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Jamie Simpson
Jamie Simpson
Puretech Health
Dirección de correo verificada de monash.edu
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Marine isocyanides and related natural products–structure, biosynthesis and ecology
MJ Garson, JS Simpson
Natural product reports 21 (1), 164-179, 2004
2072004
Neurokinin 1 receptor signaling in endosomes mediates sustained nociception and is a viable therapeutic target for prolonged pain relief
DD Jensen, TM Lieu, ML Halls, NA Veldhuis, WL Imlach, QN Mai, ...
Science Translational Medicine 9 (392), eaal3447, 2017
1922017
Targeted delivery of a model immunomodulator to the lymphatic system: comparison of alkyl ester versus triglyceride mimetic lipid prodrug strategies
S Han, T Quach, L Hu, A Wahab, WN Charman, VJ Stella, NL Trevaskis, ...
Journal of controlled release 177, 1-10, 2014
932014
Promiscuous 2-aminothiazoles (PrATs): a frequent hitting scaffold
SM Devine, MD Mulcair, CO Debono, EWW Leung, JWM Nissink, SS Lim, ...
Journal of medicinal chemistry 58 (3), 1205-1214, 2015
922015
The structure of the bacterial oxidoreductase enzyme DsbA in complex with a peptide reveals a basis for substrate specificity in the catalytic cycle of DsbA enzymes
JJ Paxman, NA Borg, J Horne, PE Thompson, Y Chin, P Sharma, ...
Journal of biological chemistry 284 (26), 17835-17845, 2009
812009
Terpene metabolites from the tropical marine sponge Axinyssa sp. nov.
JS Simpson, MJ Garson, JNA Hooper, EI Cline, CK Angerhofer
Australian journal of chemistry 50 (12), 1123-1128, 1997
721997
Mesenteric lymphatic dysfunction promotes insulin resistance and represents a potential treatment target in obesity
E Cao, MJ Watt, CJ Nowell, T Quach, JS Simpson, V De Melo Ferreira, ...
Nature metabolism 3 (9), 1175-1188, 2021
632021
Glyceride‐mimetic prodrugs incorporating self‐immolative spacers promote lymphatic transport, avoid first‐pass metabolism, and enhance oral bioavailability
L Hu, T Quach, S Han, SF Lim, P Yadav, D Senyschyn, NL Trevaskis, ...
Angewandte Chemie 128 (44), 13904-13909, 2016
632016
Mycalamides C and D, cytotoxic compounds from the marine sponge Stylinos n. species
JS Simpson, MJ Garson, JW Blunt, MHG Munro, JNA Hooper
Journal of natural products 63 (5), 704-706, 2000
622000
Synthesis of unsymmetrical 1, 1′-disubstituted bis (1, 2, 3-triazole) s using monosilylbutadiynes
BC Doak, MJ Scanlon, JS Simpson
Organic Letters 13 (3), 537-539, 2011
582011
Cyclodextrin molecular reactors
L Barr, PG Dumanski, CJ Easton, JB Harper, K Lee, SF Lincoln, AG Meyer, ...
Journal of inclusion phenomena and macrocyclic chemistry 50, 19-24, 2004
582004
Application of Fragment‐Based Screening to the Design of Inhibitors of Escherichia coli DsbA
LA Adams, P Sharma, B Mohanty, OV Ilyichova, MD Mulcair, ML Williams, ...
Angewandte Chemie 127 (7), 2207-2212, 2015
572015
Demonstration of co-polymerization in melamine–urea–formaldehyde reactions using 15N NMR correlation spectroscopy
A Philbrook, CJ Blake, N Dunlop, CJ Easton, MA Keniry, JS Simpson
Polymer 46 (7), 2153-2156, 2005
512005
Metallocyclodextrin catalysts for hydrolysis of phosphate triesters
L Barr, CJ Easton, K Lee, SF Lincoln, JS Simpson
Tetrahedron letters 43 (43), 7797-7800, 2002
502002
Folate biosynthesis–reappraisal of old and novel targets in the search for new antimicrobials
J Swarbrick, P Iliades, JS Simpson, I Macreadie
The Open Enzyme Inhibition Journal 1 (1), 12-33, 2008
492008
Design and evaluation of the performance of an NMR screening fragment library
BC Doak, CJ Morton, JS Simpson, MJ Scanlon
Australian Journal of Chemistry 66 (12), 1465-1472, 2013
472013
Structure and function of the oxidoreductase DsbA1 from Neisseria meningitidis
JP Vivian, J Scoullar, K Rimmer, SR Bushell, T Beddoe, MCJ Wilce, ...
Journal of molecular biology 394 (5), 931-943, 2009
472009
New chlorinated metabolites from the tropical marine sponge Dysidea herbacea
EJ Dumdei, JS Simpson, MJ Garson, KA Byriel, CHL Kennard
Australian journal of chemistry 50 (2), 139-144, 1997
471997
Biosynthesis of dichloroimines in the tropical marine sponge Stylotella aurantium
JS Simpson, P Raniga, MJ Garson
Tetrahedron letters 38 (45), 7947-7950, 1997
441997
Profiling the role of deacylation-reacylation in the lymphatic transport of a triglyceride-mimetic prodrug
S Han, L Hu, T Quach, JS Simpson, NL Trevaskis, CJH Porter
Pharmaceutical research 32, 1830-1844, 2015
402015
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Artículos 1–20