtein, AM Alsema, ML Dubbelaar, C Grit, J Vinet, ...
Glia 71 (3), 588-601, 2023
Interleukin-33 coordinates a microglial phagocytic response and limits corticothalamic excitability and seizure susceptibility
RT Han, ID Vainchtein, JCM Schlachetzki, FS Cho, LC Dorman, T Johung, ...
bioRxiv, 2021
Human microglia transcriptome and cross-species analysis
TFA Galatro, IR Holtman, N Brouwer, P Sola, GN Reis, ID Vainchtein, ...
Glia, 2015
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