Emergence of an outbreak-associated Clostridium difficile variant with increased virulence C Quesada-Gómez, D López-Ureña, L Acuña-Amador, ... Journal of clinical microbiology 53 (4), 1216-1226, 2015 | 78 | 2015 |
Spread of epidemic Clostridium difficile NAP1/027 in Latin America: case reports in Panama D López-Ureña, C Quesada-Gómez, E Miranda, M Fonseca, ... Journal of medical microbiology 63 (2), 322-324, 2014 | 49 | 2014 |
Novel Clade C-I Clostridium difficile strains escape diagnostic tests, differ in pathogenicity potential and carry toxins on extrachromosomal elements G Ramírez-Vargas, D López-Ureña, A Badilla, J Orozco-Aguilar, T Murillo, ... Scientific reports 8 (1), 13951, 2018 | 39 | 2018 |
A Clostridium difficile lineage endemic to Costa Rican hospitals is multidrug resistant by acquisition of chromosomal mutations and novel mobile genetic elements G Ramírez-Vargas, C Quesada-Gómez, L Acuña-Amador, D López-Ureña, ... Antimicrobial agents and chemotherapy 61 (4), 10.1128/aac. 02054-16, 2017 | 31 | 2017 |
Toxin B Variants from Clostridium difficile Strains VPI 10463 and NAP1/027 Share Similar Substrate Profile and Cellular Intoxication Kinetics but Use Different Host … D López-Ureña, J Orozco-Aguilar, Y Chaves-Madrigal, A Ramírez-Mata, ... Toxins 11 (6), 348, 2019 | 29 | 2019 |
Transforming growth factor β1/SMAD signaling pathway activation protects the intestinal epithelium from Clostridium difficile toxin A-induced damage CM Tinoco-Veras, AAQA Santos, J Stipursky, M Meloni, APB Araujo, ... Infection and immunity 85 (10), 10.1128/iai. 00430-17, 2017 | 29 | 2017 |
Analysis of TcdB proteins within the hypervirulent clade 2 reveals an impact of RhoA glucosylation on Clostridium difficile proinflammatory activities C Quesada-Gómez, D López-Ureña, N Chumbler, HK Kroh, ... Infection and immunity 84 (3), 856-865, 2016 | 28 | 2016 |
A MLST Clade 2 Clostridium difficile strain with a variant TcdB induces severe inflammatory and oxidative response associated with mucosal disruption CL Costa, D López-Ureña, T de Oliveira Assis, RA Ribeiro, ROS Silva, ... Anaerobe 40, 76-84, 2016 | 23 | 2016 |
Predominance and high antibiotic resistance of the emerging Clostridium difficile genotypes NAPCR1 and NAP9 in a Costa Rican hospital over a 2-year period … D López-Ureña, C Quesada-Gómez, M Montoya-Ramírez, ... Emerging microbes & infections 5 (1), 1-5, 2016 | 21 | 2016 |
Cytotoxicity of Clostridium difficile toxins A and B requires an active and functional SREBP‐2 pathway P Papatheodorou, S Song, D López‐Ureña, A Witte, F Marques, GS Ost, ... The FASEB journal 33 (4), 4883-4892, 2019 | 16 | 2019 |
Community-acquired Clostridium difficile NAP1/027-associated diarrhea in an eighteen month old child C Quesada-Gómez, P Vargas, D López-Ureña, ... Anaerobe 18 (6), 581-583, 2012 | 12 | 2012 |
Identification and antimicrobial susceptibility of obligate anaerobic bacteria from clinical samples of animal origin M Mayorga, E Rodríguez-Cavallini, D López-Ureña, E Barquero-Calvo, ... Anaerobe 36, 19-24, 2015 | 10 | 2015 |
Proteogenomic analysis of the Clostridium difficile exoproteome reveals a correlation between phylogenetic distribution and virulence potential C Quesada-Gómez, T Murillo, G Arce, A Badilla-Lobo, C Castro-Peña, ... Anaerobe 62, 102151, 2020 | 8 | 2020 |
Toxin B variants from Clostridium difficile strains VPI 10463 and NAP1/027 share similar substrate profile and cellular intoxication kinetics but use different host cell entry … D López-Ureña, J Orozco-Aguilar, Y Chaves-Madrigal, A Ramirez-Mata, ... | 6 | 2019 |
TGF-β1/SMADs signaling pathway activation protects intestinal epithelium from Clostridium difficile toxin A-induced damage CM Tinoco-Veras, A Santos, J Stipursky, M Meloni, APB Araujo, ... Infect Immun 85 (10), 1-13, 2017 | 4 | 2017 |
Avian Botulism Type C in a Commercial Poultry Farm: First Report in Central America E Rodríguez-Cavallini, D López-Ureña, T Román, C Quesada-Gómez J Bacteriol Parasitol 9 (337), 2, 2018 | | 2018 |
Panel de Gtpasas glicosiladas por diferentes TcdBs de Clostridium difficile y su relación con el potencial patogénico de distintas cepas D López Ureña | | 2016 |
A MLST Clade 2 Clostridium difficile strain with a variant TcdB induces severe inflammatory and oxidative response associated with mucosal disruption C Leite Costa, D López Ureña, T de Oliveira Assis, RA Ribeiro, ... | | 2016 |
Clostridium difficile from the hypervirulent clade II isolated from Costa Rica with a variant toxin B C Quesada-Gomez, D Lopez-Urena, C Castro, H Kroh, N Chumbler, ... TROPICAL MEDICINE & INTERNATIONAL HEALTH 20, 296-296, 2015 | | 2015 |
Emergence of an outbreak-associated Clostridium difficile variant with increased virulence C Guzman-Verri, C Quesada-Gómez, D López-Ureña, L Acuña-Amador, ... Journal of Clinical Microbiology, 2015 | | 2015 |