Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer YS Ju, LB Alexandrov, M Gerstung, I Martincorena, S Nik-Zainal, ... elife 3, e02935, 2014 | 397 | 2014 |
Myelodysplastic syndromes are propagated by rare and distinct human cancer stem cells in vivo PS Woll, U Kjällquist, O Chowdhury, H Doolittle, DC Wedge, S Thongjuea, ... Cancer cell 25 (6), 794-808, 2014 | 357 | 2014 |
Dynamic changes in histone acetylation regulate origins of DNA replication A Unnikrishnan, PR Gafken, T Tsukiyama Nature structural & molecular biology 17 (4), 430-437, 2010 | 233 | 2010 |
Genome-wide analysis of transcriptional regulators in human HSPCs reveals a densely interconnected network of coding and noncoding genes D Beck, JAI Thoms, D Perera, J Schütte, A Unnikrishnan, K Knezevic, ... Blood, The Journal of the American Society of Hematology 122 (14), e12-e22, 2013 | 156 | 2013 |
Integrative genomics identifies the molecular basis of resistance to azacitidine therapy in myelodysplastic syndromes A Unnikrishnan, E Papaemmanuil, D Beck, NP Deshpande, A Verma, ... Cell reports 20 (3), 572-585, 2017 | 118 | 2017 |
The RNA Atlas expands the catalog of human non-coding RNAs L Lorenzi, HS Chiu, F Avila Cobos, S Gross, PJ Volders, R Cannoodt, ... Nature biotechnology 39 (11), 1453-1465, 2021 | 103* | 2021 |
Functional mutations form at CTCF-cohesin binding sites in melanoma due to uneven nucleotide excision repair across the motif RC Poulos, JAI Thoms, YF Guan, A Unnikrishnan, JE Pimanda, ... Cell reports 17 (11), 2865-2872, 2016 | 80 | 2016 |
Human endogenous retroviruses form a reservoir of T cell targets in hematological cancers SK Saini, AD Ørskov, AM Bjerregaard, A Unnikrishnan, ... Nature communications 11 (1), 5660, 2020 | 64 | 2020 |
PDGF-AB and 5-Azacytidine induce conversion of somatic cells into tissue-regenerative multipotent stem cells V Chandrakanthan, A Yeola, JC Kwan, RA Oliver, Q Qiao, YC Kang, ... Proceedings of the National Academy of Sciences 113 (16), E2306-E2315, 2016 | 59 | 2016 |
Srsf2 P95H initiates myeloid bias and myelodysplastic/myeloproliferative syndrome from hemopoietic stem cells MF Smeets, SY Tan, JJ Xu, G Anande, A Unnikrishnan, AM Chalk, ... Blood, The Journal of the American Society of Hematology 132 (6), 608-621, 2018 | 50 | 2018 |
RNA splicing alterations induce a cellular stress response associated with poor prognosis in acute myeloid leukemia G Anande, NP Deshpande, S Mareschal, AMN Batcha, HR Hampton, ... Clinical Cancer Research 26 (14), 3597-3607, 2020 | 34 | 2020 |
Demethylation and up-regulation of an oncogene after hypomethylating therapy YC Liu, J Kwon, E Fabiani, Z Xiao, YV Liu, MY Follo, J Liu, H Huang, ... New England Journal of Medicine 386 (21), 1998-2010, 2022 | 28* | 2022 |
AZA-MS: a novel multiparameter mass spectrometry method to determine the intracellular dynamics of azacitidine therapy in vivo A Unnikrishnan, ANQ Vo, R Pickford, MJ Raftery, AC Nunez, A Verma, ... Leukemia 32 (4), 900-910, 2018 | 28 | 2018 |
Overexpression of ERG in cord blood progenitors promotes expansion and recapitulates molecular signatures of high ERG leukemias ML Tursky, D Beck, JAI Thoms, Y Huang, A Kumari, A Unnikrishnan, ... Leukemia 29 (4), 819-827, 2015 | 28 | 2015 |
Anticancer therapeutic effect of cerium-based nanoparticles: Known and unknown molecular mechanisms MJN Amaldoss, R Mehmood, JL Yang, P Koshy, N Kumar, ... Biomaterials Science 10 (14), 3671-3694, 2022 | 26 | 2022 |
HMGA2 promotes long-term engraftment and myeloerythroid differentiation of human hematopoietic stem and progenitor cells P Kumar, D Beck, R Galeev, JAI Thoms, MS Talkhoncheh, I de Jong, ... Blood Advances 3 (4), 681-691, 2019 | 24 | 2019 |
Inorganic nanoparticle-based advanced cancer therapies: Promising combination strategies MJN Amaldoss, JL Yang, P Koshy, A Unnikrishnan, CC Sorrell Drug Discovery Today 27 (12), 103386, 2022 | 23 | 2022 |
Constitutive CHK1 expression drives a pSTAT3–CIP2A circuit that promotes glioblastoma cell survival and growth A Khanna, JAI Thoms, BW Stringer, SA Chung, KS Ensbey, TR Jue, ... Molecular Cancer Research 18 (5), 709-722, 2020 | 23 | 2020 |
A quantitative proteomics approach identifies ETV6 and IKZF1 as new regulators of an ERG-driven transcriptional network A Unnikrishnan, YF Guan, Y Huang, D Beck, JAI Thoms, S Peirs, ... Nucleic acids research 44 (22), 10644-10661, 2016 | 20 | 2016 |
An Efficient Purification System for Native Minichromosome from Saccharomyces cerevisiae. A Unnikrishnan, B Akiyoshi, S Biggins, T Tsukiyama Methods in molecular biology (Clifton, NJ) 833, 115, 2012 | 19 | 2012 |