Integrated Multi-Omics Analyses in Oncology: A Review of Machine Learning Methods and Tools G Nicora, F Vitali, A Dagliati, N Geifman, R Bellazzi Frontiers in Oncology 10 (1030), 2020 | 202 | 2020 |
MTGO: PPI network analysis via topological and functional module identification D Vella, S Marini, F Vitali, D Di Silvestre, G Mauri, R Bellazzi Scientific reports 8 (1), 5499, 2018 | 134 | 2018 |
A network-based data integration approach to support drug repurposing and multi-target therapies in triple negative breast cancer F Vitali, LD Cohen, A Demartini, A Amato, V Eterno, A Zambelli, R Bellazzi PloS one 11 (9), e0162407, 2016 | 75 | 2016 |
Loss of fatty acid degradation by astrocytic mitochondria triggers neuroinflammation and neurodegeneration Y Mi, G Qi, F Vitali, Y Shang, AC Raikes, T Wang, Y Jin, RD Brinton, H Gu, ... Nature metabolism 5 (3), 445-465, 2023 | 72 | 2023 |
Statin therapy and risk of Alzheimer's and age‐related neurodegenerative diseases G Torrandell‐Haro, GL Branigan, F Vitali, N Geifman, JM Zissimopoulos, ... Alzheimer's & Dementia: Translational Research & Clinical Interventions 6 (1 …, 2020 | 64 | 2020 |
Network-based target ranking for polypharmacological therapies F Vitali, F Mulas, P Marini, R Bellazzi Journal of Biomedical Informatics 46 (5), 876-881, 2013 | 48 | 2013 |
Autologous micrograft accelerates endogenous wound healing response through ERK-induced cell migration M Balli, F Vitali, A Janiszewski, E Caluwé, A Cortés-Calabuig, ... Cell Death & Differentiation 27 (5), 1520-1538, 2020 | 42 | 2020 |
A variant within the FTO confers susceptibility to diabetic nephropathy in Japanese patients with type 2 diabetes M Taira, M Imamura, A Takahashi, Y Kamatani, T Yamauchi, S Araki, ... PlosOne 13 (12), 2018 | 37 | 2018 |
Developing a ‘personalome’for precision medicine: emerging methods that compute interpretable effect sizes from single-subject transcriptomes F Vitali, Q Li, AG Schissler, J Berghout, C Kenost, YA Lussier Briefings in bioinformatics 20 (3), 789-805, 2019 | 32 | 2019 |
A tale of two systems: Lessons learned from female mid-life aging with implications for Alzheimer’s prevention & treatment A Mishra, Y Wang, F Yin, F Vitali, KE Rodgers, M Soto, L Mosconi, T Wang, ... Ageing research reviews 74, 101542, 2022 | 22 | 2022 |
Patient similarity by joint matrix trifactorization to identify subgroups in acute myeloid leukemia F Vitali, S Marini, D Pala, A Demartini, S Montoli, A Zambelli, R Bellazzi JAMIA open 1 (1), 75-86, 2018 | 22 | 2018 |
Evaluating single-subject study methods for personal transcriptomic interpretations to advance precision medicine S Rachid Zaim, C Kenost, J Berghout, F Vitali, HH Zhang, YA Lussier BMC medical genomics 12, 1-15, 2019 | 13 | 2019 |
Protease target prediction via matrix factorization S Marini*, F Vitali*, *(first co-author), S Rampazzi, A Demartini, T Akutsu Bioinformatics, 2018 | 11 | 2018 |
Novel disease syndromes unveiled by integrative multiscale network analysis of diseases sharing molecular effectors and comorbidities H Li, J Fan, F Vitali, J Berghout, D Aberasturi, J Li, L Wilson, W Chiu, ... BMC medical genomics 11, 1-15, 2018 | 10 | 2018 |
Interpretation of ‘Omics dynamics in a single subject using local estimates of dispersion between two transcriptomes Q Li, SR Zaim, D Aberasturi, J Berghout, H Li, F Vitali, C Kenost, ... AMIA Annual Symposium Proceedings 2019, 582, 2019 | 9 | 2019 |
Contributions of sex and genotype to exploratory behavior differences in an aged humanized APOE mouse model of late-onset Alzheimer's disease JW McLean, A Bhattrai, F Vitali, AC Raikes, JPL Wiegand, RD Brinton Learning & Memory 29 (9), 321-331, 2022 | 8 | 2022 |
Precision drug repurposing via convergent eQTL-based molecules and pathway targeting independent disease-associated polymorphisms F Vitali, J Berghout, J Fan, J Li, Q Li, H Li, YA Lussier Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing 24, 308, 2019 | 8 | 2019 |
Exploring wound-healing genomic machinery with a network-based approach F Vitali, S Marini, M Balli, H Grosemans, M Sampaolesi, YA Lussier, ... Pharmaceuticals 10 (2), 55, 2017 | 8 | 2017 |
Preventing Alzheimer's disease within reach by 2025: Targeted‐risk‐AD‐prevention (TRAP) strategy F Vitali, GL Branigan, RD Brinton Alzheimer's & Dementia: Translational Research & Clinical Interventions 7 (1 …, 2021 | 7 | 2021 |
A Bayesian data fusion based approach for learning genome-wide transcriptional regulatory networks E Sauta, A Demartini, F Vitali, A Riva, R Bellazzi BMC Bioinformatics 21 (219), 2020 | 6 | 2020 |