IGF-binding proteins–the pieces are falling into place LA Bach, SJ Headey, RS Norton Trends in Endocrinology & Metabolism 16 (5), 228-234, 2005 | 211 | 2005 |
Small heat-shock proteins interact with a flanking domain to suppress polyglutamine aggregation AL Robertson, SJ Headey, HM Saunders, H Ecroyd, MJ Scanlon, ... Proceedings of the National Academy of Sciences 107 (23), 10424-10429, 2010 | 94 | 2010 |
Parallel screening of low molecular weight fragment libraries: do differences in methodology affect hit identification? J Wielens, SJ Headey, DI Rhodes, RJ Mulder, O Dolezal, JJ Deadman, ... Journal of Biomolecular Screening 18 (2), 147-159, 2013 | 81 | 2013 |
Application of Fragment‐Based Screening to the Design of Inhibitors of Escherichia coli DsbA LA Adams, P Sharma, B Mohanty, OV Ilyichova, MD Mulcair, ML Williams, ... Angewandte Chemie 127 (7), 2207-2212, 2015 | 57 | 2015 |
C-terminal domain of insulin-like growth factor (IGF) binding protein-6: structure and interaction with IGF-II SJ Headey, DW Keizer, S Yao, G Brasier, P Kantharidis, LA Bach, ... Molecular Endocrinology 18 (11), 2740-2750, 2004 | 57 | 2004 |
Enhanced homology-directed repair for highly efficient gene editing in hematopoietic stem/progenitor cells SS De Ravin, J Brault, RJ Meis, S Liu, L Li, M Pavel-Dinu, CR Lazzarotto, ... Blood, The Journal of the American Society of Hematology 137 (19), 2598-2608, 2021 | 52 | 2021 |
Contributions of the N-and C-terminal domains of IGF binding protein-6 to IGF binding SJ Headey, KS Leeding, RS Norton, LA Bach Journal of molecular endocrinology 33 (2), 377-386, 2004 | 51 | 2004 |
Crystal structure of the HIV-1 integrase core domain in complex with sucrose reveals details of an allosteric inhibitory binding site J Wielens, SJ Headey, D Jeevarajah, DI Rhodes, J Deadman, ... FEBS letters 584 (8), 1455-1462, 2010 | 50 | 2010 |
Conserved features in TamA enable interaction with TamB to drive the activity of the translocation and assembly module J Selkrig, MJ Belousoff, SJ Headey, E Heinz, T Shiota, HH Shen, ... Scientific reports 5 (1), 12905, 2015 | 43 | 2015 |
Structural basis for the inhibition of poxvirus assembly by the antibiotic rifampicin D Garriga, S Headey, C Accurso, M Gunzburg, M Scanlon, F Coulibaly Proceedings of the National Academy of Sciences 115 (33), 8424-8429, 2018 | 42 | 2018 |
Computational models of the gastrointestinal environment. 1. The effect of digestion on the phase behavior of intestinal fluids WA Birru, DB Warren, SJ Headey, H Benameur, CJH Porter, CW Pouton, ... Molecular Pharmaceutics 14 (3), 566-579, 2017 | 36 | 2017 |
Binding site for the C-domain of insulin-like growth factor (IGF) binding protein-6 on IGF-II; implications for inhibition of IGF actions SJ Headey, DW Keizer, S Yao, JC Wallace, LA Bach, RS Norton FEBS letters 568 (1-3), 19-22, 2004 | 35 | 2004 |
Fragment‐Based Design of Ligands Targeting a Novel Site on the Integrase Enzyme of Human Immunodeficiency Virus 1 J Wielens, SJ Headey, JJ Deadman, DI Rhodes, MW Parker, ... ChemMedChem 6 (2), 258-261, 2011 | 34 | 2011 |
Distinct binding properties of TIAR RRMs and linker region HS Kim, SJ Headey, YMK Yoga, MJ Scanlon, M Gorospe, MCJ Wilce, ... RNA biology 10 (4), 579-589, 2013 | 33 | 2013 |
The structure of integrin α1I domain in complex with a collagen-mimetic peptide YKY Chin, SJ Headey, B Mohanty, R Patil, PA McEwan, JD Swarbrick, ... Journal of Biological Chemistry 288 (52), 36796-36809, 2013 | 32 | 2013 |
Evolutionary differences in the Vegf/Vegfr code reveal organotypic roles for the endothelial cell receptor Kdr in developmental lymphangiogenesis AJ Vogrin, NI Bower, MJ Gunzburg, S Roufail, KS Okuda, S Paterson, ... Cell Reports 28 (8), 2023-2036. e4, 2019 | 31 | 2019 |
Δ‐Myrtoxin‐Mp1a is a helical heterodimer from the venom of the jack jumper ant that has antimicrobial, membrane‐disrupting, and nociceptive activities Z Dekan, SJ Headey, M Scanlon, BA Baldo, TH Lee, MI Aguilar, JR Deuis, ... Angewandte Chemie International Edition 56 (29), 8495-8499, 2017 | 31 | 2017 |
Characterization of two distinct modes of drug binding to human intestinal fatty acid binding protein R Patil, A Laguerre, J Wielens, SJ Headey, ML Williams, MLR Hughes, ... ACS chemical biology 9 (11), 2526-2534, 2014 | 30 | 2014 |
A picornaviral loop-to-loop replication complex JK Claridge, SJ Headey, JYH Chow, M Schwalbe, PJ Edwards, ... Journal of structural biology 166 (3), 251-262, 2009 | 26 | 2009 |
Identification of mechanistically distinct inhibitors of HIV-1 reverse transcriptase through fragment screening J La, CF Latham, RN Tinetti, A Johnson, D Tyssen, KD Huber, ... Proceedings of the National Academy of Sciences 112 (22), 6979-6984, 2015 | 25 | 2015 |