| Opposite effects of training in rats with stable and progressive pulmonary hypertension ML Handoko, FS De Man, CM Happe, I Schalij, RJP Musters, N Westerhof, ... Circulation 120 (1), 42-49, 2009 | 265 | 2009 |
| Nebivolol for improving endothelial dysfunction, pulmonary vascular remodeling, and right heart function in pulmonary hypertension F Perros, B Ranchoux, M Izikki, S Bentebbal, C Happé, F Antigny, ... Journal of the American College of Cardiology 65 (7), 668-680, 2015 | 161 | 2015 |
| TGF-β and BMPR2 signaling in PAH: two black sheep in one family N Rol, KB Kurakula, C Happé, HJ Bogaard, MJ Goumans International journal of molecular sciences 19 (9), 2585, 2018 | 105 | 2018 |
| Delayed microvascular shear adaptation in pulmonary arterial hypertension. Role of platelet endothelial cell adhesion molecule-1 cleavage R Szulcek, CM Happe, N Rol, RD Fontijn, C Dickhoff, KJ Hartemink, ... American journal of respiratory and critical care medicine 193 (12), 1410-1420, 2016 | 104 | 2016 |
| Imatinib in patients with severe COVID-19: a randomised, double-blind, placebo-controlled, clinical trial J Aman, E Duijvelaar, L Botros, A Kianzad, JR Schippers, PJ Smeele, ... The Lancet Respiratory Medicine 9 (9), 957-968, 2021 | 102 | 2021 |
| Intravenous iron therapy in patients with idiopathic pulmonary arterial hypertension and iron deficiency G Ruiter, E Manders, CM Happé, I Schalij, H Groepenhoff, LS Howard, ... Pulmonary circulation 5 (3), 466-472, 2015 | 99 | 2015 |
| SuHx rat model: partly reversible pulmonary hypertension and progressive intima obstruction MA de Raaf, I Schalij, J Gomez-Arroyo, N Rol, C Happé, FS de Man, ... European Respiratory Journal 44 (1), 160-168, 2014 | 98 | 2014 |
| p38 MAPK inhibition improves heart function in pressure-loaded right ventricular hypertrophy B Kojonazarov, T Novoyatleva, M Boehm, C Happe, Z Sibinska, X Tian, ... American journal of respiratory cell and molecular biology 57 (5), 603-614, 2017 | 90 | 2017 |
| Bone morphogenetic protein receptor type 2 mutation in pulmonary arterial hypertension: a view on the right ventricle CE van der Bruggen, CM Happé, P Dorfmüller, P Trip, OA Spruijt, N Rol, ... Circulation 133 (18), 1747-1760, 2016 | 88 | 2016 |
| Nintedanib improves cardiac fibrosis but leaves pulmonary vascular remodelling unaltered in experimental pulmonary hypertension N Rol, MA de Raaf, XQ Sun, VP Kuiper, D da Silva Gonçalves Bos, ... Cardiovascular research 115 (2), 432-439, 2019 | 40 | 2019 |
| Renal denervation reduces pulmonary vascular remodeling and right ventricular diastolic stiffness in experimental pulmonary hypertension D da Silva Gonçalves Bos, C Happé, I Schalij, W Pijacka, JFR Paton, ... Basic to Translational Science 2 (1), 22-35, 2017 | 39 | 2017 |
| The BMP receptor 2 in pulmonary arterial hypertension: when and where the animal model matches the patient C Happé, K Kurakula, XQ Sun, D da Silva Goncalves Bos, N Rol, ... Cells 9 (6), 1422, 2020 | 35 | 2020 |
| Histone deacetylase inhibition with trichostatin A does not reverse severe angioproliferative pulmonary hypertension in rats (2013 Grover Conference series) MAD Raaf, AA Hussaini, JG Gomez-Arroyo, D Kraskaukas, D Farkas, ... Pulmonary Circulation 4 (2), 1-7, 2014 | 34 | 2014 |
| Prevention of progression of pulmonary hypertension by the Nur77 agonist 6-mercaptopurine: role of BMP signalling K Kurakula, XQ Sun, C Happé, DSG Bos, R Szulcek, I Schalij, ... European Respiratory Journal 54 (3), 2019 | 29 | 2019 |
| Pneumonectomy combined with SU5416 induces severe pulmonary hypertension in rats CM Happé, MA De Raaf, N Rol, I Schalij, A Vonk-Noordegraaf, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 310 …, 2016 | 29 | 2016 |
| Left ventricular outflow tract gradient is associated with reduced capillary density in hypertrophic cardiomyopathy irrespective of genotype A Güçlü, C Happé, S Eren, IH Korkmaz, HWM Niessen, P Klein, ... European journal of clinical investigation 45 (12), 1252-1259, 2015 | 22 | 2015 |
| Altered TGFβ/SMAD signaling in human and rat models of pulmonary hypertension: an old target needs attention TJ Sanada, XQ Sun, C Happé, C Guignabert, L Tu, I Schalij, HJ Bogaard, ... Cells 10 (1), 84, 2021 | 20 | 2021 |
| Levosimendan prevents and reverts right ventricular failure in experimental pulmonary arterial hypertension MS Hansen, A Andersen, S Holmboe, JG Schultz, S Ringgaard, ... Journal of Cardiovascular Pharmacology 70 (4), 232-238, 2017 | 15 | 2017 |
| Reconciling paradigms of abnormal pulmonary blood flow and quasi-malignant cellular alterations in pulmonary arterial hypertension CM Happe, R Szulcek, NF Voelkel, HJ Bogaard Vascular Pharmacology 83, 17-25, 2016 | 9 | 2016 |
| Vascular remodelling in the pulmonary circulation after major lung resection N Rol, C Happé, JAM Beliën, FS de Man, N Westerhof, ... European Respiratory Journal 50 (2), 2017 | 8 | 2017 |
