Translation of the Alzheimer amyloid precursor protein mRNA is up-regulated by interleukin-1 through 5′-untranslated region sequences JT Rogers, LM Leiter, J McPhee, CM Cahill, SS Zhan, H Potter, ... Journal of Biological Chemistry 274 (10), 6421-6431, 1999 | 399 | 1999 |
The Arctic Alzheimer mutation facilitates early intraneuronal Aβ aggregation and senile plaque formation in transgenic mice A Lord, H Kalimo, C Eckman, XQ Zhang, L Lannfelt, LNG Nilsson Neurobiology of aging 27 (1), 67-77, 2006 | 302 | 2006 |
Sensitive ELISA detection of amyloid‐β protofibrils in biological samples H Englund, D Sehlin, AS Johansson, LNG Nilsson, P Gellerfors, S Paulie, ... Journal of neurochemistry 103 (1), 334-345, 2007 | 269 | 2007 |
Glial activation and inflammation along the Alzheimer’s disease continuum K Nordengen, BE Kirsebom, K Henjum, P Selnes, B Gísladóttir, ... Journal of neuroinflammation 16, 1-13, 2019 | 220 | 2019 |
Imaging distinct conformational states of amyloid-β fibrils in Alzheimer’s disease using novel luminescent probes KPR Nilsson, A Åslund, I Berg, S Nyström, P Konradsson, A Herland, ... ACS chemical biology 2 (8), 553-560, 2007 | 217 | 2007 |
Loss of astrocyte polarization in the tg-ArcSwe mouse model of Alzheimer's disease J Yang, LK Lunde, P Nuntagij, T Oguchi, L Camassa, LNG Nilsson, ... Journal of Alzheimer's Disease 27 (4), 711-722, 2011 | 208 | 2011 |
α-1-Antichymotrypsin promotes β-sheet amyloid plaque deposition in a transgenic mouse model of Alzheimer's disease LNG Nilsson, KR Bales, G DiCarlo, MN Gordon, D Morgan, SM Paul, ... Journal of Neuroscience 21 (5), 1444-1451, 2001 | 179 | 2001 |
Animal models of amyloid‐β‐related pathologies in Alzheimer’s disease O Philipson, A Lord, A Gumucio, P O’Callaghan, L Lannfelt, LNG Nilsson The FEBS journal 277 (6), 1389-1409, 2010 | 136 | 2010 |
Cerebrospinal fluid soluble TREM2 in aging and Alzheimer’s disease K Henjum, IS Almdahl, V Årskog, L Minthon, O Hansson, T Fladby, ... Alzheimer's research & therapy 8, 1-11, 2016 | 135 | 2016 |
An amyloid-β protofibril-selective antibody prevents amyloid formation in a mouse model of Alzheimer's disease A Lord, A Gumucio, H Englund, D Sehlin, VS Sundquist, L Söderberg, ... Neurobiology of disease 36 (3), 425-434, 2009 | 132 | 2009 |
The inflammation-induced pathological chaperones ACT and apo-E are necessary catalysts of Alzheimer amyloid formation H Potter, IM Wefes, LNG Nilsson Neurobiology of aging 22 (6), 923-930, 2001 | 132 | 2001 |
A highly insoluble state of Aβ similar to that of Alzheimer's disease brain is found in Arctic APP transgenic mice O Philipson, P Hammarström, KPR Nilsson, E Portelius, T Olofsson, ... Neurobiology of aging 30 (9), 1393-1405, 2009 | 117 | 2009 |
Amyloid‐β protofibril levels correlate with spatial learning in Arctic Alzheimer’s disease transgenic mice A Lord, H Englund, L Söderberg, S Tucker, F Clausen, L Hillered, ... The FEBS journal 276 (4), 995-1006, 2009 | 112 | 2009 |
Amyloid‐β oligomers are inefficiently measured by enzyme‐linked immunosorbent assay C Stenh, H Englund, A Lord, AS Johansson, CG Almeida, P Gellerfors, ... Annals of neurology 58 (1), 147-150, 2005 | 112 | 2005 |
Cognitive impairment in PDAPP mice depends on ApoE and ACT-catalyzed amyloid formation LNG Nilsson, GW Arendash, RE Leighty, DA Costa, MA Low, MF Garcia, ... Neurobiology of aging 25 (9), 1153-1167, 2004 | 110 | 2004 |
Heparan sulfate accumulation with Aβ deposits in Alzheimer's disease and Tg2576 mice is contributed by glial cells P O'Callaghan, E Sandwall, JP Li, H Yu, R Ravid, ZZ Guan, ... Brain pathology 18 (4), 548-561, 2008 | 97 | 2008 |
Docosahexaenoic acid stimulates non‐amyloidogenic APP processing resulting in reduced Aβ levels in cellular models of Alzheimer's disease C Sahlin, FE Pettersson, LNG Nilsson, L Lannfelt, AS Johansson European Journal of Neuroscience 26 (4), 882-889, 2007 | 88 | 2007 |
The Arctic Alzheimer mutation favors intracellular amyloid‐β production by making amyloid precursor protein less available to α‐secretase C Sahlin, A Lord, K Magnusson, H Englund, CG Almeida, P Greengard, ... Journal of neurochemistry 101 (3), 854-862, 2007 | 84 | 2007 |
Specific uptake of an amyloid-β protofibril-binding antibody-tracer in AβPP transgenic mouse brain K Magnusson, D Sehlin, S Syvänen, MM Svedberg, O Philipson, ... Journal of Alzheimer's Disease 37 (1), 29-40, 2013 | 82 | 2013 |
The Alzheimer’s disease risk factors apolipoprotein E and TREM2 are linked in a receptor signaling pathway C Jendresen, V Årskog, MR Daws, LNG Nilsson Journal of neuroinflammation 14, 1-13, 2017 | 79 | 2017 |