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Jason Gehrke
Jason Gehrke
Dirección de correo verificada de g.harvard.edu
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CRISPResso2 provides accurate and rapid genome editing sequence analysis
K Clement, H Rees, MC Canver, JM Gehrke, R Farouni, JY Hsu, MA Cole, ...
Nature biotechnology 37 (3), 224-226, 2019
9302019
An APOBEC3A-Cas9 base editor with minimized bystander and off-target activities
JM Gehrke, O Cervantes, MK Clement, Y Wu, J Zeng, DE Bauer, L Pinello, ...
Nature biotechnology 36 (10), 977-982, 2018
4122018
Directed evolution of adenine base editors with increased activity and therapeutic application
NM Gaudelli, DK Lam, HA Rees, NM Solá-Esteves, LA Barrera, DA Born, ...
Nature biotechnology 38 (7), 892-900, 2020
4092020
Therapeutic base editing of human hematopoietic stem cells
J Zeng, Y Wu, C Ren, J Bonanno, AH Shen, D Shea, JM Gehrke, ...
Nature medicine 26 (4), 535-541, 2020
2252020
A dual role of caspase-8 in triggering and sensing proliferation-associated DNA damage, a key determinant of liver cancer development
Y Boege, M Malehmir, ME Healy, K Bettermann, A Lorentzen, M Vucur, ...
Cancer cell 32 (3), 342-359. e10, 2017
1422017
The Ino80 complex prevents invasion of euchromatin into silent chromatin
Y Xue, C Van, SK Pradhan, T Su, J Gehrke, BG Kuryan, T Kitada, ...
Genes & development 29 (4), 350-355, 2015
512015
Accurate and rapid analysis of genome editing data from nucleases and base editors with CRISPResso2
K Clement, H Rees, MC Canver, JM Gehrke, R Farouni, JY Hsu, MA Cole, ...
Nature biotechnology 37 (3), 224, 2019
102019
Therapeutic Base Editing of Human Hematopoietic Stem Cells
J Zeng, Y Wu, C Ren, J Bonanno, AH Shen, D Shea, JM Gehrke, ...
Blood 134, 612, 2019
12019
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