Follow
Kevin Madauss
Title
Cited by
Cited by
Year
Structural analyses reveal phosphatidyl inositols as ligands for the NR5 orphan receptors SF-1 and LRH-1
IN Krylova, EP Sablin, J Moore, RX Xu, GM Waitt, JA MacKay, ...
Cell 120 (3), 343-355, 2005
4592005
Selective class IIa histone deacetylase inhibition via a nonchelating zinc-binding group
M Lobera, KP Madauss, DT Pohlhaus, QG Wright, M Trocha, DR Schmidt, ...
Nature chemical biology 9 (5), 319-325, 2013
3042013
A Ligand-mediated Hydrogen Bond Network Required for the Activation of the Mineralocorticoid Receptor*[boxs]
RK Bledsoe, KP Madauss, JA Holt, CJ Apolito, MH Lambert, KH Pearce, ...
Journal of Biological Chemistry 280 (35), 31283-31293, 2005
2032005
Crystallization of protein–ligand complexes
AM Hassell, G An, RK Bledsoe, JM Bynum, HL Carter, SJJ Deng, ...
Acta Crystallographica Section D: Biological Crystallography 63 (1), 72-79, 2007
2022007
A Structural and in Vitro Characterization of Asoprisnil: A Selective Progesterone Receptor Modulator
KP Madauss, ET Grygielko, SJ Deng, AC Sulpizio, TB Stanley, C Wu, ...
Molecular endocrinology 21 (5), 1066-1081, 2007
1612007
Structure of neurolysin reveals a deep channel that limits substrate access
CK Brown, K Madauss, W Lian, MR Beck, WD Tolbert, DW Rodgers
Proceedings of the National Academy of Sciences 98 (6), 3127-3132, 2001
1492001
Conformationally constrained farnesoid X receptor (FXR) agonists: Naphthoic acid-based analogs of GW 4064
A Akwabi-Ameyaw, JY Bass, RD Caldwell, JA Caravella, L Chen, ...
Bioorganic & medicinal chemistry letters 18 (15), 4339-4343, 2008
1222008
Progesterone receptor ligand binding pocket flexibility: crystal structures of the norethindrone and mometasone furoate complexes
KP Madauss, SJ Deng, RJH Austin, MH Lambert, I McLay, J Pritchard, ...
Journal of medicinal chemistry 47 (13), 3381-3387, 2004
902004
Design and x-ray crystal structures of high-potency nonsteroidal glucocorticoid agonists exploiting a novel binding site on the receptor
K Biggadike, RK Bledsoe, DM Coe, TWJ Cooper, D House, MA Iannone, ...
Proceedings of the National Academy of Sciences 106 (43), 18114-18119, 2009
722009
The evolution of progesterone receptor ligands
KP Madauss, EL Stewart, SP Williams
Medicinal research reviews 27 (3), 374-400, 2007
652007
Conformationally constrained farnesoid X receptor (FXR) agonists: heteroaryl replacements of the naphthalene
JY Bass, JA Caravella, L Chen, KL Creech, DN Deaton, KP Madauss, ...
Bioorganic & medicinal chemistry letters 21 (4), 1206-1213, 2011
642011
FXR agonist activity of conformationally constrained analogs of GW 4064
A Akwabi-Ameyaw, JY Bass, RD Caldwell, JA Caravella, L Chen, ...
Bioorganic & medicinal chemistry letters 19 (16), 4733-4739, 2009
602009
Substituted isoxazole analogs of farnesoid X receptor (FXR) agonist GW4064
JY Bass, RD Caldwell, JA Caravella, L Chen, KL Creech, DN Deaton, ...
Bioorganic & medicinal chemistry letters 19 (11), 2969-2973, 2009
582009
The first X-ray crystal structure of the glucocorticoid receptor bound to a non-steroidal agonist
KP Madauss, RK Bledsoe, I Mclay, EL Stewart, IJ Uings, G Weingarten, ...
Bioorganic & medicinal chemistry letters 18 (23), 6097-6099, 2008
512008
Pyrrolidinyl pyridone and pyrazinone analogues as potent inhibitors of prolyl oligopeptidase (POP)
CD Haffner, CJ Diaz, AB Miller, RA Reid, KP Madauss, A Hassell, ...
Bioorganic & medicinal chemistry letters 18 (15), 4360-4363, 2008
472008
Discovery of non-steroidal mifepristone mimetics: Pyrazoline-based PR antagonists
DG Jones, X Liang, EL Stewart, RA Noe, LS Kallander, KP Madauss, ...
Bioorganic & medicinal chemistry letters 15 (13), 3203-3206, 2005
402005
Conformationally constrained farnesoid X receptor (FXR) agonists: alternative replacements of the stilbene
A Akwabi-Ameyaw, JA Caravella, L Chen, KL Creech, DN Deaton, ...
Bioorganic & medicinal chemistry letters 21 (20), 6154-6160, 2011
382011
The human ACC2 CT-domain C-terminus is required for full functionality and has a novel twist
KP Madauss, WA Burkhart, TG Consler, DJ Cowan, WK Gottschalk, ...
Acta Crystallographica Section D: Biological Crystallography 65 (5), 449-461, 2009
322009
Novel scaffolds for inhibition of Cruzipain identified from high-throughput screening of anti-kinetoplastid chemical boxes
E Salas-Sarduy, LU Landaburu, J Karpiak, KP Madauss, JJ Cazzulo, ...
Scientific reports 7 (1), 1-12, 2017
292017
AKT inhibition impairs PCNA ubiquitylation and triggers synthetic lethality in homologous recombination-deficient cells submitted to replication stress
F Villafañez, IA García, S Carbajosa, MF Pansa, S Mansilla, MC Llorens, ...
Oncogene 38 (22), 4310-4324, 2019
232019
The system can't perform the operation now. Try again later.
Articles 1–20