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Cagla Sahin
Cagla Sahin
Postdoc, Karolinska Institutet and University of Copenhagen
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Potent α-synuclein aggregation inhibitors, identified by high-throughput screening, mainly target the monomeric state
M Kurnik, C Sahin, CB Andersen, N Lorenzen, L Giehm, ...
Cell chemical biology 25 (11), 1389-1402. e9, 2018
772018
Oleuropein derivatives from olive fruit extracts reduce α-synuclein fibrillation and oligomer toxicity
H Mohammad-Beigi, F Aliakbari, C Sahin, C Lomax, A Tawfike, ...
Journal of Biological Chemistry 294 (11), 4215-4232, 2019
662019
Mechanistic understanding of the interactions between nano-objects with different surface properties and α-synuclein
H Mohammad-Beigi, A Hosseini, M Adeli, MR Ejtehadi, G Christiansen, ...
ACS nano 13 (3), 3243-3256, 2019
522019
A mass‐spectrometry‐based approach to distinguish annular and specific lipid binding to membrane proteins
JR Bolla, RA Corey, C Sahin, J Gault, A Hummer, JTS Hopper, DP Lane, ...
Angewandte Chemie 132 (9), 3551-3556, 2020
372020
Antibodies against the C-terminus of α-synuclein modulate its fibrillation
C Sahin, N Lorenzen, L Lemminger, G Christiansen, IM Møller, ...
Biophysical chemistry 220, 34-41, 2017
332017
Scratching the surface: native mass spectrometry of peripheral membrane protein complexes
C Sahin, DJ Reid, MT Marty, M Landreh
Biochemical Society Transactions 48 (2), 547-558, 2020
272020
Predicting the shapes of protein complexes through collision cross section measurements and database searches
M Landreh, C Sahin, J Gault, S Sadeghi, CL Drum, P Uzdavinys, D Drew, ...
Analytical Chemistry 92 (18), 12297-12303, 2020
242020
Early events in copper-ion catalyzed oxidation of α-synuclein
MK Tiwari, F Leinisch, C Sahin, IM Møller, DE Otzen, MJ Davies, ...
Free Radical Biology and Medicine 121, 38-50, 2018
242018
Order and disorder—An integrative structure of the full-length human growth hormone receptor
N Kassem, R Araya-Secchi, K Bugge, A Barclay, H Steinocher, ...
Science Advances 7 (27), eabh3805, 2021
232021
High intracellular stability of the spidroin N‐terminal domain in spite of abundant amyloidogenic segments revealed by in‐cell hydrogen/deuterium exchange mass spectrometry
M Kaldmäe, A Leppert, G Chen, M Sarr, C Sahin, K Nordling, N Kronqvist, ...
The FEBS Journal 287 (13), 2823-2833, 2020
192020
Gas-Phase Collisions with Trimethylamine-N-Oxide Enable Activation-Controlled Protein Ion Charge Reduction
M Kaldmäe, N Österlund, D Lianoudaki, C Sahin, P Bergman, T Nyman, ...
Journal of The American Society for Mass Spectrometry 30 (8), 1385-1388, 2019
192019
α-Synucleins from animal species show low fibrillation propensities and weak oligomer membrane disruption
C Sahin, L Kjær, MS Christensen, J N. Pedersen, G Christiansen, ...
Biochemistry 57 (34), 5145-5158, 2018
192018
A strategy for the identification of protein architectures directly from ion mobility mass spectrometry data reveals stabilizing subunit interactions in light harvesting complexes
M Kaldmäe, C Sahin, M Saluri, EG Marklund, M Landreh
Protein Science 28 (6), 1024-1030, 2019
172019
Charge engineering reveals the roles of ionizable side chains in electrospray ionization mass spectrometry
ML Abramsson, C Sahin, JTS Hopper, RMM Branca, J Danielsson, M Xu, ...
JACS Au 1 (12), 2385-2393, 2021
162021
Spidroin N-terminal domain forms amyloid-like fibril based hydrogels and provides a protein immobilization platform
T Arndt, K Jaudzems, O Shilkova, J Francis, M Johansson, PR Laity, ...
Nature Communications 13 (1), 4695, 2022
112022
Liquid–liquid phase separation primes spider silk proteins for fiber formation via a conditional sticker domain
A Leppert, G Chen, D Lama, C Sahin, V Railaite, O Shilkova, T Arndt, ...
Nano Letters 23 (12), 5836-5841, 2023
102023
The changing face of aging: highly sulfated glycosaminoglycans induce amyloid formation in a lattice corneal dystrophy model protein
KG Malmos, M Stenvang, C Sahin, G Christiansen, DE Otzen
Journal of Molecular Biology 429 (18), 2755-2764, 2017
102017
Mass spectrometry of RNA-binding proteins during liquid–liquid phase separation reveals distinct assembly mechanisms and droplet architectures
C Sahin, A Motso, X Gu, H Feyrer, D Lama, T Arndt, A Rising, GV Gese, ...
Journal of the American Chemical Society 145 (19), 10659-10668, 2023
92023
Mass spectrometry and machine learning reveal determinants of client recognition by antiamyloid chaperones
N Österlund, T Vosselman, A Leppert, A Gräslund, H Jörnvall, LL Ilag, ...
Molecular & Cellular Proteomics 21 (10), 2022
92022
Structural basis for dityrosine-mediated inhibition of α-synuclein fibrillization
C Sahin, EC Østerlund, N Österlund, J Costeira-Paulo, JN Pedersen, ...
Journal of the American Chemical Society 144 (27), 11949-11954, 2022
92022
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