| Illuminating G-protein-coupling selectivity of GPCRs A Inoue, F Raimondi, FMN Kadji, G Singh, T Kishi, A Uwamizu, Y Ono, ... Cell 177 (7), 1933-1947. e25, 2019 | 417 | 2019 |
| A platform of synthetic lethal gene interaction networks reveals that the GNAQ uveal melanoma oncogene controls the Hippo pathway through FAK X Feng*, N Arang*, DC Rigiracciolo, JS Lee, H Yeerna, Z Wang, ... Cancer cell 35 (3), 457-472. e5, 2019 | 211 | 2019 |
| Malaria parasites target the hepatocyte receptor EphA2 for successful host infection A Kaushansky, AN Douglass, N Arang, V Vigdorovich, N Dambrauskas, ... Science 350 (6264), 1089-1092, 2015 | 135 | 2015 |
| G Protein‐Coupled receptors and heterotrimeric G proteins as cancer drivers N Arang, JS Gutkind FEBS letters 594 (24), 4201-4232, 2020 | 94 | 2020 |
| Liver stage malaria infection is controlled by host regulators of lipid peroxidation HS Kain, EKK Glennon, K Vijayan, N Arang, AN Douglass, CL Fortin, ... Cell Death & Differentiation 27 (1), 44-54, 2020 | 69 | 2020 |
| Synthetic Lethal Screens Reveal Cotargeting FAK and MEK as a Multimodal Precision Therapy for GNAQ-Driven Uveal Melanoma JS Paradis, M Acosta, R Saddawi-Konefka, A Kishore, S Lubrano, ... Clinical Cancer Research 27 (11), 3190-3200, 2021 | 47 | 2021 |
| SSP3 is a novel Plasmodium yoelii sporozoite surface protein with a role in gliding motility A Harupa, BK Sack, V Lakshmanan, N Arang, AN Douglass, BG Oliver, ... Infection and immunity 82 (11), 4643-4653, 2014 | 36 | 2014 |
| Host-based prophylaxis successfully targets liver stage malaria parasites AN Douglass, HS Kain, M Abdullahi, N Arang, LS Austin, SA Mikolajczak, ... Molecular Therapy 23 (5), 857-865, 2015 | 35 | 2015 |
| Identifying host regulators and inhibitors of liver stage malaria infection using kinase activity profiles N Arang, HS Kain, EK Glennon, T Bello, DR Dudgeon, ENF Walter, ... Nature communications 8 (1), 1232, 2017 | 34 | 2017 |
| Gαs–Protein Kinase A (PKA) Pathway Signalopathies: The Emerging Genetic Landscape and Therapeutic Potential of Human Diseases Driven by Aberrant Gαs-PKA Signaling DJ Ramms, F Raimondi, N Arang, FW Herberg, SS Taylor, JS Gutkind Pharmacological Reviews 73 (4), 155-197, 2021 | 33 | 2021 |
| Muscarinic receptors promote castration-resistant growth of prostate cancer through a FAK–YAP signaling axis Y Goto, T Ando, H Izumi, X Feng, N Arang, M Gilardi, Z Wang, K Ando, ... Oncogene 39 (20), 4014-4027, 2020 | 29 | 2020 |
| Susceptibility to Plasmodium yoelii preerythrocytic infection in BALB/c substrains is determined at the point of hepatocyte invasion A Kaushansky, LS Austin, SA Mikolajczak, FY Lo, JL Miller, AN Douglass, ... Infection and immunity 83 (1), 39-47, 2015 | 27 | 2015 |
| EGFR Regulates the Hippo pathway by promoting the tyrosine phosphorylation of MOB1 T Ando, N Arang, Z Wang, DE Costea, X Feng, Y Goto, H Izumi, M Gilardi, ... Communications Biology 4 (1), 1237, 2021 | 24 | 2021 |
| Focal Adhesion Kinase (FAK)-Hippo/YAP transduction signaling mediates the stimulatory effects exerted by S100A8/A9-RAGE system in triple-negative breast cancer (TNBC) DC Rigiracciolo, N Nohata, R Lappano, F Cirillo, M Talia, ... Journal of Experimental & Clinical Cancer Research 41 (1), 193, 2022 | 23 | 2022 |
| Structure of the C-terminal guanine nucleotide exchange factor module of Trio in an autoinhibited conformation reveals its oncogenic potential SJ Bandekar, N Arang, ES Tully, BA Tang, BL Barton, S Li, JS Gutkind, ... Science signaling 12 (569), eaav2449, 2019 | 23 | 2019 |
| A genome-wide CRISPR-Cas9 screen identifies CENPJ as a host regulator of altered microtubule organization during Plasmodium liver infection K Vijayan, N Arang, L Wei, R Morrison, R Geiger, KR Parks, AJ Lewis, ... Cell chemical biology 29 (9), 1419-1433. e5, 2022 | 14 | 2022 |
| Alterations in phosphorylation of hepatocyte ribosomal protein S6 control plasmodium liver stage infection EKK Glennon, LS Austin, N Arang, HS Kain, FD Mast, K Vijayan, ... Cell reports 26 (12), 3391-3399. e4, 2019 | 13 | 2019 |
| Whole-genome CRISPR screening identifies PI3K/AKT as a downstream component of the oncogenic GNAQ–focal adhesion kinase signaling circuitry N Arang, S Lubrano, DC Rigiracciolo, D Nachmanson, SM Lippman, ... Journal of Biological Chemistry 299 (2), 2022 | 6 | 2022 |
| Cyclosporine Induces Fenestra-Associated Injury in Human Renal Microvessels In Vitro RJ Nagao, R Marcu, YJ Shin, D Lih, J Xue, N Arang, L Wei, S Akilesh, ... ACS Biomaterials Science & Engineering 8 (1), 196-207, 2021 | 5 | 2021 |
| A genome-wide CRISPR-Cas9 screen identifies host factors essential for optimal Plasmodium liver stage development K Vijayan, N Arang, L Wei, R Morrison, R Geiger, KR Parks, AJ Lewis, ... bioRxiv 10 (2020.08), 31.275867, 2020 | 5 | 2020 |
J. Silvio Gutkind, Ph.D.UCSD, Distinguished Professor and Chair, Dept. Pharmacology, AD Basic Science Moores Cancer CenterDirección de correo verificada de ucsd.edu
