| Glycopeptide enkephalin analogues produce analgesia in mice: evidence for penetration of the blood-brain barrier. R Polt, F Porreca, LZ Szabo, EJ Bilsky, P Davis, TJ Abbruscato, TP Davis, ... Proceedings of the National Academy of Sciences 91 (15), 7114-7118, 1994 | 304 | 1994 |
| Preclinical assessment of candidate analgesic drugs: recent advances and future challenges SS Negus, TW Vanderah, MR Brandt, EJ Bilsky, L Becerra, D Borsook Journal of Pharmacology and Experimental Therapeutics 319 (2), 507-514, 2006 | 294 | 2006 |
| Probes for narcotic receptor mediated phenomena. 19. Synthesis of (+)-4-[(. alpha. R)-. alpha.-((2S, 5R)-4-Allyl-2, 5-dimethyl-1-piperazinyl)-3-methoxybenzyl]-N, N … SN Calderon, RB Rothman, F Porreca, JL Flippen-Anderson, RW McNutt, ... Journal of medicinal chemistry 37 (14), 2125-2128, 1994 | 291 | 1994 |
| SNC 80, a selective, nonpeptidic and systemically active opioid delta agonist. EJ Bilsky, SN Calderon, T Wang, RN Bernstein, P Davis, VJ Hruby, ... Journal of Pharmacology and Experimental Therapeutics 273 (1), 359-366, 1995 | 274 | 1995 |
| Opioid receptor types and subtypes: the delta receptor as a model PA Zaki, EJ Bilsky, TW Vanderah, J Lai, CJ Evans, F Porreca Annual review of pharmacology and toxicology 36 (1), 379-401, 1996 | 237 | 1996 |
| Accelerated communciation: Constitutive μ opioid receptor activation as a regulatory mechanism underlying narcotic tolerance and dependence Z Wang, EJ Bilsky, F Porreca, W Sadée Life sciences 54 (20), PL339-PL350, 1994 | 221 | 1994 |
| Antinociceptive profile of biphalin, a dimeric enkephalin analog. PJ Horan, A Mattia, EJ Bilsky, S Weber, TP Davis, HI Yamamura, ... Journal of Pharmacology and Experimental Therapeutics 265 (3), 1446-1454, 1993 | 164 | 1993 |
| Effects of naloxone and D-Phe-Cys-Tyr-D-Trp-Arg-Thr-Pen-Thr-NH2 and the protein kinase inhibitors H7 and H8 on acute morphine dependence and antinociceptive tolerance in mice. EJ Bilsky, RN Bernstein, Z Wang, W Sadée, F Porreca Journal of Pharmacology and Experimental Therapeutics 277 (1), 484-490, 1996 | 153 | 1996 |
| Inverse agonists and neutral antagonists at µ opioid receptor (MOR): possible role of basal receptor signaling in narcotic dependence D Wang, KM Raehal, EJ Bilsky, W Sadée Journal of neurochemistry 77 (6), 1590-1600, 2001 | 152 | 2001 |
| Enkephalin glycopeptide analogues produce analgesia with reduced dependence liability EJ Bilsky, RD Egleton, SA Mitchell, MM Palian, P Davis, JD Huber, ... Journal of medicinal chemistry 43 (13), 2586-2590, 2000 | 147 | 2000 |
| Competitive and non-competitive NMDA antagonists block the development of antinociceptive tolerance to morphine, but not to selective μ or δ opioid agonists in mice EJ Bilsky, CE Inturrisi, W Sadée, VJ Hruby, F Porreca Pain 68 (2-3), 229-237, 1996 | 138 | 1996 |
| Cocaine place preference is blocked by the δ-opioid receptor antagonist, naltrindole K Menkens, EJ Bilsky, KD Wild, PS Portoghese, LD Reid, F Porreca European journal of pharmacology 219 (2), 345-346, 1992 | 132 | 1992 |
| Basal opioid receptor activity, neutral antagonists, and therapeutic opportunities W Sadée, D Wang, EJ Bilsky Life sciences 76 (13), 1427-1437, 2005 | 119 | 2005 |
| Targeting pain-suppressed behaviors in preclinical assays of pain and analgesia: effects of morphine on acetic acid-suppressed feeding in C57BL/6J mice GW Stevenson, EJ Bilsky, SS Negus The Journal of Pain 7 (6), 408-416, 2006 | 115 | 2006 |
| Tests of opioid deficiency hypotheses of alcoholism LD Reid, JD Delconte, ML Nichols, EJ Bilsky, CL Hubbell Alcohol 8 (4), 247-257, 1991 | 112 | 1991 |
| Basal signaling activity of μ opioid receptor in mouse brain: role in narcotic dependence D Wang, KM Raehal, ET Lin, JJ Lowery, BL Kieffer, EJ Bilsky, W Sadee Journal of Pharmacology and Experimental Therapeutics 308 (2), 512-520, 2004 | 101 | 2004 |
| Opioidergic modulation of cocaine conditioned place preferences EJ Bilsky, MJ Montegut, CL Delong, LD Reid Life sciences 50 (14), PL85-PL90, 1992 | 99 | 1992 |
| In vivo characterization of 6β-naltrexol, an opioid ligand with less inverse agonist activity compared with naltrexone and naloxone in opioid-dependent mice KM Raehal, JJ Lowery, CM Bhamidipati, RM Paolino, JR Blair, D Wang, ... Journal of Pharmacology and Experimental Therapeutics 313 (3), 1150-1162, 2005 | 98 | 2005 |
| Synthesis, opioid receptor binding, and biological activities of naltrexone-derived pyrido-and pyrimidomorphinans S Ananthan, HS Kezar, RL Carter, SK Saini, KC Rice, JL Wells, P Davis, ... Journal of medicinal chemistry 42 (18), 3527-3538, 1999 | 94 | 1999 |
| Probes for Narcotic Receptor Mediated Phenomena. 23. Synthesis, Opioid Receptor Binding, and Bioassay of the Highly Selective δ Agonist (+)-4-[(αR)-α-((2S,5R)-4-Allyl-2,5-dimethyl … SN Calderon, KC Rice, RB Rothman, F Porreca, JL Flippen-Anderson, ... Journal of medicinal chemistry 40 (5), 695-704, 1997 | 94 | 1997 |
