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Shin-Ichiro Miyashita
Shin-Ichiro Miyashita
Assistant professor, Tokyo University of Agriculture
Verified email at nodai.ac.jp
Title
Cited by
Cited by
Year
Massively parallel de novo protein design for targeted therapeutics
A Chevalier, DA Silva, GJ Rocklin, DR Hicks, R Vergara, P Murapa, ...
Nature 550 (7674), 74-79, 2017
4672017
Identification and characterization of a novel botulinum neurotoxin
S Zhang, G Masuyer, J Zhang, Y Shen, D Lundin, L Henriksson, ...
Nature communications 8 (1), 14130, 2017
2702017
Identification of a botulinum neurotoxin-like toxin in a commensal strain of Enterococcus faecium
S Zhang, F Lebreton, MJ Mansfield, SI Miyashita, J Zhang, ...
Cell host & microbe 23 (2), 169-176. e6, 2018
1572018
Genetically encoded fluorescent indicators for imaging intracellular potassium ion concentration
Y Shen, SY Wu, V Rancic, A Aggarwal, Y Qian, SI Miyashita, K Ballanyi, ...
Communications biology 2 (1), 18, 2019
1252019
Sulfated glycosaminoglycans and low-density lipoprotein receptor contribute to Clostridium difficile toxin A entry into cells
L Tao, S Tian, J Zhang, Z Liu, L Robinson-McCarthy, SI Miyashita, ...
Nature microbiology 4 (10), 1760-1769, 2019
972019
Delivery of single-domain antibodies into neurons using a chimeric toxin–based platform is therapeutic in mouse models of botulism
SI Miyashita, J Zhang, S Zhang, CB Shoemaker, M Dong
Science Translational Medicine 13 (575), eaaz4197, 2021
462021
Characterization of a membrane binding loop leads to engineering botulinum neurotoxin B with improved therapeutic efficacy
L Yin, G Masuyer, S Zhang, J Zhang, SI Miyashita, D Burgin, L Lovelock, ...
PLoS biology 18 (3), e3000618, 2020
212020
Small-angle X-ray scattering reveals structural dynamics of the botulinum neurotoxin associating protein, nontoxic nonhemagglutinin
Y Sagane, SI Miyashita, K Miyata, T Matsumoto, K Inui, S Hayashi, ...
Biochemical and biophysical research communications 425 (2), 256-260, 2012
202012
“Non-Toxic” Proteins of the Botulinum Toxin Complex Exert In-vivo Toxicity
SI Miyashita, Y Sagane, T Suzuki, T Matsumoto, K Niwa, T Watanabe
Scientific reports 6 (1), 31043, 2016
192016
Toxic and nontoxic components of botulinum neurotoxin complex are evolved from a common ancestral zinc protein
K Inui, Y Sagane, K Miyata, SI Miyashita, T Suzuki, Y Shikamori, ...
Biochemical and biophysical research communications 419 (3), 500-504, 2012
192012
Covalent modifiers of Botulinum neurotoxin counteract toxin persistence
M Garland, BM Babin, SI Miyashita, S Loscher, Y Shen, M Dong, M Bogyo
ACS chemical biology 14 (1), 76-87, 2018
152018
Sugar-induced conformational change found in the HA-33/HA-17 trimer of the botulinum toxin complex
Y Sagane, S Hayashi, T Matsumoto, SI Miyashita, K Inui, K Miyata, ...
Biochemical and biophysical research communications 438 (3), 483-487, 2013
102013
Purification and characterization of nontoxic protein complex from serotype D 4947 botulinum toxin complex
K Miyata, Y Sagane, K Inui, SI Miyashita, T Suzuki, K Oguma, T Ohyama, ...
The Protein Journal 31, 387-392, 2012
82012
Genetically encoded ratiometric indicators for potassium ion
Y Shen, SY Wu, V Rancic, Y Qian, SI Miyashita, K Ballanyi, RE Campbell, ...
BioRxiv, 254383, 2018
72018
Hemagglutinin gene shuffling among Clostridium botulinum serotypes C and D yields distinct sugar recognition of the botulinum toxin complex
K Miyata, T Suzuki, S Hayashi, SI Miyashita, T Ohyama, K Niwa, ...
Pathogens and Disease 73 (7), ftv054, 2015
72015
Crystallization and preliminary X-ray analysis of a novel haemagglutinin component of the toxin complex of serotype C Clostridium botulinum
S Hayashi, T Akiyama, Y Sagane, SI Miyashita, T Watanabe, S Yajima, ...
Acta Crystallographica Section F: Structural Biology Communications 70 (3 …, 2014
62014
Botulinum toxin complex: a delivery vehicle of botulinum neurotoxin traveling digestive tract
Y Sagane, K Inui, SI Miyashita, K Miyata, K Niwa, T Watanabe, T Suzuki
Structure and Function of Food Engineering. InTech, Rijeka, 137-150, 2012
62012
Crystallization and preliminary X-ray analysis of the Clostridium botulinum type D nontoxic nonhaemagglutinin
K Miyata, K Inui, SI Miyashita, Y Sagane, K Hasegawa, T Matsumoto, ...
Acta Crystallographica Section F: Structural Biology and Crystallization …, 2012
62012
Transport of the botulinum neurotoxin–associating protein, nontoxic nonhemagglutinin, across the rat small intestinal epithelial cell monolayer
SI Miyashita, Y Sagane, K Niwa, T Watanabe
FEMS microbiology letters 346 (1), 73-80, 2013
52013
Random phage display-based screening of peptides that bind to botulinum neurotoxin binding protein, nontoxic nonhemagglutinin
Y Sagane, K Miyata, S Kurihara, T Yoneyama, K Inui, SI Miyashita, ...
Current microbiology 67, 188-192, 2013
42013
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